BBa_K2040121
1
BBa_K2040121
PgpdA + KillerRed + TtrpC
2016-10-13T11:00:00Z
2016-10-19T09:45:49Z
BBa_K1184000
pBARGPE1
KillerRed was inserted between the gpdA promoter and trpC terminator on vector pBARGPE1.
false
false
_2507_
30360
30360
9
true
KillerRed can be replaced by KillerRed-NLS so that KillerRed can be localized in the nucleus.
false
Chilam Poon
component2512125
1
BBa_K1021010
component2512136
1
BBa_K2040120
annotation2512125
1
BBa_K1021010
range2512125
1
1
723
annotation2512136
1
BBa_K2040120
range2512136
1
730
1691
BBa_K2040120
1
BBa_K2040120
KillerRed + TtrpC
2016-10-11T11:00:00Z
2016-10-15T03:57:00Z
KillerRed was from BBa_K1184000.
TtrpC was isolated from fungal transformation vector pBARGPE1.
The phototoxic protein KillerRed(BBa_K1184000) was placed upstream the fungal terminator TtrpC(BBa_K1021008). Different kinds of fungal promoters with RBS can be added before this composite part to construct protein generators.
false
false
_2507_
30360
30360
9
false
aaa
false
Chilam Poon
component2512060
1
BBa_K1184000
annotation2512060
1
BBa_K1184000
range2512060
1
1
723
BBa_K1184000
1
BBa_K1184000
KillerRed
2013-09-03T11:00:00Z
2016-01-25T02:40:37Z
Engineered from avGFP. Provided by the Bruchez lab at Carnegie Mellon
KillerRed is a red fluorescent protein that produces reactive oxygen species (ROS) in the presence of yellow-orange light (540-585 nm). KillerRed is engineered from Aequorea victoria GFP (avGFP) to be phototoxic. It has been shown that KillerRed produces superoxide radical anions by reacting with water. Superoxide reacts with the chromophore of KillerRed, causing it to become dark, which ultimately gives rise to a bleaching effect. KillerRed is spectrally similar to mRFP1 with a similar brightness. KillerRed is oligomeric and may form large aggregates.
This sequence is codon optimized for mammalian cells and has 14 rare proline codons for E. coli (CCC) and one rare arginine codon (AGA). Codon optimization should be taken into consideration if large amounts of the protein are required. Expression on a high-copy plasmid has produced detectable fluorescent signal, however.
false
false
_1497_
4206
12713
9
In stock
true
This sequence is not codon optimized for E. coli.
false
Eric Pederson
annotation2334953
1
Double Stop
range2334953
1
718
723
annotation2334954
1
Start
range2334954
1
1
3
annotation2334965
1
Phototoxic Mutation Ala(163)
range2334965
1
487
489
annotation2334955
1
cds
range2334955
1
1
717
annotation2334958
1
Chromophore
range2334958
1
199
207
annotation2334960
1
Phototoxic Mutation Asn(147)
range2334960
1
439
441
annotation2334956
1
Phototoxic Mutation Glu(70)
range2334956
1
208
210
annotation2334957
1
Phototoxic Mutation Ser(121)
range2334957
1
367
369
BBa_K1021010
1
BBa_K1021010
PgpdA from A. nidulans
2013-09-12T11:00:00Z
2015-05-08T01:08:43Z
It was taken from pBARGPE1 from the Fungal Genetics Stock Center.
The strong constitutive promoter used to regulate the glyceraldehyde 3-phosphate dehydrogenase gene in Aspergillus nidulans.
false
false
_1328_
0
13516
9
In stock
false
The vector was unsequenced so we carried out several rounds of sequencing to determine the promoter sequence in order to be able to BioBrick it.
false
Swati Sureka
annotation2340062
1
PgpdA
range2340062
1
1
723
BBa_K2040121_sequence
1
gcatgcggagagacggacggacgcagagagaagggctgagtaataagcgccactgcgccagacagctctggcggctctgaggtgcagtggatgattattaatccgggaccggccgcccctccgccccgaagtggaaaggctggtgtgcccctcgttgaccaagaatctattgcatcatcggagaatatggagcttcatcgaatcaccggcagtaagcgaaggagaatgtgaagccaggggtgtatagccgtcggcgaaatagcatgccattaacctaggtacagaagtccaattgcttccgatctggtaaaagattcacgagatagtaccttctccgaagtaggtagagcgagtacccggcgcgtaagctccctaattggcccatccggcatctgtagggcgtccaaatatcgtgcctctcctgctttgcccggtgtatgaaaccggaaaggccgctcaggagctggccagcggcgcagaccgggaacacaagctggcagtcgacccatccggtgctctgcactcgacctgctgaggtccctcagtccctggtaggcagctttgccccgtctgtccgcccggtgtgtcggcggggttgacaaggtcgttgcgtcagtccaacatttgttgccatattttcctgctctccccaccagctgctcttttcttttctctttcttttcccatcttcagtatattcatcttcccatccaagaacctttatactagatgggttcagagggcggccccgccctgttccagagcgacatgaccttcaaaatcttcatcgacggcgaggtgaacggccagaagttcaccatcgtggccgacggcagcagcaagttcccccacggcgacttcaacgtgcacgccgtgtgcgagaccggcaagctgcccatgagctggaagcccatctgccacctgatccagtacggcgagcccttcttcgcccgctaccccgacggcatcagccatttcgcccaggagtgcttccccgagggcctgagcatcgaccgcaccgtgcgcttcgagaacgacggcaccatgaccagccaccacacctacgagctggacgacacctgcgtggtgagccgcatcaccgtgaactgcgacggcttccagcccgacggccccatcatgcgcgaccagctggtggacatcctgcccaacgagacccacatgttcccccacggccccaacgccgtgcgccagctggccttcatcggcttcaccaccgccgacggcggcctgatgatgggccacttcgacagcaagatgaccttcaacggcagccgcgccatcgagatccccggcccacacttcgtgaccatcatcaccaagcagatgagggacaccagcgacaagcgcgaccacgtgtgccagcgcgaggtggcctacgcccacagcgtgccccgcatcaccagcgccatcggtagcgacgaggattaataatactagaggcattgcagatgagctgtatctggaagaggtaaacccgaaacgcgttttattcttgttgacatggagctattaaatcactagaaggcactctttgctgcttggacaaatgaacgtatcttatcgagatcctgaacaccatttgtctcaactccggagctgacatcgacaccaacgatcttatatccagattcgtcaagctgtttgatgatttcagtaacgttaagtggatc
BBa_K1021010_sequence
1
gcatgcggagagacggacggacgcagagagaagggctgagtaataagcgccactgcgccagacagctctggcggctctgaggtgcagtggatgattattaatccgggaccggccgcccctccgccccgaagtggaaaggctggtgtgcccctcgttgaccaagaatctattgcatcatcggagaatatggagcttcatcgaatcaccggcagtaagcgaaggagaatgtgaagccaggggtgtatagccgtcggcgaaatagcatgccattaacctaggtacagaagtccaattgcttccgatctggtaaaagattcacgagatagtaccttctccgaagtaggtagagcgagtacccggcgcgtaagctccctaattggcccatccggcatctgtagggcgtccaaatatcgtgcctctcctgctttgcccggtgtatgaaaccggaaaggccgctcaggagctggccagcggcgcagaccgggaacacaagctggcagtcgacccatccggtgctctgcactcgacctgctgaggtccctcagtccctggtaggcagctttgccccgtctgtccgcccggtgtgtcggcggggttgacaaggtcgttgcgtcagtccaacatttgttgccatattttcctgctctccccaccagctgctcttttcttttctctttcttttcccatcttcagtatattcatcttcccatccaagaaccttta
BBa_K1184000_sequence
1
atgggttcagagggcggccccgccctgttccagagcgacatgaccttcaaaatcttcatcgacggcgaggtgaacggccagaagttcaccatcgtggccgacggcagcagcaagttcccccacggcgacttcaacgtgcacgccgtgtgcgagaccggcaagctgcccatgagctggaagcccatctgccacctgatccagtacggcgagcccttcttcgcccgctaccccgacggcatcagccatttcgcccaggagtgcttccccgagggcctgagcatcgaccgcaccgtgcgcttcgagaacgacggcaccatgaccagccaccacacctacgagctggacgacacctgcgtggtgagccgcatcaccgtgaactgcgacggcttccagcccgacggccccatcatgcgcgaccagctggtggacatcctgcccaacgagacccacatgttcccccacggccccaacgccgtgcgccagctggccttcatcggcttcaccaccgccgacggcggcctgatgatgggccacttcgacagcaagatgaccttcaacggcagccgcgccatcgagatccccggcccacacttcgtgaccatcatcaccaagcagatgagggacaccagcgacaagcgcgaccacgtgtgccagcgcgaggtggcctacgcccacagcgtgccccgcatcaccagcgccatcggtagcgacgaggattaataa
BBa_K2040120_sequence
1
atgggttcagagggcggccccgccctgttccagagcgacatgaccttcaaaatcttcatcgacggcgaggtgaacggccagaagttcaccatcgtggccgacggcagcagcaagttcccccacggcgacttcaacgtgcacgccgtgtgcgagaccggcaagctgcccatgagctggaagcccatctgccacctgatccagtacggcgagcccttcttcgcccgctaccccgacggcatcagccatttcgcccaggagtgcttccccgagggcctgagcatcgaccgcaccgtgcgcttcgagaacgacggcaccatgaccagccaccacacctacgagctggacgacacctgcgtggtgagccgcatcaccgtgaactgcgacggcttccagcccgacggccccatcatgcgcgaccagctggtggacatcctgcccaacgagacccacatgttcccccacggccccaacgccgtgcgccagctggccttcatcggcttcaccaccgccgacggcggcctgatgatgggccacttcgacagcaagatgaccttcaacggcagccgcgccatcgagatccccggcccacacttcgtgaccatcatcaccaagcagatgagggacaccagcgacaagcgcgaccacgtgtgccagcgcgaggtggcctacgcccacagcgtgccccgcatcaccagcgccatcggtagcgacgaggattaataatactagaggcattgcagatgagctgtatctggaagaggtaaacccgaaacgcgttttattcttgttgacatggagctattaaatcactagaaggcactctttgctgcttggacaaatgaacgtatcttatcgagatcctgaacaccatttgtctcaactccggagctgacatcgacaccaacgatcttatatccagattcgtcaagctgtttgatgatttcagtaacgttaagtggatc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z