BBa_K2019005
1
BBa_K2019005
Periplasm Directed saCas9 via Ycdo Signaling Sequence (Ycdo-saCas9)
2016-10-11T11:00:00Z
2016-10-15T12:53:08Z
Ycdo came from the paper " "
Ycdo-Cas9 is a fusion of the Ycdo signaling sequence to the N-terminus of staphylococcus aureus CRISPR associated protein 9 (saCas9). Ycdo utilizes the sec pathway to direct the fused protein to the periplasm of the cell. Therefore, by fusing Cas9 to the C-terminus of the signaling sequence, it should be directed to the periplasm of the cell.
false
false
_2486_
31051
31051
9
false
Ycdo was ordered as a gblock with homology to the BBa_K2019000-BBa_R0040 expression system. BBa_K2019000-BBa_R0040 was linearized at the 5' end of saCas9. A 2 piece gibson assembly was then performed with the gblock and Cas9 expression backbone.
false
John Lazar
BBa_K2019005_sequence
1
atgaccattaacttccgccgtaacgcattgcagttgagcgtggctgcgctgttttcttctgcttttatggctaacgccgctgatgtgccgcaggtcaaaatgcaccaccatcatcatcatatgaagagaaattacattctgggattagatataggcattactagcgttgggtacggaataatcgactacgagacacgcgacgttatagacgctggcgtgcgcttgtttaaagaagctaatgtggaaaacaatgaagggagacgtagtaaacgcggtgcccgccgtttgaaaagaagacgccggcacagaatacagcgcgttaagaagttgcttttcgactataacttattgacagaccattcagagctttctggtataaacccctatgaagcacgcgttaagggactttctcagaagctttcggaagaagagttcagtgccgcattgttgcaccttgcaaagagacgtggtgtccacaacgtgaatgaggtcgaggaagacacagggaatgaattgtcaacaaaagaacagatatcacggaactcgaaagccctggaagaaaaatacgtcgccgagttacagctggagcggttgaagaaggacggtgaagtacggggttctataaatcggttcaaaaccagcgattacgtaaaagaagcgaagcagcttctgaaggtccagaaagcataccaccagctggaccaatctttcattgacacctatatagatctgcttgaaacacgcagaacttactatgagggtcccggagagggtagcccgttcggttggaaggatatcaaggaatggtatgaaatgttgatgggacactgtacatacttcccggaagaacttcggtcagtaaaatatgcatacaacgcagatctttacaatgccctgaatgatctgaataacttagtgatcacacgggacgagaatgaaaagttggagtactacgaaaagttccaaattattgaaaatgtgtttaagcaaaagaagaaacctacactgaagcaaattgccaaagagatcttagtcaacgaagaggacataaaaggttatcgcgtcacctcgaccggcaaacccgagttcaccaatttgaaggtttatcacgacataaaggacatcaccgcgagaaaagagatcatagagaacgcagagttactggaccagattgctaaaattttaaccatatatcagagtagcgaggacatacaggaagaattaacgaatcttaatagtgagcttacccaggaggagatcgagcaaatttcgaacctgaagggatatacaggcacacacaacctttcactgaaggcgataaatctgattttagacgaactgtggcacacaaacgacaatcaaattgccatattcaatcgtcttaagttggtgccgaaaaaagtcgatctgtcgcagcagaaggaaatccctacgaccttagtagatgattttatcttaagccccgtagttaagcgcagtttcattcaaagcataaaagtcataaatgcgatcatcaagaagtatgggcttccgaacgacataattatcgaattggctagagaaaagaactcgaaagatgcgcaaaagatgatcaacgagatgcaaaaacgcaaccggcagacgaacgagcgtattgaagagatcattagaaccacagggaaagaaaatgccaagtatctgatagagaagattaaattacacgacatgcaagaaggaaaatgcttgtatagtttggaggccatcccgcttgaggatctgttgaataatcctttcaactacgaggtggatcacataataccccgtagcgtttcattcgataattcttttaataataaggtacttgtcaagcaggaggagaatagtaaaaagggtaaccgcacgccatttcaatatttgtcctcgtctgattcgaaaatttcgtacgaaacctttaagaaacacattttgaacttggcaaaggggaaaggacggatttcaaaaacaaagaaggaataccttttggaagaacgcgacataaacagatttagcgtgcagaaagactttataaaccggaacttagttgacactcggtacgctacgcggggcttaatgaaccttttacggtcctacttccgggttaataatcttgatgtgaaagttaagagcataaatggtggatttacatcgtttttgcggcgtaaatggaaattcaagaaggagcggaataagggttataaacaccacgcagaagatgcccttataatagcgaacgcagattttatcttcaaggaatggaagaagctggataaggcgaagaaagtcatggagaatcagatgtttgaggaaaaacaagcagagagcatgccggaaatcgagacagagcaggagtataaagagatttttataactcctcaccaaataaagcatattaaagattttaaagattataaatattcacatagagtggataaaaaacccaatcgggaattaatcaatgacacgttgtatagtaccagaaaagacgataaggggaataccttaattgtcaacaatttaaacggcctgtacgacaaggataacgataaacttaaaaagctgatcaataaaagcccagaaaaattgctgatgtaccatcacgaccctcagacctaccaaaaattaaaattgattatggaacaatacggtgacgagaagaacccgttgtataaatattatgaagagacgggcaattatttaactaaatactcgaagaaggataacgggcccgtcattaagaagatcaaatactatggcaacaaattgaatgcacatcttgatataaccgatgattaccccaattcacgcaataaagtagtcaaactgtctttgaagccgtaccggtttgatgtttacttggataatggggtgtataagtttgtcacagtcaaaaacctggatgtcattaaaaaagaaaactactatgaagtgaatagtaaatgctacgaagaggcaaaaaagcttaaaaagataagcaatcaagcagaatttatagcaagtttctataataatgatcttattaaaataaacggcgaactttaccgcgtcataggggtgaataacgaccttcttaatagaatagaggtcaatatgatcgatattacataccgcgaatatttagaaaatatgaatgataagcgcccccctcgcattatcaagactatagcatccaagacgcagtccattaagaaatactccacggacatccttggcaacctttacgaagttaagtctaaaaaacatccgcagattattaaaaagggctga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z