BBa_K289002
1
BBa_K289002
GSH
2009-10-20T11:00:00Z
2015-05-08T01:11:49Z
synthesised
According to the Toxicity mechanism, Adda binding site of MCs has a strong affinity to the lyophobic groove of PP1. Also, according to the Detoxicity mechanism, GSH could construct a covalent bond with Mdha banding site of MCs easily under the function of GST(Glutathione S-Transferase Agents which presents in the cell of Yeast)
In our project, we connect PP1 gene after DNA-BD in the plasmid pGBKT7 and GSH gene after AD in the plasmid pGADT7, and then we transform these two plasmids into Yeast(AH109) so that it can express protein DNA-BD-PP1 and AD-GSH. At last our hero MCs enters. It will connect with AD-GSH which has a system can lead it to the nucleus of yeast, and then AD-GSH-MCs comes into the core to connect with DNA-BD-PP1 on chromosome.
false
false
_393_
0
4781
9
No part sequence
false
accoding to the protein of the MCs,we design it .
false
Nan Hou
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z