BBa_K2124002
1
BBa_K2124002
Venom Serine Protease from Cerastes Cerastes - Thrombin analog
2016-10-12T11:00:00Z
2016-10-13T08:19:23Z
This is from a genomic sequence.
This Serine protease is a component of Cerastes Cerastes (Desert Horned Viper) venom. It recognizes Thrombin cut sites in fibrinogen and upon cleavage converts the fibrinogen to fibrin monomers. The fibrin monomers can then link and begin clot formation in mammals. This part contains a medium constitutive promoter and a secretion tag to send it to the periplasmic space.
false
false
_2593_
28641
28641
9
false
This protein is very small and stabilized by several disulfide bonds. The final construct will be secreted into the periplasmic space with DsbC, a protein that shuffles disfulfide bonds. DsbC will allow the Serine Protease to fold properly with correct disulfide bonding. This will give stable functional protein.
false
Brian Dempsey
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z