BBa_R0011
1
lacI+pL
Promoter (lacI regulated, lambda pL hybrid)
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
represillator of Elowitz and Leibler (2000)
Released HQ 2013
Inverting regulatory region controlled by LacI (<bb_part>BBa_C0010</bb_part>, <bb_part>BBa_C0011</bb_part>, etc.) <p> The PLlac 0-1 promoter is a hybrid regulatory region consisting of the promoter P(L) of phage lambda with the cI binding sites replaced with lacO1. The hybrid design allows for strong promotion that can nevertheless be tightly repressed by LacI, the Lac inhibitor (i.e. repressor) (<bb_part>BBa_C0010</bb_part>) ([LUTZ97]). The activity of the promoter can be regulated over a >600-fold range by IPTG in E.Coli DH5-alpha-Z1 (same paper reference).
false
true
_1_
0
24
7
In stock
false
<P> <P>hybrid promoter design to create strong promoter that is, at the same time, highly repressible. note that the upstream operator installed in this hybrid is slightly different than the one in the original source (Lutz and Bujard, 1997). the most upstream operator region is slightly truncated in the represillator version, so that both operators in the hybrid are the same sequence. see references for details. also, the sequence has been truncated after the transcriptional start site.<P>LacI binds to this regulator. This part is incompatible with species containing active LacI coding regions. Lactose and IPTG disable the operation of LacI and increase transcription. This part is incompatible with environments containing lactose or lactose analogs.
true
Neelaksh Varshney, Grace Kenney, Daniel Shen, Samantha Sutton
annotation2001
1
lac O1
range2001
1
26
42
annotation1999
1
lac O1
range1999
1
3
19
annotation2002
1
-10
range2002
1
43
48
annotation7064
1
BBa_R0011
range7064
1
1
54
annotation2000
1
-35
range2000
1
20
25
BBa_K1952005
1
BBa_K1952005
Hydrazine Synthase subunit alpha (Kust-2861) with strong RBS
2016-10-18T11:00:00Z
2016-10-19T04:49:16Z
Taken from iGEM parts B0034 and K1952002
Protein coding region with translation initiation signals, to be used alone or in operon
false
false
_2419_
32346
32346
9
false
None
false
Jessica Zhao
component2522942
1
BBa_K1952002
component2522941
1
BBa_B0034
annotation2522941
1
BBa_B0034
range2522941
1
1
12
annotation2522942
1
BBa_K1952002
range2522942
1
19
2445
BBa_K1952002
1
BBa_K1952002
Hydrazine Synthase alpha subunit
2016-10-13T11:00:00Z
2016-10-29T09:32:31Z
hydrazine synthase subunit
hydrazine synthase subunit
false
false
_2419_
26856
33370
9
false
hydrazine synthase subunit
false
Alex Dean
BBa_K1952008
1
BBa_K1952008
Hydrazine Synthase subunit alpa (Kust-2861) with strong RBS under Lac promoter control
2016-10-18T11:00:00Z
2016-10-29T09:58:02Z
Hydrazine Synthase subunit alpa (Kust-2861) with strong RBS
Protein coding region with translation initiation signals, to be used alone or in operon
false
false
_2419_
26856
32346
9
false
none
false
Jessica Zhao
component2522976
1
BBa_R0011
component2522984
1
BBa_K1952005
annotation2522984
1
BBa_K1952005
range2522984
1
64
2508
annotation2522976
1
BBa_R0011
range2522976
1
1
54
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K1952002_sequence
1
atgggcaaacgcaaactgggcgtgattgcgagcgcgtttgtggcgggcgcgctggtgtgcggcagcaccctggtgaacgcggaaccggtgatgaccggcggcccggtgcagggcaaagcgctgtggaccgattatagcggcatgagcaaagaagtacagggtccagtgagccagattctgtttacccagagcccgcgcaccgcgaaaggcgatccgtatcagaactatccgcattatattccggaaggcagccgcattgtgctgtttgatctgaacaccaaagaactgaaagtgctgaccaacgattttgcgaccgccttcgacccatgcacctattgggatggcaaaaaatttgcgtttgcgggcgtgcataaaaaaggcggcggctgccaaatctgggaaatgaacattgatggcagcggcctgcgccagatgactgacctcaaaggcacctgccgcagcccgatttattatgcggcgggcagcattgaagaaggcgaaggccgaatcatttggcgcgatcgctattttgaaggggactggaaagaacatggcatggtggaaaaaaccggaatgattatttttagcggttcccctgagggggttatggatgaatttcataacccgtatgcgtataacctgtatcgcctggatacccagggcggcaaaattattcagcgcattaccggccatgttctatcaggtattgagtttccgcatttaaataccaccattgatcagattacctacaatctgagcagcaactttgatccgtggctgaccccggacgggaacatcctctttagcagcgtgcaggcgaacgggtcacgcgcgggcggggagggccgcgtgatgatctgcgtggataactgggacggcgcgtatccgcgcccaatatatggcaactgcgatggcgaaattggcggcaccagtggtcgcagccaagcaaaaattacctttggcgaccggaaaattgtgtatgtggaaagcccgtatatgaactggggcgtgggccagctggctgccgtgagctgggatgcgccgtttaacaaaacctatgaaaaactgactggtaaagatggcggtctttatcgtagtccgtaccctctgccggatgatcgcatgctggtgagctatgcggagcgaggcgacttcggcatttattggtttaacttctccaaatgcgcggccggagataaagtgtatgacgacccgaactggaacgatcatcagccggcgccggtatacgtgaaatataaaccgcgttggattaacacctttaccgcggggaagaacttcggagtgaccgtggtgacctatcaacctttcgaccaggtgaaggtagaaggctacccccatagctggggaacgtggatttgctttgatactactctgagcgatcaacccgtgggcccatatccacatcagaaagcgaaaaacgtatctcatggcgatattaaagcggtgcggataattcagggctatcagtgtgtagagcctgatagcacccgctttcgcgtcggggcgggtgcgcatctgctggggggcgagcgcagctccagtaacagcggcacagcctttcagcagcgcggcattattgggtatcagtacgtcgagtctgatggaagtaccgtgaccagccaactaagcgatgtgccgtattatatgcaaatcctggatgataaaggaatgtctgtccagaccgcgctgacctgggcttatctgcgcccctatcatggcaggatatgtagcggatgtcattatgggtcctatcgtgggcgcgcattcaaaaacattcatgctaaagcactgtataattggtggtacgatgatcgttctcactacgatagcccgttcgcatttcgctatctgaaatttgataacgacggaaactataaaggcgtgaaacacggtgaagatgtggtggtgccgagcgatatatactatggaggtccgagcggtactacgtcgcagccggtggaaggcctgacccttgacaaacagcgaacagtagactttcgccgcgatatccaaccgattctggatgcgaagtgcgctatgtgccatgactcaaacaacccgccgaacttaggtggtgggctggaattagttagcgttgacggcattgcggcgtatagccgcgcttataacagcctgctggaaccgcaacggggaaaggatccgaatatcggaggcaaatatgtgaacccgtcagctgccattaatagcctgttagtttggagactgtatgaagcggaactgagcgcgaacgcgccgcgcgaaaagatatttccgattgaggggcgcctactccataacaaatttctgacccaggatgaacgctacgccattgtggaatggattgacctcggggcacagtgggataacattccgggcccggatttttatccgggataccttgttaaa
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K1952005_sequence
1
aaagaggagaaatactagatgggcaaacgcaaactgggcgtgattgcgagcgcgtttgtggcgggcgcgctggtgtgcggcagcaccctggtgaacgcggaaccggtgatgaccggcggcccggtgcagggcaaagcgctgtggaccgattatagcggcatgagcaaagaagtacagggtccagtgagccagattctgtttacccagagcccgcgcaccgcgaaaggcgatccgtatcagaactatccgcattatattccggaaggcagccgcattgtgctgtttgatctgaacaccaaagaactgaaagtgctgaccaacgattttgcgaccgccttcgacccatgcacctattgggatggcaaaaaatttgcgtttgcgggcgtgcataaaaaaggcggcggctgccaaatctgggaaatgaacattgatggcagcggcctgcgccagatgactgacctcaaaggcacctgccgcagcccgatttattatgcggcgggcagcattgaagaaggcgaaggccgaatcatttggcgcgatcgctattttgaaggggactggaaagaacatggcatggtggaaaaaaccggaatgattatttttagcggttcccctgagggggttatggatgaatttcataacccgtatgcgtataacctgtatcgcctggatacccagggcggcaaaattattcagcgcattaccggccatgttctatcaggtattgagtttccgcatttaaataccaccattgatcagattacctacaatctgagcagcaactttgatccgtggctgaccccggacgggaacatcctctttagcagcgtgcaggcgaacgggtcacgcgcgggcggggagggccgcgtgatgatctgcgtggataactgggacggcgcgtatccgcgcccaatatatggcaactgcgatggcgaaattggcggcaccagtggtcgcagccaagcaaaaattacctttggcgaccggaaaattgtgtatgtggaaagcccgtatatgaactggggcgtgggccagctggctgccgtgagctgggatgcgccgtttaacaaaacctatgaaaaactgactggtaaagatggcggtctttatcgtagtccgtaccctctgccggatgatcgcatgctggtgagctatgcggagcgaggcgacttcggcatttattggtttaacttctccaaatgcgcggccggagataaagtgtatgacgacccgaactggaacgatcatcagccggcgccggtatacgtgaaatataaaccgcgttggattaacacctttaccgcggggaagaacttcggagtgaccgtggtgacctatcaacctttcgaccaggtgaaggtagaaggctacccccatagctggggaacgtggatttgctttgatactactctgagcgatcaacccgtgggcccatatccacatcagaaagcgaaaaacgtatctcatggcgatattaaagcggtgcggataattcagggctatcagtgtgtagagcctgatagcacccgctttcgcgtcggggcgggtgcgcatctgctggggggcgagcgcagctccagtaacagcggcacagcctttcagcagcgcggcattattgggtatcagtacgtcgagtctgatggaagtaccgtgaccagccaactaagcgatgtgccgtattatatgcaaatcctggatgataaaggaatgtctgtccagaccgcgctgacctgggcttatctgcgcccctatcatggcaggatatgtagcggatgtcattatgggtcctatcgtgggcgcgcattcaaaaacattcatgctaaagcactgtataattggtggtacgatgatcgttctcactacgatagcccgttcgcatttcgctatctgaaatttgataacgacggaaactataaaggcgtgaaacacggtgaagatgtggtggtgccgagcgatatatactatggaggtccgagcggtactacgtcgcagccggtggaaggcctgacccttgacaaacagcgaacagtagactttcgccgcgatatccaaccgattctggatgcgaagtgcgctatgtgccatgactcaaacaacccgccgaacttaggtggtgggctggaattagttagcgttgacggcattgcggcgtatagccgcgcttataacagcctgctggaaccgcaacggggaaaggatccgaatatcggaggcaaatatgtgaacccgtcagctgccattaatagcctgttagtttggagactgtatgaagcggaactgagcgcgaacgcgccgcgcgaaaagatatttccgattgaggggcgcctactccataacaaatttctgacccaggatgaacgctacgccattgtggaatggattgacctcggggcacagtgggataacattccgggcccggatttttatccgggataccttgttaaa
BBa_K1952008_sequence
1
aattgtgagcggataacaattgacattgtgagcggataacaagatactgagcacatactagagaaagaggagaaatactagatgggcaaacgcaaactgggcgtgattgcgagcgcgtttgtggcgggcgcgctggtgtgcggcagcaccctggtgaacgcggaaccggtgatgaccggcggcccggtgcagggcaaagcgctgtggaccgattatagcggcatgagcaaagaagtacagggtccagtgagccagattctgtttacccagagcccgcgcaccgcgaaaggcgatccgtatcagaactatccgcattatattccggaaggcagccgcattgtgctgtttgatctgaacaccaaagaactgaaagtgctgaccaacgattttgcgaccgccttcgacccatgcacctattgggatggcaaaaaatttgcgtttgcgggcgtgcataaaaaaggcggcggctgccaaatctgggaaatgaacattgatggcagcggcctgcgccagatgactgacctcaaaggcacctgccgcagcccgatttattatgcggcgggcagcattgaagaaggcgaaggccgaatcatttggcgcgatcgctattttgaaggggactggaaagaacatggcatggtggaaaaaaccggaatgattatttttagcggttcccctgagggggttatggatgaatttcataacccgtatgcgtataacctgtatcgcctggatacccagggcggcaaaattattcagcgcattaccggccatgttctatcaggtattgagtttccgcatttaaataccaccattgatcagattacctacaatctgagcagcaactttgatccgtggctgaccccggacgggaacatcctctttagcagcgtgcaggcgaacgggtcacgcgcgggcggggagggccgcgtgatgatctgcgtggataactgggacggcgcgtatccgcgcccaatatatggcaactgcgatggcgaaattggcggcaccagtggtcgcagccaagcaaaaattacctttggcgaccggaaaattgtgtatgtggaaagcccgtatatgaactggggcgtgggccagctggctgccgtgagctgggatgcgccgtttaacaaaacctatgaaaaactgactggtaaagatggcggtctttatcgtagtccgtaccctctgccggatgatcgcatgctggtgagctatgcggagcgaggcgacttcggcatttattggtttaacttctccaaatgcgcggccggagataaagtgtatgacgacccgaactggaacgatcatcagccggcgccggtatacgtgaaatataaaccgcgttggattaacacctttaccgcggggaagaacttcggagtgaccgtggtgacctatcaacctttcgaccaggtgaaggtagaaggctacccccatagctggggaacgtggatttgctttgatactactctgagcgatcaacccgtgggcccatatccacatcagaaagcgaaaaacgtatctcatggcgatattaaagcggtgcggataattcagggctatcagtgtgtagagcctgatagcacccgctttcgcgtcggggcgggtgcgcatctgctggggggcgagcgcagctccagtaacagcggcacagcctttcagcagcgcggcattattgggtatcagtacgtcgagtctgatggaagtaccgtgaccagccaactaagcgatgtgccgtattatatgcaaatcctggatgataaaggaatgtctgtccagaccgcgctgacctgggcttatctgcgcccctatcatggcaggatatgtagcggatgtcattatgggtcctatcgtgggcgcgcattcaaaaacattcatgctaaagcactgtataattggtggtacgatgatcgttctcactacgatagcccgttcgcatttcgctatctgaaatttgataacgacggaaactataaaggcgtgaaacacggtgaagatgtggtggtgccgagcgatatatactatggaggtccgagcggtactacgtcgcagccggtggaaggcctgacccttgacaaacagcgaacagtagactttcgccgcgatatccaaccgattctggatgcgaagtgcgctatgtgccatgactcaaacaacccgccgaacttaggtggtgggctggaattagttagcgttgacggcattgcggcgtatagccgcgcttataacagcctgctggaaccgcaacggggaaaggatccgaatatcggaggcaaatatgtgaacccgtcagctgccattaatagcctgttagtttggagactgtatgaagcggaactgagcgcgaacgcgccgcgcgaaaagatatttccgattgaggggcgcctactccataacaaatttctgacccaggatgaacgctacgccattgtggaatggattgacctcggggcacagtgggataacattccgggcccggatttttatccgggataccttgttaaa
BBa_R0011_sequence
1
aattgtgagcggataacaattgacattgtgagcggataacaagatactgagcaca
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z