BBa_K322117
1
BBa_K322117
phoA promoter and lacZ reporter
2010-10-26T11:00:00Z
2015-05-08T01:11:59Z
phoA promoter: Escherichia coli K12
lacZ reporter: Escherichia coli K12
This biobrick regulated by the PhoR-PhoB two component system. This part can thus be used test the green light sensor in a "Coliroid" fashion, when grown with Xgal.
false
false
_441_
0
6225
9
Not in stock
false
no
false
William Rostain and Meng Lu
component2109213
1
BBa_K322115
component2109216
1
BBa_J33202
annotation2109213
1
BBa_K322115
range2109213
1
1
160
annotation2109216
1
BBa_J33202
range2109216
1
169
411
BBa_K322115
1
BBa_K322115
phoA promoter
2010-10-26T11:00:00Z
2015-05-08T01:11:59Z
phoA: Escherichia coli K12
This part is the upstream region (150 bases) of E. coli phoA. In the green light sensor system, it is used to activate the expression of downstream parts. It is also regulated by the PhoR-PhoB two component system.
false
false
_441_
0
6225
9
Not in stock
false
The 150 bases upstream of the phoA gene were amplified to include the promoter.
false
Meng Lu and William Rostain
BBa_J33202
1
BBa_J33202
lacZ
2006-10-12T11:00:00Z
2015-08-31T04:08:46Z
The DNA was derived by PCR from E. coli BL21, which possesses an intact lacZ gene. Primers were designed based on sequence from GenBank accession J01636, GI:146575. A stop codon was artificially introduced to replace codon 78. The sequence reported here is derived by sequencing of the Biobrick construct.
Released HQ 2013
This gene encodes the N-terminal 77 amino acid residues of LacZ. When expressed in an E. coli host carrying the lacZ-delta-M15 mutation, common in laboratory strains, it complements the delection resulting in the production of active LacZ, which can be detected by various means, including chromogenic substrates such as Xgal (5-bromo-4-chloro-3-indolyl-beta-D-galactoside) and ONPG (o-nitrophenyl galactoside).
false
false
_63_
0
837
63
In stock
true
Note that a stop codon was introduced to replace codon 78 of lacZ, resulting in production only of the N-terminal 77 amino acid residues of LacZ. This is sufficient to complement the lacZ-delta-M15 mutation commonly found in laboratory strains of E. col used for alpha-complementation.
false
Chris French
annotation1902818
1
rbs
range1902818
1
1
4
annotation1902819
1
lacZ'
range1902819
1
13
243
BBa_J33202_sequence
1
gaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
BBa_K322117_sequence
1
gacgatacggagctgctgcgcgattacgtaaagaagttattgaagcatcctcgtcagtaaaaagttaatcttttcaacagctgtcataaagttgtcacggccgagacttatagtcgctttgtttttattttttaatgtatttgtacatggagaaaataaatactagaggaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
BBa_K322115_sequence
1
gacgatacggagctgctgcgcgattacgtaaagaagttattgaagcatcctcgtcagtaaaaagttaatcttttcaacagctgtcataaagttgtcacggccgagacttatagtcgctttgtttttattttttaatgtatttgtacatggagaaaataaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z