BBa_R0082
1
OmpR
Promoter (OmpR, positive)
2004-01-27T12:00:00Z
2015-05-08T01:14:15Z
NC_000193 E. coli K12
Released HQ 2013
Positively regulated, OmpR-controlled promoter. This promoter is taken from the upstream region of ompC. Phosphorylated OmpR binds to the three operator sites and activates transcription.
false
false
_1_
0
24
7
In stock
false
The promoter includes the three OmpR binding sites: C1, C2, and C3. The promoter starts at -107 and goes up to the transcriptional start site at +1.
An alternate version, BBa_R0083, cuts out the C2 and C3 sites.
The efficacy of this promoter versus the truncated ompC upstream region (BBa_R0083) or the ompF upstream region (BBa_R0084) is currently unknown.
true
Stephen Lee, Roshan Kumar, Joe Levine, Ziyan Chu (Polkadorks, IAP 2004)
annotation301156
1
C3 OmpR
range301156
1
54
71
annotation301167
1
-10
range301167
1
98
103
annotation301166
1
-35
range301166
1
75
80
annotation301154
1
C1 OmpR
range301154
1
13
30
annotation301155
1
C2 OmpR
range301155
1
34
51
BBa_K216010
1
BBa_K216010
ompC promoter with lacZ
2009-10-15T11:00:00Z
2015-05-08T01:11:30Z
Made by joining ompC promoter BBa_R0082 to lacZ' reporter J33202.
This is the ompC promoter, controlled by response-regulator OmpR and sensor kinase EnvZ; attached to a lacZ' reporter gene for Miller assay.
false
false
_317_
0
837
163
It's complicated
true
No special considerations.
false
Edinburgh iGEM 2009
component2047033
1
BBa_J33202
component2047030
1
BBa_R0082
annotation2047030
1
BBa_R0082
range2047030
1
1
108
annotation2047033
1
BBa_J33202
range2047033
1
117
359
BBa_J33202
1
BBa_J33202
lacZ
2006-10-12T11:00:00Z
2015-08-31T04:08:46Z
The DNA was derived by PCR from E. coli BL21, which possesses an intact lacZ gene. Primers were designed based on sequence from GenBank accession J01636, GI:146575. A stop codon was artificially introduced to replace codon 78. The sequence reported here is derived by sequencing of the Biobrick construct.
Released HQ 2013
This gene encodes the N-terminal 77 amino acid residues of LacZ. When expressed in an E. coli host carrying the lacZ-delta-M15 mutation, common in laboratory strains, it complements the delection resulting in the production of active LacZ, which can be detected by various means, including chromogenic substrates such as Xgal (5-bromo-4-chloro-3-indolyl-beta-D-galactoside) and ONPG (o-nitrophenyl galactoside).
false
false
_63_
0
837
63
In stock
true
Note that a stop codon was introduced to replace codon 78 of lacZ, resulting in production only of the N-terminal 77 amino acid residues of LacZ. This is sufficient to complement the lacZ-delta-M15 mutation commonly found in laboratory strains of E. col used for alpha-complementation.
false
Chris French
annotation1902818
1
rbs
range1902818
1
1
4
annotation1902819
1
lacZ'
range1902819
1
13
243
BBa_K216010_sequence
1
tcccttgcatttacattttgaaacatctatagcgataaatgaaacatcttaaaagttttagtatcatattcgtgttggattattctgcatttttggggagaatggacttactagaggaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
BBa_J33202_sequence
1
gaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
BBa_R0082_sequence
1
tcccttgcatttacattttgaaacatctatagcgataaatgaaacatcttaaaagttttagtatcatattcgtgttggattattctgcatttttggggagaatggact
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z