BBa_K1964002
1
BBa_K1964002
FliC signal sequence
2016-10-13T11:00:00Z
2016-10-14T12:48:22Z
E. coli MG1655 gDNA
FliC encodes for Flagellin, the main compound of the E. coli flagellum. The 178bp FliC signal sequence directs it to the cell membrane, where it usually gets integrated.
In order to utilize this highly regulated mechanism, we generated a FliCD-knockout E. coli strain. This enabled us to fuse the signal sequence to the N-terminal end of our protein of interest, which as a result got exported and secreted into the medium.
false
false
_2431_
30038
30038
9
false
Requires the design of an E. coli strain where FliC and FliD are both knocked out.
false
Patrick Gerlinger
BBa_K1964002_sequence
1
cgggaataaggggcagagaaaagagtatttcggcgactaacaaaaaatggctgtttttgaaaaaaattctaaaggttgttttacgacagacgataacagggttgacggcgattgagccgacgggtggaaacccaatacgtaatcaacgacttgcaatataggataacgaatc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z