BBa_I11030
1
BBa_I11030
integrase from E. coli phage P22
2004-09-02T11:00:00Z
2015-08-31T04:07:30Z
Nuc Acid Res, 2001; 29(11):2205-2216
P22 Integrase with LVA tag
false
false
_2_
0
102
7
It's complicated
false
false
mschomp
annotation1126751
1
LVA
range1126751
1
1162
1194
annotation1126806
1
stop
range1126806
1
1195
1200
annotation2214028
1
Help:Barcodes
range2214028
1
1201
1225
annotation1126718
1
Integrase p22
range1126718
1
1
1161
BBa_B1006
1
BBa_B1006
Terminator (artificial, large, %T~>90)
2006-08-30T11:00:00Z
2015-08-31T04:07:21Z
modified E. coli thr terminator, replaced all A-T pairs in stem with C-G pairs
Released HQ 2013
Artificial terminator, estimated %T~>90%
*8bp stem, 6nt loop
*Bidirectional, estimated reverse %T~>90%
false
true
_41_
0
745
41
In stock
false
Bidirectional, with the reverse estimated to be less effective than the forward. Has a polyA tail of 9 residues.
true
Haiyao Huang
annotation1898429
1
modified thr terminator
range1898429
1
10
31
annotation1898431
1
PolyA
range1898431
1
1
9
annotation1898430
1
PolyA
range1898430
1
32
39
annotation1898428
1
B1006
range1898428
1
1
39
BBa_R0011
1
lacI+pL
Promoter (lacI regulated, lambda pL hybrid)
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
represillator of Elowitz and Leibler (2000)
Released HQ 2013
Inverting regulatory region controlled by LacI (<bb_part>BBa_C0010</bb_part>, <bb_part>BBa_C0011</bb_part>, etc.) <p> The PLlac 0-1 promoter is a hybrid regulatory region consisting of the promoter P(L) of phage lambda with the cI binding sites replaced with lacO1. The hybrid design allows for strong promotion that can nevertheless be tightly repressed by LacI, the Lac inhibitor (i.e. repressor) (<bb_part>BBa_C0010</bb_part>) ([LUTZ97]). The activity of the promoter can be regulated over a >600-fold range by IPTG in E.Coli DH5-alpha-Z1 (same paper reference).
false
true
_1_
0
24
7
In stock
false
<P> <P>hybrid promoter design to create strong promoter that is, at the same time, highly repressible. note that the upstream operator installed in this hybrid is slightly different than the one in the original source (Lutz and Bujard, 1997). the most upstream operator region is slightly truncated in the represillator version, so that both operators in the hybrid are the same sequence. see references for details. also, the sequence has been truncated after the transcriptional start site.<P>LacI binds to this regulator. This part is incompatible with species containing active LacI coding regions. Lactose and IPTG disable the operation of LacI and increase transcription. This part is incompatible with environments containing lactose or lactose analogs.
true
Neelaksh Varshney, Grace Kenney, Daniel Shen, Samantha Sutton
annotation2001
1
lac O1
range2001
1
26
42
annotation1999
1
lac O1
range1999
1
3
19
annotation2002
1
-10
range2002
1
43
48
annotation7064
1
BBa_R0011
range7064
1
1
54
annotation2000
1
-35
range2000
1
20
25
BBa_K200021
1
BBa_K200021
pLacI+RBS
2009-10-14T11:00:00Z
2015-05-08T01:11:21Z
Both parts from the Registry
Promoter for the LacI gene ligated to a RBS
false
false
_298_
0
5155
9
It's complicated
false
N/A
false
Royah Vaezi
component2041376
1
BBa_B0034
component2041370
1
BBa_R0011
annotation2041370
1
BBa_R0011
range2041370
1
1
54
annotation2041376
1
BBa_B0034
range2041376
1
64
75
BBa_K318013
1
BBa_K318013
T + pLac + RBS + Int (P22) + T
2010-07-12T11:00:00Z
2015-05-08T01:11:57Z
Biobricks
This composite part is an inducible P22 Int integrase generator which acts on the P22 attB and attP recombination sites. It is composed of the following biobricks: BBa_B1006, BBa_K200021, BBa_I11030, BBa_B1006.
false
false
_438_
0
4845
9
Not in stock
false
To minimize potential transcription due to upstream promoter activity, a terminator was placed upstream of the pLac promoter. A terminator was placed downstream of the Int encoding sequence to end transcription after the recombinase is produced. Note that to fully repress the pLac promoter, overproduction of the lacI repressor protein is necessary.
false
Nathaniel Pantalone, Justin Vrana
component2257274
1
BBa_K200021
component2257284
1
BBa_B1006
component2257266
1
BBa_B1006
component2257279
1
BBa_I11030
annotation2257266
1
BBa_B1006
range2257266
1
1
39
annotation2257279
1
BBa_I11030
range2257279
1
129
1353
annotation2257284
1
BBa_B1006
range2257284
1
1362
1400
annotation2257274
1
BBa_K200021
range2257274
1
48
122
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_B0034_sequence
1
aaagaggagaaa
BBa_B1006_sequence
1
aaaaaaaaaccccgcccctgacagggcggggtttttttt
BBa_K200021_sequence
1
aattgtgagcggataacaattgacattgtgagcggataacaagatactgagcacatactagagaaagaggagaaa
BBa_R0011_sequence
1
aattgtgagcggataacaattgacattgtgagcggataacaagatactgagcaca
BBa_I11030_sequence
1
atgtcactattccgcagaggtgaaacctggtacgccagtttcacattgccgaacggcaaaagatttaagcagtctcttgggacaaaggacaaaaggcaggccacagagcttcatgacaagctgaaggcagaagcatggagggtaagtaaattaggagagacgcctgacatgacttttgagggggcctgtgtcaggtggttagaggagaaggcgcataagaagtcgctggatgatgacaagagtcggataggattctggctccagcattttgcaggaatgcagttgaaggatattaccgagacgaagatttactccgccatccagaagataactaatcggcggcatgaggaaaactggaagttaatggatgaagcatgcaggaagaatgggaagcagcctccggtattcaagcctaagccggcagcagtagctacaaaagcaactcacctttcattcattaaggcactcctccgggctgctgaacgcgaatggaagatgctggataaggctccgatcatcaaagttcctcagccgaaaaataagcgtatccgctggcttgagcctcacgaggcaaaaaggttgattgatgaatgccaggaaccgctaaagtcagtcgtagagtttgcgctttctactggcttaaggcggtctaacattatcaatctggagtggcagcagatagacatgcaacgaaaggtggcatggatacacccggaacaaagcaagtctaatcatgccattggagtggcgctgaatgataccgcttgccgggtgctgaaaaagcaaatcggcaatcatcacaaatgggtgttcgtctacaaggaaagcagcaccaaaccagacggaactaaatcacctgtagtgaggaagatgcgctatgacgctaatactgcatggagggcagcattaaaacgagcgggcattgaagacttccgttttcatgacctgaggcacacgtgggcaagttggttagttcaggctggcgttccgatttcggtattgcaggaaatgggtggctgggagtctatcgaaatggttcgccgatatgctcatctggcaccaaatcacctgactgaacatgctcgacaaattgactcgatttttggtacttctgtcccaaatatgtcccacagtaaaaataaggaaggcacgaataatacggcagcaaacgacgaaaactacgctttagtagcttaataaccctgatagtgctagtgtagatccc
BBa_K318013_sequence
1
aaaaaaaaaccccgcccctgacagggcggggtttttttttactagagaattgtgagcggataacaattgacattgtgagcggataacaagatactgagcacatactagagaaagaggagaaatactagatgtcactattccgcagaggtgaaacctggtacgccagtttcacattgccgaacggcaaaagatttaagcagtctcttgggacaaaggacaaaaggcaggccacagagcttcatgacaagctgaaggcagaagcatggagggtaagtaaattaggagagacgcctgacatgacttttgagggggcctgtgtcaggtggttagaggagaaggcgcataagaagtcgctggatgatgacaagagtcggataggattctggctccagcattttgcaggaatgcagttgaaggatattaccgagacgaagatttactccgccatccagaagataactaatcggcggcatgaggaaaactggaagttaatggatgaagcatgcaggaagaatgggaagcagcctccggtattcaagcctaagccggcagcagtagctacaaaagcaactcacctttcattcattaaggcactcctccgggctgctgaacgcgaatggaagatgctggataaggctccgatcatcaaagttcctcagccgaaaaataagcgtatccgctggcttgagcctcacgaggcaaaaaggttgattgatgaatgccaggaaccgctaaagtcagtcgtagagtttgcgctttctactggcttaaggcggtctaacattatcaatctggagtggcagcagatagacatgcaacgaaaggtggcatggatacacccggaacaaagcaagtctaatcatgccattggagtggcgctgaatgataccgcttgccgggtgctgaaaaagcaaatcggcaatcatcacaaatgggtgttcgtctacaaggaaagcagcaccaaaccagacggaactaaatcacctgtagtgaggaagatgcgctatgacgctaatactgcatggagggcagcattaaaacgagcgggcattgaagacttccgttttcatgacctgaggcacacgtgggcaagttggttagttcaggctggcgttccgatttcggtattgcaggaaatgggtggctgggagtctatcgaaatggttcgccgatatgctcatctggcaccaaatcacctgactgaacatgctcgacaaattgactcgatttttggtacttctgtcccaaatatgtcccacagtaaaaataaggaaggcacgaataatacggcagcaaacgacgaaaactacgctttagtagcttaataaccctgatagtgctagtgtagatccctactagagaaaaaaaaaccccgcccctgacagggcggggtttttttt
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z