BBa_K1926003
1
BBa_K1926003
A cyclic promoter of CDK4 from human genome
2016-10-08T11:00:00Z
2016-10-19T01:16:14Z
The sequence was retrieved from Addgene. We got it from human genome through PCR using the following primers:
pCDK4-F: TGGTGGAGCGAAAAGGTGACAGCATC
pCDK4-R: GCGGAAACTGGGAGGGCGGGGCGAA
(Product: 457)
This part is a cyclic promoter named CDK4 from human genome. It can lead to transcription of the downstream DNA sequence in every G1 phase[4].
4. Guo, Z.Y., et al., The elements of human cyclin D1 promoter and regulation involved. Clin Epigenetics, 2011. 2(2): p. 63-76.
You may use this part to:
1) Express something in mammal cell lines particularly in G1 phases or once in every cell cycle by stable transfecting it into cell line;
2) Use it as a human promoter by transient transfecting it into cells.
false
false
_2393_
28998
28998
9
false
None
false
Xinyi Liu
annotation2491731
1
mutate C into A to remove Pst1
range2491731
1
284
284
annotation2491730
1
P CDK4
range2491730
1
65
522
BBa_K1926003_sequence
1
gcagtttggactagcattctaccgggtaggggaggcgcttttcccaaggcagtctggagcatgctggtggagcgaaaaggtgacagcatcacctctggtaccccaactcccaccccctccccaatgcagacaggctgaaagaccggtagtgagactggagttcagccttcagaccggtagtgagacaatccttcagccgggagttgggctctgggtggcctaggttgccatggcaccgcctcgggctccaccctctcttgtccccctcaccgctccccccctgaagcgggggttgtggcagccagtcacgtgcccgccgcgtagccacacctctgctcctcagagcaatgtcaagcggtcacgtgtgatagcaacagatcacgtggctgccatcgcccctccgcccccttacactcttcgccctcctcccagtcgaagcacctcctgtccgcccctcagcgcatgggtggcggtcacgtgcccagaacgtccggcgttcgccccgccctcccagtttccgcgctagctagctcgaggttatcaaacaagtttgtacaaaaaagctgaacgagaaacgtaaaatgatatt
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z