BBa_K257017
1
FecI
Fec I, part of the signal transduction pathway FecARI
2009-10-17T11:00:00Z
2015-05-08T01:11:41Z
For more information, see: Gene regulation by transmembrane signaling. Volkmar Braun et al., 2006
The fec transduction pathway is unique because it allows a signal to be passed from the extracellular milieu down to the cytoplasm, thus being transmitted through both the outer and inner membrane. Briefly, the outermembrane protein FecA binds ferric citrate, change its conformation to interact with FecR which is an transmembrane protein located in the inner membrane. Then FecR is able to activate FecI an alternative sigma factor specific to Pfec.
In some variant of the system, the activated FecR homologues would repress FecI activity instead of activating it.
false
false
_354_
0
5130
9
It's complicated
false
Fec I needs to be expressed in association with Fec R behind the Pfec promoter in order to have a functional transduction pathway.
false
Soufiane Boumahdi
annotation2057839
1
good rbs
range2057839
1
1
8
annotation2057840
1
fecI
range2057840
1
14
532
annotation2057841
1
double codon stop
range2057841
1
533
538
BBa_K257017_sequence
1
aaggaggtatataatgtctgaccgcgccactaccacagcttccttaacgttcgagtcgctttatggcacacatcacggctggttgaaaagctggctgacgcgcaaactccagtctgcttttgatgcagatgacattgcccaggacacttttttgcgggtaatggtcagcgaaacgctctcgacgatccgcgatcctcgctccttcctctgcactatcgccaaacgcgtgatggtggacctgtttcgccgaaacgcgctggaaaaagcgtatctggagatgctggcgcttatgccggaggggggagcgccttcacctgaggaacgcgaaagccaactcgagaccctacaactcctcgacagcatgctggacgggctaaacggcaaaacacgtgaagcgtttctgctttcgcaactggatggtctgacatacagcgagattgcgcacaaactcggtgtttccatcagctccgtgaaaaaatacgtggcgaaagccgtcgagcactgcctgctgttccgtctggagtatgggttataataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z