BBa_K2124001 1 BBa_K2124001 Venom Serine Protease from Cerastes Cerastes - Thrombin analog 2016-10-12T11:00:00Z 2016-10-28T04:15:06Z This is from a genomic sequence of Cerastes Cerastes. This Serine protease is a component of Cerastes Cerastes (Desert Horned Viper) venom. It recognizes Thrombin cut sites in fibrinogen and upon cleavage converts the fibrinogen to fibrin monomers. The fibrin monomers can then link and begin clot formation in mammals. false false _2593_ 28641 28641 9 false This protein is very small and stabilized by several disulfide bonds. The final construct will be secreted into the periplasmic space with DsbC, a protein that shuffles disfulfide bonds. DsbC will allow the Serine Protease to fold properly with correct disulfide bonding. This will give stable functional protein. false Brian Dempsey BBa_K2124001_sequence 1 gtaatcggcggggctgaatgtaacatcaacgaacatcgctctttagtcttgctttacaattcctcccgcttgtttggaggaggaaccttgattaataaagagtgggtattgtcagcagcgcactgtgacggcgagaatatgaaaatttacctgggactgcatcatttccgtttacccaacaaggatcgccagattcgtgtggcgaaggaaaagtatttttgtcgtgatcgcaaatctattgttgacaaagatatcatgttaatcaagctgaacaaaccagttaacaattctacacacattgctccgttaagtcttccctcaagtccaccctccgtcggaagtgactgccgtatcatgggatggggcaccatcaccagtccaaatgatacgtatcctaaagtccctcattgcgctaacatcaacatcttagagcatagtttgtgtgagcgcgcgtataacgatttgtctgcgtcctcacgcaccttgtgcgcgggaatcgagaaaggtggtatcgacacctgtaagggagacagcggcggaccgttgatttgtaacggccagatccaaggaattgtttcatggggtgacgaggtttgcggaaaacctaataagcctggtgtatatactaaagtattcgactacacggactggattcgtaacattatcgccggaaacactgccgcgacttgcccgcag igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z