BBa_K1974003 1 BBa_K1974003 Orally Active Insecticidal Peptide (OAIP) 2016-10-12T11:00:00Z 2017-03-28T09:53:57Z Artificial Synthesis This year we create a revolutionary system that integrates biological pesticides, automatic detector, sprinkler, and IoT. We made a database that contains most of the spider toxins and selected the target toxins by programming. Orally Active Insecticidal Peptide is coded for the venom of a spider, Selenotypus plumipes. It is under the control of the strong T7 promoter. A 6xHistag is added for further protein purification. Mechanism of OAIP Orally Active Insecticidal Peptide has a structure called ICK(inhibitor cysteine knot). This kind of structure contains three disulfide bonds. With this structure OAIP can resist the high temperature, acid base solution and the digest juice of insect gut. OAIP can bind on the voltage-gated sodium channel in the insect???s nervous system, making it paralyze and die eventually. false false _2441_ 30645 30645 9 true It is under the control of the strong T7 promoter. A 6xHistag is added for further protein purification. false YU-CHUN WU BBa_K1974003_sequence 1 aaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaaa igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z