BBa_K2062000 1 BBa_K2062000 Phosphoribosylaminoimidazole carboxylase catalytic subunit 2016-10-13T11:00:00Z 2016-10-25T01:41:45Z Strain: Brevibacillus brevis NBRC 100599 Function: phosphoribosylaminoimidazole carboxylase catalytic subunit This carboxylase is an enzyme involved in nucleotide biosynthesis, particularly in purine biosynthesis. It catalyzes the conversion of AIR (5???-phosphoribosyl-5-aminoimidazole) into CAIR (5???-phosphoribosyl-4-carboxy-5-aminoimidazole). 5-aminoimidazole ribonucleotide + CO2 5'-phosphoribosyl-4-carboxy-5-aminoimidazole + 2 H+ AIR synthetase is the fifth enzyme in the de novo synthesis of purine nucleotides. It catalyzes the reaction to form 5-aminoimidizole ribonucleotide (AIR) from formylglycinamidine-ribonucleotide FGAM. This reaction closes the ring and produces a 5-membered imidazole ring of the purine nucleus (AIR): false false _2530_ 32318 32318 9 false Temp false Jaeyoung Jung BBa_K2062000_sequence 1 ttaaaatgttcggaaacgaggttgacaggcaaactttctccctgctacactgaatacgttgagtgaaaacgagttcgaatagcccaggcgatgagagcggcgcgaaaagccgttagtcggttgggttttcttctgatgttacaaaacgtagggggcgaatggtttatgggtttgctagga igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z