BBa_K2068005
1
BBa_K2068005
O3-33 Wild Type
2016-09-12T11:00:00Z
2016-09-13T12:57:21Z
This cage is originally designed by Dr.Neil King.
The O3-33 gene codes for the production of one subunit of a protein cage. Each subunit consists of a trimeric protein that is designed to have low-energy protein-protein interfaces. Expression of this subunit will lead to the self assembly of a octahedral structured protein cage.Protein cages, are self assembling supramolecular protein structures where multiple protein subunits interact non covalently to form a higher order structure. This protein cage, O3-33, is a 24 subunit, 13nm diameter cage.
false
false
_2536_
27134
27134
9
false
This cage was computationally designed. The two steps that were crucial in the design of the cage were
1) symmetrical docking of protein building blocks in a target symmetric architecture
2) design of low energy protein-protein interfaces between the protein building blocks to drive self assembly.
false
Nithin Dharmaraj
BBa_K2068005_sequence
1
taatacgactcactatagggaaagaggagaaatactagatgagccaggcaattggtattctggaactgaccagcattgcagcaggtatggaactgggtgatgcaatgctgaaaagcgcgaacgtggatctgctggtgagcaaaaccattagcccgggtaaatttctgctgatgctgggcggtgatattggtgcgattcagcaggcgattgaaaccggtaccagccaggcgggcgaactgctggtggatagcctggtgctggcaaacattcatccgagcgtgctgccggcgattagcggtctgaacagcgtggataagcgtcaggcggtgggtattgtggaaacctggagcgtggcggcatgtattagcgcagcggatcgtgcggtgaagggtagcaacgtgaccctggtgcgtgtgcacatggcatttggtattggcggtaaatgttatatggtggtggcgggcgatgtgagcgatgtggcactggcggtgaccgtggcaagcagcagcgcaggcgcatacggtctgctggtgtatgcaagcctgattccgcgtccgcatgaagcaatgtggcgtcagatggtggaaggcctcgagcaccaccaccaccaccactga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z