BBa_K364309 1 BBa_K364309 Human ER LBD 2010-09-28T11:00:00Z 2015-05-08T01:12:14Z Human ER (of the nuclear hormone receptor superfamily) Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol(estrogen). member of the nuclear hormone family of intracellular receptors. false false _486_ 0 6778 9 It's complicated true The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25 false Lior Malka BBa_K364307 1 BBa_K364307 Human ER DBD 2010-09-27T11:00:00Z 2015-05-08T01:12:14Z Human ER(of the nuclear hormone receptor superfamily) Estrogen receptor refers to a group of receptors that are activated by the hormone 17β-estradiol[1] (estrogen) , which is a member of the nuclear hormone family of intracellular receptors. The main function of the estrogen receptor is as a DNA-binding transcription factor that regulates gene expression. false false _486_ 0 6778 9 It's complicated true The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25 false Lior Malka annotation2096966 1 Zinc Finger (cys2/his2) range2096966 1 148 220 annotation2093923 1 Zinc Finger (cys2/his2) range2093923 1 43 100 BBa_K364329 1 BBa_K364329 ER DBD-VDR hinge-ER LBD 2010-10-19T11:00:00Z 2015-05-08T01:12:15Z Human VDR hinge, ER DBD and LBD. Estrogen receptor DBD - Vitamin D receptor hinge region - Estrogen receptor LBD false false _486_ 0 6885 9 It's complicated true Compatible with RFC-10 and RFC-25. false Endre K??roly Krist??f component2096970 1 BBa_K364312 component2096969 1 BBa_K364307 component2096971 1 BBa_K364309 annotation2096970 1 BBa_K364312 range2096970 1 249 533 annotation2096971 1 BBa_K364309 range2096971 1 542 1294 annotation2096969 1 BBa_K364307 range2096969 1 1 240 BBa_K364312 1 BBa_K364312 Human VDR hinge region 2010-09-29T11:00:00Z 2015-05-08T01:12:14Z Human VDR (of the nuclear hormone receptor superfamily) the vitamin D receptor (VDR) and also known as NR1I1 (nuclear receptor subfamily 1, group I, member 1), is a member of the nuclear receptor family of transcription factors. Upon activation by vitamin D, the VDR forms a heterodimer with the retinoid-X receptor and binds to hormone response elements on DNA resulting in expression or transrepression of specific geneproducts. In humans, the vitamin D receptor is encoded by the VDR gene. Hinge region: Thought to be a flexible domain that connects the DBD with the LBD. Influences intracellular trafficking and subcellular distribution. false false _486_ 0 6778 9 It's complicated true The reconstruction of the DBD to the hinge region and LBD will be done with RFC 25. false Lior Malka BBa_K364307_sequence 1 aagggcagcatggccatggaaagcgccaaagagacacggtactgcgccgtgtgcaacgactacgccagcggctaccactacggcgtgtggtcctgcgagggctgcaaggccttcttcaagcggagcatccagggccacaacgactacatgtgccccgccaccaaccagtgcaccatcgacaagaaccggcggaagtcctgccaggcctgtcggctgcggaagtgctacgaagtgggcatg BBa_K364309_sequence 1 agcaagaagaacagcctggccctgagcctgaccgccgaccagatggtgtccgccctgctcgacgccgagccccctatcctgtacagcgagtacgaccccacccggcccttcagcgaggcctctatgatgggcctgctgaccaacctggccgaccgcgagctggtgcacatgatcaactgggccaagcgggtgcccggcttcgtggacctgaccctgcacgaccaggtccacctcctggaatgcgcctggctggaaatcctgatgatcggcctggtctggcggagcatggaacaccccggcaagctgctgttcgcccccaacctgctgctggaccggaaccagggcaaatgcgtggaaggcatggtggaaatcttcgacatgctgctggctacaagcagccggttccggatgatgaacctccagggcgaagagttcgtgtgcctgaagtccatcatcctgctgaacagcggcgtgtacaccttcctgagcagcaccctgaagtccctggaagagaaggaccacatccaccgggtgctggacaagatcaccgacaccctgatccacctcatggccaaggctggcctgacactccagcaacagcaccagagactggcccagctcctgctgatcctgagccacatccggcacatgagcaacaagggaatggaacacctgtacagcatgaagtgcaagaacgtggtgcccctgtacgatctgctcctggaaatgctggacgcccaccggcttcatgcc BBa_K364312_sequence 1 gatgaagaagtgcagcggaagcgcgagatgatcctgaagcggaaagaggaagaggccctgaaggacagcctgcggcccaagctgagcgaggaacagcagcggatcattgccatcctgctggacgcccaccacaagacctacgaccccacctacagcgatttctgccagttcagaccccccgtgcgcgtgaacgatggcggcggaagccacccctctcggcccaatagcagacacacccccagcttcagcggcgacagcagctctagctgtagcgaccactgtatc BBa_K364329_sequence 1 aagggcagcatggccatggaaagcgccaaagagacacggtactgcgccgtgtgcaacgactacgccagcggctaccactacggcgtgtggtcctgcgagggctgcaaggccttcttcaagcggagcatccagggccacaacgactacatgtgccccgccaccaaccagtgcaccatcgacaagaaccggcggaagtcctgccaggcctgtcggctgcggaagtgctacgaagtgggcatgtactagaggatgaagaagtgcagcggaagcgcgagatgatcctgaagcggaaagaggaagaggccctgaaggacagcctgcggcccaagctgagcgaggaacagcagcggatcattgccatcctgctggacgcccaccacaagacctacgaccccacctacagcgatttctgccagttcagaccccccgtgcgcgtgaacgatggcggcggaagccacccctctcggcccaatagcagacacacccccagcttcagcggcgacagcagctctagctgtagcgaccactgtatctactagagagcaagaagaacagcctggccctgagcctgaccgccgaccagatggtgtccgccctgctcgacgccgagccccctatcctgtacagcgagtacgaccccacccggcccttcagcgaggcctctatgatgggcctgctgaccaacctggccgaccgcgagctggtgcacatgatcaactgggccaagcgggtgcccggcttcgtggacctgaccctgcacgaccaggtccacctcctggaatgcgcctggctggaaatcctgatgatcggcctggtctggcggagcatggaacaccccggcaagctgctgttcgcccccaacctgctgctggaccggaaccagggcaaatgcgtggaaggcatggtggaaatcttcgacatgctgctggctacaagcagccggttccggatgatgaacctccagggcgaagagttcgtgtgcctgaagtccatcatcctgctgaacagcggcgtgtacaccttcctgagcagcaccctgaagtccctggaagagaaggaccacatccaccgggtgctggacaagatcaccgacaccctgatccacctcatggccaaggctggcctgacactccagcaacagcaccagagactggcccagctcctgctgatcctgagccacatccggcacatgagcaacaagggaatggaacacctgtacagcatgaagtgcaagaacgtggtgcccctgtacgatctgctcctggaaatgctggacgcccaccggcttcatgcc igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z