BBa_K2088666
1
T
MhbT is responsible for the uptake of 3-hydroxybenzoate
2016-10-06T11:00:00Z
2016-10-08T03:01:00Z
We get the part from the bacteria M5a1, and the sequence of the gene was found through Genbank https://www.ncbi.nlm.nih.gov/nuccore/AY648560.1
MhbT is a transport protein which is located on the cytomembrane. It can transport the 3-HBA into the cell.By sequence comparison, MhbT exhibited 42% identity with the 4-hydroxybenzoate and protocatechuate transporter PcaK from P.putida, 27% identity with the benzoate transporter BenK from Acinetobacter sp. Using the MhbT-GFP fusion proteins , we can find that MhbT is located to the periphery of cells. It can be used in degradation system of 3-HBA, and can also be used in induction system whose derivant is 3-HBA.
false
false
_2556_
29893
29893
9
false
None
false
Shi Kejian
annotation2486847
1
MhbT coding region
range2486847
1
1
1359
annotation2486845
1
ATG start codon
range2486845
1
1
3
annotation2486846
1
TAA stop codon
range2486846
1
1357
1359
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation4184
1
stem_loop
range4184
1
12
55
annotation7018
1
BBa_B0010
range7018
1
1
80
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1686
1
T7 TE
range1686
1
8
27
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation7020
1
BBa_B0012
range7020
1
1
41
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_J23100
1
BBa_J23100
constitutive promoter family member
2006-08-03T11:00:00Z
2015-08-31T04:08:40Z
Isolated from library of promoters
Released HQ 2013
Replace later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_B0015
1
BBa_B0015
double terminator (B0010-B0012)
2003-07-16T11:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Double terminator consisting of BBa_B0010 and BBa_B0012
false
true
_1_
0
24
7
In stock
false
true
Reshma Shetty
component1916612
1
BBa_B0012
component1916610
1
BBa_B0010
annotation1916610
1
BBa_B0010
range1916610
1
1
80
annotation1916612
1
BBa_B0012
range1916612
1
89
129
BBa_K2088671
1
BBa_K2088671
J23100+B0034+mhbT+dT
2016-10-08T11:00:00Z
2016-10-14T08:56:44Z
This is a compostie part including a putative 3-hydroxybenzoate transporter gene(mhbT) from Klebsiella pneumoniae strain M5a1.
This composite part includes a constitutive promoter (BBa_J23100), a RBS(BBa_B0034), a putative 3-hydroxybenzoate transporter gene(mhbT) and the double terminator (BBa_B0015). The gene MhbT is a transport protein which is located on the cytomembrane. It can transport the 3-HBA into the cell.By sequence comparison. This composite part can be used in degradation system of 3-HBA, and can also be used in induction system whose derivant is 3-HBA.
false
false
_2556_
33751
33723
9
false
Uses J23100, a strong Anderson Promoter, to produce high levels of expression of mhbT.
false
Yuxin He
component2488831
1
BBa_K2088666
component2488827
1
BBa_B0034
component2488838
1
BBa_B0015
component2488825
1
BBa_J23100
annotation2488827
1
BBa_B0034
range2488827
1
44
55
annotation2488831
1
BBa_K2088666
range2488831
1
62
1420
annotation2488838
1
BBa_B0015
range2488838
1
1429
1557
annotation2488825
1
BBa_J23100
range2488825
1
1
35
BBa_J23100_sequence
1
ttgacggctagctcagtcctaggtacagtgctagc
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K2088671_sequence
1
ttgacggctagctcagtcctaggtacagtgctagctactagagaaagaggagaaatactagatgactcaacgacttgaattacagaagctgctcaacgccgcgccggtcggcgcccgacagtggcgcgtgattatctgctgtttcctggtggtgatgctcgatggctttgataccgccgcgattggttttatcgcgccggatatccgcagccactggcagctcaccgccggcgacctcgcgccgttatttggcgcgggattgctgggcctgaccgccggggcgctgctctgcggcccgctctccgaccgctttggccgcaaacgggtgattgagttttgcgtcgccctgttcggcctgttcagcctgctttccgcgtttgcccccgatctgcaaatgctggtgttcctgcgttttctgaccggcctcggcctcggcggcgcaatgcctaataccatcaccatgacctcggaatatttgcctgcccggcggcgcggggcgctggtaaccctgatgttttgcgggttcaccctcggttccgccttcggcggcgtggtcagcgcacagctggtgccgctgatcggctggcacggcattctggtgctcggcggcgttttaccgttgatactggcggtggcgctggtgcctctgcttcccgagtctccgcgctggcagatccgtcgccagctgccgcaggcgacgatcgccagaaccgtcggcgccattaccggcgagcgctataacgacacgcatttctggcttgatgaacctgccgcaggggcgaagggcagtatcagccagctgttcgccgggcgtcagttggccatcaccttaatgctatgggtggtgttctttatgagcctgctgattatctatctgctctccagctggatgccgacgttgctaaaccatcggggcattgatttacagcacgcttcgtgggtcaccgccgccttccagattggcggcacctttggcgcgctgctgctcggcgtgctgatggatcgcttcaatccctatcgggtgctggcgctgagctacggcctcggggcggtgtgtatcgtcatgattggcctgagcgagaacggcctgtggctgatggcgctggcgattttcggcaccggcatcggcatcagcggctcgcaggtggggctgaatgcgctaaccgcaacgctgtatcccacgcaaagccgcgcgactggcgtgagctggtcaaacgcggttggccgctgcggggccatcgttggctccctttccggcggtgtgatgatggcgatgaatttctcattcgataccctgttttttgttatcgccgtcccggccgttgtgagcgccgtgatgcttatcctgctgacgcttgccgtccgcaacccgacttctgtacccgccgcgctgccttccgcaggcattgtgaataaataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_K2088666_sequence
1
atgactcaacgacttgaattacagaagctgctcaacgccgcgccggtcggcgcccgacagtggcgcgtgattatctgctgtttcctggtggtgatgctcgatggctttgataccgccgcgattggttttatcgcgccggatatccgcagccactggcagctcaccgccggcgacctcgcgccgttatttggcgcgggattgctgggcctgaccgccggggcgctgctctgcggcccgctctccgaccgctttggccgcaaacgggtgattgagttttgcgtcgccctgttcggcctgttcagcctgctttccgcgtttgcccccgatctgcaaatgctggtgttcctgcgttttctgaccggcctcggcctcggcggcgcaatgcctaataccatcaccatgacctcggaatatttgcctgcccggcggcgcggggcgctggtaaccctgatgttttgcgggttcaccctcggttccgccttcggcggcgtggtcagcgcacagctggtgccgctgatcggctggcacggcattctggtgctcggcggcgttttaccgttgatactggcggtggcgctggtgcctctgcttcccgagtctccgcgctggcagatccgtcgccagctgccgcaggcgacgatcgccagaaccgtcggcgccattaccggcgagcgctataacgacacgcatttctggcttgatgaacctgccgcaggggcgaagggcagtatcagccagctgttcgccgggcgtcagttggccatcaccttaatgctatgggtggtgttctttatgagcctgctgattatctatctgctctccagctggatgccgacgttgctaaaccatcggggcattgatttacagcacgcttcgtgggtcaccgccgccttccagattggcggcacctttggcgcgctgctgctcggcgtgctgatggatcgcttcaatccctatcgggtgctggcgctgagctacggcctcggggcggtgtgtatcgtcatgattggcctgagcgagaacggcctgtggctgatggcgctggcgattttcggcaccggcatcggcatcagcggctcgcaggtggggctgaatgcgctaaccgcaacgctgtatcccacgcaaagccgcgcgactggcgtgagctggtcaaacgcggttggccgctgcggggccatcgttggctccctttccggcggtgtgatgatggcgatgaatttctcattcgataccctgttttttgttatcgccgtcccggccgttgtgagcgccgtgatgcttatcctgctgacgcttgccgtccgcaacccgacttctgtacccgccgcgctgccttccgcaggcattgtgaataaataa
BBa_B0015_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z