BBa_J23105
1
BBa_J23105
constitutive promoter family member
2006-08-13T11:00:00Z
2015-08-31T04:08:40Z
Isolated from library of promoters
Later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_K1933000
1
BclA-His
N-terminal domain of BclA protein fused to 6xHis tag
2016-10-09T11:00:00Z
2016-10-17T12:19:04Z
NCBI accession number CAD56880
NCBI accession number CAD56878
NCBI accession number CAD56869
NCBI accession number CAD56870
This part codes N-terminal domain of BclA protein which expressed on the cell surface connected by a 6??His tag to be easily identified by Western blotting.[1] Surface displayed passengers retain enzyme activity even when it is linked to BclA with 6?? His tag.
false
false
_2400_
23701
29998
9
false
optimized to expression in E. coli K-12 strain
false
Tomoki Uchino
annotation2490248
1
start codon
range2490248
1
1
3
annotation2490250
1
6xHis tag
range2490250
1
67
84
annotation2490249
1
BclA
range2490249
1
4
66
BBa_K1933003
1
BBa_K1933003
constitutive expression of CBDclos fused to BclA with 6xHis tag
2016-10-09T11:00:00Z
2016-10-10T08:34:03Z
The BclA surface expression component derives from Bacillus anthracis(34F2), it is a hair-like protein that covers B. anthracis??? spores. We used parts BBa_K1933000 from iGEMKyoto 2016 for construction. We outsourced chemical synthesis of this part for construction. CBDclos derives from Clostridium cellulovorans, and is part of a multi-unit cellulosomes. We used parts BBa_K1321341 from iGEM Imperial 2014 for construction.
CBDclos fused to BclA with 6xHis tag is one of a series of surface expressing fusion proteins that make up biodevice that aims to be therapeutic solution against norovirus infections. This protein in particular is a cellulose binding protein(CBD) fused to surface expression anchoring domain(BclA), connected by a 6xHis tag to be easily identified by Western blotting.
For more information, please visit our <a ref=http://2016.igem.org/Team:Kyoto> Wiki page</a>.
true
false
_2400_
29998
29998
9
false
BclA sequence was optimized to expression in E. coli K-12
false
Tomoki Uchino
component2490215
1
BBa_K1933000
component2490210
1
BBa_B0034
component2490216
1
BBa_K1321002
component2490208
1
BBa_J23105
annotation2490210
1
BBa_B0034
range2490210
1
36
47
annotation2490208
1
BBa_J23105
range2490208
1
1
35
annotation2490215
1
BBa_K1933000
range2490215
1
48
137
annotation2490216
1
BBa_K1321002
range2490216
1
138
437
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K1321002
1
BBa_K1321002
Re-entry of BBa_K863111, Cellulose Binding Domain CBDclos in rfc25
2014-10-09T11:00:00Z
2015-06-17T12:35:41Z
This is a direct copy of BBa_K863111 with slight modifications to the beginning and end of the sequence for the purposes of allowing composite parts to be added correctly using this part.
This part is a copy of BBa_K863111 (Cellulose binding domain of C. cellulovorans cellulose binding protein gene (Freiburg-Standard)) and was created only as a registry entry, removing the atg-NgoMIV parts at the front and the AgeI-taa basepairs from the sequence so that the registry does not flag it as rfc25 incompatible, and it enables us to enter fusion proteins with this part as automatic composite parts in the method as described by: http://2009.igem.org/Team:Freiburg_bioware/general.
false
false
_1696_
4206
20780
9
Not in stock
false
This is a direct copy of BBa_K863111 with slight modifications to the beginning and end of the sequence for the purposes of allowing composite parts to be added correctly using this part.
false
Xenia Spencer-Milnes
BBa_B0034_sequence
1
aaagaggagaaa
BBa_J23105_sequence
1
tttacggctagctcagtcctaggtactatgctagc
BBa_K1933000_sequence
1
atggcgttcgacccgaacctggttggtccgaccctgccgccgatcccgccgttcaccctgccgacccatcatcatcatcatcat
BBa_K1933003_sequence
1
tttacggctagctcagtcctaggtactatgctagcaaagaggagaaaatggcgttcgacccgaacctggttggtccgaccctgccgccgatcccgccgttcaccctgccgacccatcatcatcatcatcattaataatcatcaatgtcagttgaattttacaactctaacaaatcagcacaaacaaactcaattacaccaataatcaaaattactaacacgtctgacagtgatttaaatttaaatgacgtaaaagttagatattattacacaagtgatggtacacaaggacaaactttctggtgtgaccatgctggtgcattattaggaaatagctatgttgataacactagcaaagtgacagcaaacttcgttaaagaaacagcaagcccaacatcaacctatgatacatatgttgaatttggatttgcaggcagc
BBa_K1321002_sequence
1
tcatcaatgtcagttgaattttacaactctaacaaatcagcacaaacaaactcaattacaccaataatcaaaattactaacacgtctgacagtgatttaaatttaaatgacgtaaaagttagatattattacacaagtgatggtacacaaggacaaactttctggtgtgaccatgctggtgcattattaggaaatagctatgttgataacactagcaaagtgacagcaaacttcgttaaagaaacagcaagcccaacatcaacctatgatacatatgttgaatttggatttgcaggcagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z