BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_S04537
1
BBa_S04537
K199199:J61046
2010-12-12T12:00:00Z
2015-05-08T01:14:41Z
false
false
_9_
0
5562
9
Not in stock
false
false
Mary Gearing
component2114991
1
BBa_K199199
component2114992
1
BBa_J61046
annotation2114991
1
BBa_K199199
range2114991
1
1
258
annotation2114992
1
BBa_J61046
range2114992
1
267
300
BBa_R0010
1
LacI
promoter (lacI regulated)
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
The Plac insert was PCR'd from the MG1655 strain of E.coli K12.
Released HQ 2013
Inverting regulatory region controlled by LacI (<bb_part>BBa_C0010</bb_part>, <bb_part>BBa_C0011</bb_part>, etc.) <p> The pLac regulatory region is a 243 base-pair sequence with standard BioBrick prefix and suffix sections on its ends. It contains two protein binding sites: CAP, which is generally present in E.coli and is assocciated with cell health and availability of glucose., and LacI, the Lac inhibitor <bb_part>BBa_C0010</bb_part> which binds in an dimerized cooperative manner to inhibit the transcription of the protein that follows. In the presence of lactose or IPTG, an analog of lactose, LacI is unable to correctly bind and inhibit transcription. This allows <bb_part>BBa_R0010</bb_part> to be used as a inverter or as a detector of lactose or IPTG.
false
true
_1_
0
24
7
In stock
false
<P> <P><P> LacI binds to this regulator. This part is incompatible with species containing active LacI coding regions. Lactose and IPTG disable the operation of LacI and this regulator. This part is incompatible with environments containing lactose or lactose analogs.
true
annotation1961222
1
BBa_R0010
range1961222
1
1
200
annotation1961226
1
LacI binding site
range1961226
1
166
200
annotation1961221
1
end of LacI coding region (inactive)
range1961221
1
1
88
annotation1961223
1
CAP binding site
range1961223
1
89
126
annotation1961224
1
-35
range1961224
1
137
142
annotation1961227
1
start
range1961227
1
173
173
annotation1961225
1
-10
range1961225
1
161
166
BBa_K199199
1
BBa_K199199
ATG-loxP-STOP sequence
2010-12-12T12:00:00Z
2015-05-08T01:11:21Z
loxP is J61042
Sequence also contains bidirectional transcriptional terminator B0014.
The stop sequence prevents transcription and translation. When excised, the downstream reporter genes (K199198 and K199197) are translated in frame.
false
false
_295_
0
5562
9
Not in stock
false
Designed to include multiple stop codons in all 6 reading frames.
false
Mary Gearing
BBa_J04500
1
BBa_J04500
IPTG inducible promoter with RBS
2005-06-08T11:00:00Z
2015-08-31T04:08:14Z
Davidson Synth-Aces
Released HQ 2013
R0010.B0034
false
true
_16_
0
326
16
In stock
false
false
Kristen DeCelle
component1508149
1
BBa_R0010
component1508159
1
BBa_B0034
annotation1508159
1
BBa_B0034
range1508159
1
209
220
annotation1508149
1
BBa_R0010
range1508149
1
1
200
BBa_K199200
1
BBa_K199200
pLac-RBS-ATG-loxP-STOP-loxP
2010-12-12T12:00:00Z
2015-05-08T01:11:21Z
See individual subparts.
When placed upstream of a reporter gene (K199197 or K199198), this sequence prevents expression of the gene. If the STOP sequence is excised, the reporter gene is excised.
false
false
_295_
0
5562
9
Not in stock
false
n/a
false
Mary Gearing
component2115004
1
BBa_S04537
component2115001
1
BBa_J04500
annotation2115001
1
BBa_J04500
range2115001
1
1
220
annotation2115004
1
BBa_S04537
range2115004
1
227
526
BBa_J61046
1
lox
[Lox] site for recombination
2007-02-20T12:00:00Z
2015-08-31T02:03:00Z
bob
Released HQ 2013
bob
false
false
_95_
0
483
95
In stock
false
bob
true
John Anderson
BBa_R0010_sequence
1
caatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacaca
BBa_B0034_sequence
1
aaagaggagaaa
BBa_J61046_sequence
1
ataacttcgtataatgtatgctatacgaagttat
BBa_J04500_sequence
1
caatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacacatactagagaaagaggagaaa
BBa_S04537_sequence
1
atgataacttcgtataatgtatgctatacgaagttataaggcctgattatgaagagcgtgtgacagagacacatagaatatctcacacgacatggcagttaaataataaaaaagccggattaataatctggctttttattattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagcgtgaactgccaatctgggttaagttatcttaggttttctgcaccgcgccttctttaatcaggcctttactagagataacttcgtataatgtatgctatacgaagttat
BBa_K199200_sequence
1
caatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacacatactagagaaagaggagaaatactagatgataacttcgtataatgtatgctatacgaagttataaggcctgattatgaagagcgtgtgacagagacacatagaatatctcacacgacatggcagttaaataataaaaaagccggattaataatctggctttttattattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagcgtgaactgccaatctgggttaagttatcttaggttttctgcaccgcgccttctttaatcaggcctttactagagataacttcgtataatgtatgctatacgaagttat
BBa_K199199_sequence
1
atgataacttcgtataatgtatgctatacgaagttataaggcctgattatgaagagcgtgtgacagagacacatagaatatctcacacgacatggcagttaaataataaaaaagccggattaataatctggctttttattattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagcgtgaactgccaatctgggttaagttatcttaggttttctgcaccgcgccttctttaatcaggcctt
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z