BBa_K1933000
1
BclA-His
N-terminal domain of BclA protein fused to 6xHis tag
2016-10-09T11:00:00Z
2016-10-17T12:19:04Z
NCBI accession number CAD56880
NCBI accession number CAD56878
NCBI accession number CAD56869
NCBI accession number CAD56870
This part codes N-terminal domain of BclA protein which expressed on the cell surface connected by a 6??His tag to be easily identified by Western blotting.[1] Surface displayed passengers retain enzyme activity even when it is linked to BclA with 6?? His tag.
false
false
_2400_
23701
29998
9
false
optimized to expression in E. coli K-12 strain
false
Tomoki Uchino
annotation2490249
1
BclA
range2490249
1
4
66
annotation2490248
1
start codon
range2490248
1
1
3
annotation2490250
1
6xHis tag
range2490250
1
67
84
BBa_K1321002
1
BBa_K1321002
Re-entry of BBa_K863111, Cellulose Binding Domain CBDclos in rfc25
2014-10-09T11:00:00Z
2015-06-17T12:35:41Z
This is a direct copy of BBa_K863111 with slight modifications to the beginning and end of the sequence for the purposes of allowing composite parts to be added correctly using this part.
This part is a copy of BBa_K863111 (Cellulose binding domain of C. cellulovorans cellulose binding protein gene (Freiburg-Standard)) and was created only as a registry entry, removing the atg-NgoMIV parts at the front and the AgeI-taa basepairs from the sequence so that the registry does not flag it as rfc25 incompatible, and it enables us to enter fusion proteins with this part as automatic composite parts in the method as described by: http://2009.igem.org/Team:Freiburg_bioware/general.
false
false
_1696_
4206
20780
9
Not in stock
false
This is a direct copy of BBa_K863111 with slight modifications to the beginning and end of the sequence for the purposes of allowing composite parts to be added correctly using this part.
false
Xenia Spencer-Milnes
BBa_K1933004
1
BBa_K1933004
constitutive promoter and RBS
2016-10-09T11:00:00Z
2016-10-10T09:38:21Z
BBa_J23105 was designed by John Anderson and BBa_B0034 was designed by Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003. This sequence was chemically synthesized.
This part codes costitutive promoter(BBa_J23105) and RBS(BBa_B0034). Most parts were expressioned by this part in our project.
false
false
_2400_
29998
29998
9
false
7bp after promoter and 6bp after RBS
false
Tomoki Uchino
annotation2490322
1
nonsense sequence
range2490322
1
36
42
annotation2490408
1
constitutive promoter and RBS
range2490408
1
1
60
annotation2490404
1
Re-entry of BBa_B0034
range2490404
1
43
54
annotation2490323
1
Re-entry of BBa_J23105
range2490323
1
1
35
annotation2490405
1
scar
range2490405
1
55
60
BBa_K1933103
1
BBa_K1933103
constitutive expression of CBDclos fused to BclA with 6xHis tag
2016-10-09T11:00:00Z
2016-10-18T11:05:25Z
The BclA surface expression component derives from Bacillus anthracis(34F2), it is a hair-like protein that covers B. anthracis??? spores. We used parts BBa_K1933000 from iGEMKyoto 2016 for construction. We outsourced chemical synthesis of this part for construction. CBDclos derives from Clostridium cellulovorans, and is part of a multi-unit cellulosomes. We used parts BBa_K1321341 from iGEM Imperial 2014 for construction.
CBDclos fused to BclA with 6xHis tag is one of a series of surface expressing fusion proteins that make up biodevice that aims to be therapeutic solution against norovirus infections. This protein in particular is a cellulose binding protein(CBD) fused to surface expression anchoring domain(BclA), connected by a 6xHis tag to be easily identified by Western blotting.
For more information, please visit our <a ref=http://2016.igem.org/Team:Kyoto> Wiki page</a>.
false
false
_2400_
23701
29998
9
false
The stop codon for this part is not in the coding region, but in the suffix region.
false
Tomoki Uchino
component2490480
1
BBa_K1933000
component2490476
1
BBa_K1933004
component2490481
1
BBa_K1321002
annotation2490481
1
BBa_K1321002
range2490481
1
145
444
annotation2490480
1
BBa_K1933000
range2490480
1
61
144
annotation2490476
1
BBa_K1933004
range2490476
1
1
60
BBa_K1933103_sequence
1
tttacggctagctcagtcctaggtactatgctagcactagagaaagaggagaaatactagatggcgttcgacccgaacctggttggtccgaccctgccgccgatcccgccgttcaccctgccgacccatcatcatcatcatcattcatcaatgtcagttgaattttacaactctaacaaatcagcacaaacaaactcaattacaccaataatcaaaattactaacacgtctgacagtgatttaaatttaaatgacgtaaaagttagatattattacacaagtgatggtacacaaggacaaactttctggtgtgaccatgctggtgcattattaggaaatagctatgttgataacactagcaaagtgacagcaaacttcgttaaagaaacagcaagcccaacatcaacctatgatacatatgttgaatttggatttgcaggcagc
BBa_K1933000_sequence
1
atggcgttcgacccgaacctggttggtccgaccctgccgccgatcccgccgttcaccctgccgacccatcatcatcatcatcat
BBa_K1321002_sequence
1
tcatcaatgtcagttgaattttacaactctaacaaatcagcacaaacaaactcaattacaccaataatcaaaattactaacacgtctgacagtgatttaaatttaaatgacgtaaaagttagatattattacacaagtgatggtacacaaggacaaactttctggtgtgaccatgctggtgcattattaggaaatagctatgttgataacactagcaaagtgacagcaaacttcgttaaagaaacagcaagcccaacatcaacctatgatacatatgttgaatttggatttgcaggcagc
BBa_K1933004_sequence
1
tttacggctagctcagtcctaggtactatgctagcactagagaaagaggagaaatactag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z