BBa_K243025
1
BBa_K243025
Strep-FluA-Middle Linker-Fok_i
2009-10-17T11:00:00Z
2015-05-08T01:11:37Z
Combined by serial clonig steps.
This combination of parts use the benefits of an Strep-tag and is linked with a FluroescineA tag. The MiddleLinker (GlySerGlyGly)x2 produce a certain distance between the FluA tag and the protein domain Fok_i.
false
false
_352_
0
4732
9
It's complicated
false
The linker length and the choice of the purification tag in combination with the anticalin tag allowed us several combination possibilities, which we had to prove to achieve the best combination.
false
Freiburg Bioware09
component2051378
1
BBa_K243001
component2051372
1
BBa_B0105
component2051376
1
BBa_B0105
component2051374
1
BBa_K243005
component2051366
1
BBa_K157012
component2051370
1
BBa_K157004
component2051368
1
BBa_B0105
annotation2051374
1
BBa_K243005
range2051374
1
559
582
annotation2051372
1
BBa_B0105
range2051372
1
553
558
annotation2051378
1
BBa_K243001
range2051378
1
589
1167
annotation2051366
1
BBa_K157012
range2051366
1
1
24
annotation2051368
1
BBa_B0105
range2051368
1
25
30
annotation2051376
1
BBa_B0105
range2051376
1
583
588
annotation2051370
1
BBa_K157004
range2051370
1
31
552
BBa_K157012
1
BBa_K157012
Strep affinity tag II; Freiburg standard
2008-10-25T11:00:00Z
2015-05-08T01:10:54Z
Gene synthesis by ATG:biosynthetics, optimized for expression in homo sapiens by iGEM-Team Freiburg 2008.
Strep tag as NgoMIV / AgeI protein fusion part, fusion to proteins facilitates detection, purification, immobilization.
false
false
_232_
0
1673
9
It's complicated
false
Between BioBrick 1.0 sites this part is flanked 5' by NgoMI(=NgoMIV) and 3' AgeI(=PinAI) to facilitate in frame cloning for protein fusions.
true
Kristian M??ller
annotation2041866
1
Strep-Tag II
range2041866
1
1
24
annotation2041865
1
Strep-Tag II
range2041865
1
1
24
BBa_K243001
1
Fok_i
Protein domain (inactive) of the restriction endonuclease FokI
2009-10-07T11:00:00Z
2015-05-08T01:11:37Z
extract coding region of Fok from the restriction-modification genes of the chromosomal DNA of Flavobacterium okeanokoites. Part synthesized by Mr.Gene
This part is used as the inactive domain of our universal restriction endonuclease. It fused with the active protein domain of our universal restriction endonuclease(BBa_K243000)and linked with specific oligos.
false
false
_352_
0
4732
9
It's complicated
true
Modifications of the vector (catalytic inactive heterodimer)
-heterodimeric amino acids
* switch Glutamin 486/298-300 to Glutamate (CAA->GAA)
* switch Isoleucin 499/337-339 to Leucin (ATC->CTG)
-catalytic amino acids
* switch Aspartate 450/190-192 to Alanin (GAC->GCG)
* switch Aspartate 467/243-245 to Alanin (GAT->GCG)
false
Freiburg Bioware09
annotation2041872
1
Fok_i
range2041872
1
1
579
BBa_K243005
1
MiddleLink
Middle Linker ( Gly-Gly-Ser-Gly)x2
2009-10-13T11:00:00Z
2015-05-08T01:11:37Z
Oligos synthesized by sigma. Hybridized by PCR.
This part is a linker, it can be used to connect two parts and add additional space between these parts. That can be necessary to avoid interactions between these parts. We used this part to connect our protein domains with our lipocalin domains, for our project the universal endonuclease.The sequence produced the aminoacids Gly-Gly-Ser-Gly-Gly-Gly-Ser-Gly .
false
false
_352_
0
4732
9
It's complicated
false
None.
false
Freiburg Bioware09
annotation2041884
1
MiddleLinker
range2041884
1
1
24
BBa_K157004
1
BBa_K157004
Fluoresceine-A-binding
2008-10-25T11:00:00Z
2015-05-08T01:10:54Z
Gene synthesis by GeneArt, optimized for expression in homo sapiens.
Fluoresceine A -binding derivative of a Lipocalin (BBP, bilin binding protein from pieris brassicae), originally designed by Arne Skerra [see Ref. 1,2].
false
false
_232_
0
1673
9
It's complicated
false
Between BioBrick 1.0 sites this part is flanked 5' by NgoMI(=NgoMIV) and 3' AgeI(=PinAI) to facilitate in frame cloning for protein fusions.
false
iGEM Team Freiburg 2008
annotation2040659
1
Lipocalin FluA
range2040659
1
1
522
BBa_B0105
1
Scar 25
RFC 25 Scar Sequence
2009-10-14T11:00:00Z
2015-08-31T04:07:21Z
BBF RFC 25
This is the scar produced by assembly using RFC 25.
If you are assembling a composite part using RFC 25, you can insert this part and specify blunt assembly to get the desired sequence.
false
false
_1_
0
25
397
Not in stock
false
Simple DNA sequence
false
Randy Rettberg
annotation2041621
1
Scar 25
range2041621
1
1
6
BBa_B0105_sequence
1
accggc
BBa_K157012_sequence
1
tggagccatccgcagtttgaaaaa
BBa_K243005_sequence
1
ggtggttctggtggtggttctggt
BBa_K243001_sequence
1
aaatctgaactggaggagaaaaaatccgagctgcgccacaaactgaaatatgtgcctcacgagtatatcgaactgatcgagatcgcccgtaatagtacccaagaccgtatcctggaaatgaaagtgatggagttcttcatgaaagtctatggctatcgtggcaaacatctgggtggtagccgtaaaccagcaggtgccatttataccgttggttccccgatcgattatggcgttatcgtggccacaaaagcgtattctggcggttataatctgccgattggtcaggctgatgagatggaacgttatgtggaagagaatcagacccgtaacaaacatctgaacccgaacgaatggtggaaagtgtatccgtcaagtgtcaccgagttcaaatttctgttcgtgagcggccactttaaaggcaactataaagcccagctgactcgtctgaaccatatcaccaatagcaatggggcagtgctgagtgttgaggaactgctgatcggtggagaaatgatcaaagcaggcaccctgactctggaagaagttcgccgtaaattcaacaatggcgagatcaatttt
BBa_K243025_sequence
1
tggagccatccgcagtttgaaaaaaccggcgacgtgtaccacgacggcgcctgccccgaagtgaagcccgtggacaacttcgactggtcccagtaccacggcaagtggtgggaggtggccaagtaccccagccccaacggcaagtatggcaagtgcggctgggccgagtacacccccgagggcaagagcgtgaaggtgtccagatacgacgtgatccacggcaaagaatacttcatggaaggcaccgcctaccccgtgggcgacagcaagatcggcaagatctaccacagccggaccgtgggcggctacaccagaaagaccgtgttcaacgtgctgtccaccgacaacaagaactacatcatcggctacagctgccgctacgacgaggacaagaagggccactgggaccacgtgtgggtgctgtcccggtccatggtgctgaccggcgaggccaagaccgccgtggagaactacctgatcggcagccccgtggtggacagccagaaactggtgtacagcgacttcagcgaggccgcctgcaaagtgaacaacaccggcggtggttctggtggtggttctggtaccggcaaatctgaactggaggagaaaaaatccgagctgcgccacaaactgaaatatgtgcctcacgagtatatcgaactgatcgagatcgcccgtaatagtacccaagaccgtatcctggaaatgaaagtgatggagttcttcatgaaagtctatggctatcgtggcaaacatctgggtggtagccgtaaaccagcaggtgccatttataccgttggttccccgatcgattatggcgttatcgtggccacaaaagcgtattctggcggttataatctgccgattggtcaggctgatgagatggaacgttatgtggaagagaatcagacccgtaacaaacatctgaacccgaacgaatggtggaaagtgtatccgtcaagtgtcaccgagttcaaatttctgttcgtgagcggccactttaaaggcaactataaagcccagctgactcgtctgaaccatatcaccaatagcaatggggcagtgctgagtgttgaggaactgctgatcggtggagaaatgatcaaagcaggcaccctgactctggaagaagttcgccgtaaattcaacaatggcgagatcaatttt
BBa_K157004_sequence
1
gacgtgtaccacgacggcgcctgccccgaagtgaagcccgtggacaacttcgactggtcccagtaccacggcaagtggtgggaggtggccaagtaccccagccccaacggcaagtatggcaagtgcggctgggccgagtacacccccgagggcaagagcgtgaaggtgtccagatacgacgtgatccacggcaaagaatacttcatggaaggcaccgcctaccccgtgggcgacagcaagatcggcaagatctaccacagccggaccgtgggcggctacaccagaaagaccgtgttcaacgtgctgtccaccgacaacaagaactacatcatcggctacagctgccgctacgacgaggacaagaagggccactgggaccacgtgtgggtgctgtcccggtccatggtgctgaccggcgaggccaagaccgccgtggagaactacctgatcggcagccccgtggtggacagccagaaactggtgtacagcgacttcagcgaggccgcctgcaaagtgaacaac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z