BBa_K364308 1 BBa_K364308 Human PXR LBD 2010-09-27T11:00:00Z 2015-05-08T01:12:14Z Human PXR(of the nuclear hormone receptor superfamily) Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by naturally occurring steroids, such as pregnenolone and progesterone. false false _486_ 0 6778 9 It's complicated true The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25 false Bence Daniel BBa_K364319 1 BBa_K364319 Gal4 DBD 2010-10-07T11:00:00Z 2015-05-08T01:12:14Z Regulatory protein This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which encode for the enzymes used to convert galactose to glucose. This protein contains a fungal Zn(2)-Cys(6) binuclear cluster domain. false false _486_ 0 6778 9 It's complicated true The reconstruction of the DBD to the hinge region, LBD and Backbone will be done with RFC 25 false Lior Malka BBa_K364304 1 BBa_K364304 TRE-CMV 2010-08-12T11:00:00Z 2015-05-08T01:12:14Z Arteficial The Tetracycline Response Element (TRE) is recognized and bound by the Tetracycline repressor (TetR) protein. The TRE consists of 7 repeats separated by spacer sequences and placed upstream of CMV minimal promoter that has basal expession in the abscence of bound TetR. Tetracycline derivatives (e.g. doxycycline) bind TetR and render it incapable of binding to TRE, thereby forcing the expression of target genes. false false _486_ 0 6885 9 It's complicated true Compatible with RFC-25 and RFC-10. false Endre K??roly Krist??f annotation2077761 1 TRE range2077761 1 1 249 annotation2077762 1 minimal P-CMV range2077762 1 255 315 annotation2077768 1 6th tetO range2077768 1 187 205 annotation2077763 1 1st tetO range2077763 1 9 27 annotation2077764 1 2nd tetO range2077764 1 45 63 annotation2077766 1 4th tetO range2077766 1 116 134 annotation2077769 1 7th tetO range2077769 1 223 241 annotation2077765 1 3rd tetO range2077765 1 80 98 annotation2077767 1 5th tetO range2077767 1 152 170 BBa_K364302 1 BBa_K364302 PolyA 2010-08-10T11:00:00Z 2015-05-08T01:12:14Z Arteficial The PolyA tail of mRNA has multiple adenilates which is important for the nuclear export, translation and stability of mRNA in eukaryotes. false false _486_ 0 6885 9 It's complicated true Compatible with RFC-10 and RFC-25. false Endre K??roly Krist??f BBa_K364332 1 BBa_K364332 TRE-Gal4-PXR-PolyA in PSB1A3 (expression vector) 2010-10-19T11:00:00Z 2015-05-08T01:12:15Z Arteficial and human PXR LBD. Expression vector from standard BioBrick parts, epressing Gal4 - human Pregnane X receptor LBD composite part. false false _486_ 0 6885 9 It's complicated true Compatible with RFC-10 and RFC-25. false Endre K??roly Krist??f component2090765 1 BBa_K364319 component2090764 1 BBa_K364304 component2090766 1 BBa_K364308 component2090767 1 BBa_K364302 annotation2090767 1 BBa_K364302 range2090767 1 1519 1709 annotation2090764 1 BBa_K364304 range2090764 1 1 321 annotation2090766 1 BBa_K364308 range2090766 1 779 1510 annotation2090765 1 BBa_K364319 range2090765 1 330 770 BBa_K364332_sequence 1 tcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttatccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgaggtaggcgtgtacggtgggaggcctatataagcagagctcgtttagtgaaccgtcagatcgcctggatactagaggccaagctactgtcttctatcgaacaagcatgcgatatttgccgacttaaaaagctcaagtgctccaaagaaaaaccgaagtgcgccaagtgtctgaagaacaactgggagtgtcgctactctcccaaaaccaaaaggtctccgctgactagggcacatctgacagaagtggaatcaaggctagaaagactggaacagctatttctactgatttttcctcgagaagaccttgacatgattttgaaaatggattctttacaggatataaaagcattgttaacaggattatttgtacaagataatgtgaataaagatgccgtcacagatagattggcttcagtggagactgatatgcctctaacattgagacagcatagaataagtgcgacatcatcatcggaagagagtagtaacaaaggtcaaagacagttgactgtatcgtactagagcccagccgggaagaggccgccaagtggtcccaggtccgcaaggacctgtgcagcctgaaggtgtccctccagctcagaggcgaggacggcagcgtgtggaactacaagccccctgccgacagcggcggcaaagagatcttcagcctgctgccccacatggccgacatgagcacctacatgttcaagggcatcatcagcttcgccaaagtgatcagctacttccgggacctgcccatcgaggaccagatctccctgctgaagggcgctgccttcgagctgtgccagctccggttcaacaccgtgttcaacgccgagacaggcacctgggagtgcggcagactgagctactgcctggaagataccgctggcggctttcaacagctcctgctggaacccatgctgaagttccactacatgctgaagaagctccagctccacgaagaggaatacgtgctgatgcaggccatcagcctgttcagccccgacagacccggcgtgctccagcatagagtggtggaccagctccaggaacagttcgccatcaccctgaagtcctacatcgagtgcaaccggccccagcccgcccatcggtttctgtttctgaagatcatggccatgctgaccgagctgcggagcatcaacgcccagcacacccagcggctgctgcggatccaggacatccaccccttcgccacccccctgatgcaggaactgtttggaatcaccggcagctactagagggatcataatcagccataccacatttgtagaggttttacttgctttaaaaaacctcccacacctccccctgaacctgaaacataaaatgaatgcaattgttgttgttaacttgtttattgcagcttataatggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcct BBa_K364304_sequence 1 tcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttatccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgaggtaggcgtgtacggtgggaggcctatataagcagagctcgtttagtgaaccgtcagatcgcctgga BBa_K364319_sequence 1 gccaagctactgtcttctatcgaacaagcatgcgatatttgccgacttaaaaagctcaagtgctccaaagaaaaaccgaagtgcgccaagtgtctgaagaacaactgggagtgtcgctactctcccaaaaccaaaaggtctccgctgactagggcacatctgacagaagtggaatcaaggctagaaagactggaacagctatttctactgatttttcctcgagaagaccttgacatgattttgaaaatggattctttacaggatataaaagcattgttaacaggattatttgtacaagataatgtgaataaagatgccgtcacagatagattggcttcagtggagactgatatgcctctaacattgagacagcatagaataagtgcgacatcatcatcggaagagagtagtaacaaaggtcaaagacagttgactgtatcg BBa_K364302_sequence 1 ggatcataatcagccataccacatttgtagaggttttacttgctttaaaaaacctcccacacctccccctgaacctgaaacataaaatgaatgcaattgttgttgttaacttgtttattgcagcttataatggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcct BBa_K364308_sequence 1 cccagccgggaagaggccgccaagtggtcccaggtccgcaaggacctgtgcagcctgaaggtgtccctccagctcagaggcgaggacggcagcgtgtggaactacaagccccctgccgacagcggcggcaaagagatcttcagcctgctgccccacatggccgacatgagcacctacatgttcaagggcatcatcagcttcgccaaagtgatcagctacttccgggacctgcccatcgaggaccagatctccctgctgaagggcgctgccttcgagctgtgccagctccggttcaacaccgtgttcaacgccgagacaggcacctgggagtgcggcagactgagctactgcctggaagataccgctggcggctttcaacagctcctgctggaacccatgctgaagttccactacatgctgaagaagctccagctccacgaagaggaatacgtgctgatgcaggccatcagcctgttcagccccgacagacccggcgtgctccagcatagagtggtggaccagctccaggaacagttcgccatcaccctgaagtcctacatcgagtgcaaccggccccagcccgcccatcggtttctgtttctgaagatcatggccatgctgaccgagctgcggagcatcaacgcccagcacacccagcggctgctgcggatccaggacatccaccccttcgccacccccctgatgcaggaactgtttggaatcaccggcagc igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 James Alastair McLaughlin Chris J. Myers 2017-03-06T15:00:00.000Z