BBa_K243001
1
Fok_i
Protein domain (inactive) of the restriction endonuclease FokI
2009-10-07T11:00:00Z
2015-05-08T01:11:37Z
extract coding region of Fok from the restriction-modification genes of the chromosomal DNA of Flavobacterium okeanokoites. Part synthesized by Mr.Gene
This part is used as the inactive domain of our universal restriction endonuclease. It fused with the active protein domain of our universal restriction endonuclease(BBa_K243000)and linked with specific oligos.
false
false
_352_
0
4732
9
It's complicated
true
Modifications of the vector (catalytic inactive heterodimer)
-heterodimeric amino acids
* switch Glutamin 486/298-300 to Glutamate (CAA->GAA)
* switch Isoleucin 499/337-339 to Leucin (ATC->CTG)
-catalytic amino acids
* switch Aspartate 450/190-192 to Alanin (GAC->GCG)
* switch Aspartate 467/243-245 to Alanin (GAT->GCG)
false
Freiburg Bioware09
annotation2041872
1
Fok_i
range2041872
1
1
579
BBa_K243006
1
LongLinker
Long Linker (Gly-Gly-Ser-Gly)x3
2009-10-13T11:00:00Z
2015-05-08T01:11:37Z
Oligos synthesized by sigma. Hybridized by PCR.
This part is a linker, it can be used to connect two parts and add additional space between these parts. That can be necessary to avoid interactions between these parts. We used this part to connect our protein domains with our lipocalin domains, for our project the universal endonuclease.The sequence produced the aminoacids Gly-Gly-Ser-Gly-Gly-Gly-Ser-Gly-Gly-Gly-Ser-Gly.
false
false
_352_
0
4732
9
It's complicated
false
None.
false
Freiburg Bioware09
annotation2041937
1
Long Linker
range2041937
1
1
36
BBa_K243009
1
LongLinker
Long Linker-Fok_i
2009-10-13T11:00:00Z
2015-05-08T01:11:37Z
Combinated by cloning.
This part is the combination of the parts BBa_K243006(Long Linker) and the part BBa_K243001(the protein domain Foka). These combination allows a direct coupling of the protein domain to another part e.g. a tag for purification. The linker can secure a independent function of the protein domain when it is linked to another part.
false
false
_352_
0
4732
9
It's complicated
false
The length of the linker is important to guarantee the independent function of the protein domain when it is linked two another part.
false
Freiburg Bioware09
component2055753
1
BBa_K243006
component2055755
1
BBa_B0105
component2055757
1
BBa_K243001
annotation2055757
1
BBa_K243001
range2055757
1
43
621
annotation2055755
1
BBa_B0105
range2055755
1
37
42
annotation2055753
1
BBa_K243006
range2055753
1
1
36
BBa_B0105
1
Scar 25
RFC 25 Scar Sequence
2009-10-14T11:00:00Z
2015-08-31T04:07:21Z
BBF RFC 25
This is the scar produced by assembly using RFC 25.
If you are assembling a composite part using RFC 25, you can insert this part and specify blunt assembly to get the desired sequence.
false
false
_1_
0
25
397
Not in stock
false
Simple DNA sequence
false
Randy Rettberg
annotation2041621
1
Scar 25
range2041621
1
1
6
BBa_B0105_sequence
1
accggc
BBa_K243001_sequence
1
aaatctgaactggaggagaaaaaatccgagctgcgccacaaactgaaatatgtgcctcacgagtatatcgaactgatcgagatcgcccgtaatagtacccaagaccgtatcctggaaatgaaagtgatggagttcttcatgaaagtctatggctatcgtggcaaacatctgggtggtagccgtaaaccagcaggtgccatttataccgttggttccccgatcgattatggcgttatcgtggccacaaaagcgtattctggcggttataatctgccgattggtcaggctgatgagatggaacgttatgtggaagagaatcagacccgtaacaaacatctgaacccgaacgaatggtggaaagtgtatccgtcaagtgtcaccgagttcaaatttctgttcgtgagcggccactttaaaggcaactataaagcccagctgactcgtctgaaccatatcaccaatagcaatggggcagtgctgagtgttgaggaactgctgatcggtggagaaatgatcaaagcaggcaccctgactctggaagaagttcgccgtaaattcaacaatggcgagatcaatttt
BBa_K243006_sequence
1
ggtggttctggtggtggttctggtggtggttctggt
BBa_K243009_sequence
1
ggtggttctggtggtggttctggtggtggttctggtaccggcaaatctgaactggaggagaaaaaatccgagctgcgccacaaactgaaatatgtgcctcacgagtatatcgaactgatcgagatcgcccgtaatagtacccaagaccgtatcctggaaatgaaagtgatggagttcttcatgaaagtctatggctatcgtggcaaacatctgggtggtagccgtaaaccagcaggtgccatttataccgttggttccccgatcgattatggcgttatcgtggccacaaaagcgtattctggcggttataatctgccgattggtcaggctgatgagatggaacgttatgtggaagagaatcagacccgtaacaaacatctgaacccgaacgaatggtggaaagtgtatccgtcaagtgtcaccgagttcaaatttctgttcgtgagcggccactttaaaggcaactataaagcccagctgactcgtctgaaccatatcaccaatagcaatggggcagtgctgagtgttgaggaactgctgatcggtggagaaatgatcaaagcaggcaccctgactctggaagaagttcgccgtaaattcaacaatggcgagatcaatttt
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z