BBa_K415200
1
BBa_K415200
Strong Constitutive T5 Promoter with cmt Operator (T5-cmt)
2010-08-19T11:00:00Z
2015-05-08T01:12:27Z
This part was synthesized via minigene construction by Mr. Gene; its source is the 2010 paper by Choi, et al., titled, "A novel, versatile, and tightly regulated expression system for E. Coli strains."
This is a strong, constitutive partial T5 promoter with the cmt operator appended immediately
afterward. This construct was specified in a recent (as of 2010) paper by Choi, et al., titled, "A
novel, versatile, and tightly regulated expression system for E. Coli strains." In the absence
of cymR, this promoter should function as a strong, constitutive promoter; in the presence of
cymR, this promoter should be repressed with essentially zero leaky transcription.
true
false
_525_
0
6719
9
Discontinued
false
This promoter contains the T5 partial promoter, the sequence of which was derived from the 2010 Choi, et al. paper. Like T7 bacteriophage promoters, this T5 promoter is constitutive and strong; unlike T7 promoters, however, it does not require T7 RNA Polymerase. This means that the T5 promoter could have wide applicability as a strong promoter in Escherichia coli and other organisms.
false
Grant Robinson
annotation2078428
1
cmt Operator
range2078428
1
54
85
annotation2078429
1
T5 Partial Promoter
range2078429
1
1
53
BBa_K415201
1
BBa_K415201
B0015 : T5-cmt (Terminator : T5-cmt Promoter)
2010-08-19T11:00:00Z
2015-05-08T01:12:27Z
This part comes from BioBricks BBa_B0015 and BBa_K415200.
This is a terminator followed by a copy of the cmt operator downstream of a partial T5 promoter.
This part is an intermediate part that will could be used in order to ensure leaky expression from
components preceding the T5-cmt promoter does not interfere with the activity of the T5-cmt
promoter or any subsequent parts. This composite part consists of BioBricks BBa_K415200 and
BBa_B0015.
true
false
_525_
0
6719
9
Discontinued
false
No design considerations.
false
Grant Robinson
component2078430
1
BBa_B0010
component2078438
1
BBa_K415200
component2078432
1
BBa_B0012
annotation2078438
1
BBa_K415200
range2078438
1
138
222
annotation2078430
1
BBa_B0010
range2078430
1
1
80
annotation2078432
1
BBa_B0012
range2078432
1
89
129
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation4184
1
stem_loop
range4184
1
12
55
annotation7018
1
BBa_B0010
range7018
1
1
80
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation1686
1
T7 TE
range1686
1
8
27
annotation1687
1
stop
range1687
1
34
34
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1690
1
polya
range1690
1
28
41
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K415200_sequence
1
aaatcataaaaaatttatttgctttgtgagcggataacaattataatagattcaacaaacagacaatctggtctgtttgtattat
BBa_K415201_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttatatactagagaaatcataaaaaatttatttgctttgtgagcggataacaattataatagattcaacaaacagacaatctggtctgtttgtattat
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z