BBa_K1940000
1
BBa_K1940000
anti-microRNA-34c
2016-10-10T11:00:00Z
2016-10-13T09:32:59Z
Homo sapiens (human),Chromosome 11, NC_000011.10 (111513439..111513515)
Anti- microRNA-34c can be used as a miR-34c detector. MiR-34c is significantly upregulated in Alzheimer's disease (AD) patients. Several researches have suggested that strategies to manipulate miR-34c could open a suitable novel virus-free therapeutic avenue to treat cognitive diseases. In this part, we designed 4 series antisense strand of miR-34c which are linked by 4 linkers. Anti- microRNA-34c is sensitive to the expression levels of miR-34c. And combined with a reporter, we can diagnose AD accurately and rapidly.
false
false
_2407_
30070
30070
9
true
4 copies of anti-microRNA-34c can enhance the detection sensitivity.
false
Yujia Liu
annotation2492780
1
anti-microRNA-34c
range2492780
1
110
132
annotation2492781
1
linker
range2492781
1
73
79
annotation2492782
1
linker
range2492782
1
43
49
annotation2492784
1
linker
range2492784
1
103
109
annotation2492776
1
anti-microRNA-34c
range2492776
1
50
72
annotation2492763
1
anti-microRNA-34c
range2492763
1
20
42
annotation2492777
1
anti-microRNA-34c
range2492777
1
80
102
BBa_K1940000_sequence
1
aagcttggtctcgctagaggcaatcagctaactacactgcctgggtcccgcaatcagctaactacactgcctgggtcccgcaatcagctaactacactgcctgggtcccgcaatcagctaactacactgccttactagcgagaccggtacc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z