BBa_K592008
1
PT5lac
T5-lac Promoter
2011-09-10T11:00:00Z
2015-05-08T01:12:48Z
Phage T5
Released HQ 2013
T5-lac promoter is a hybrid promoter made from the phage T5 early promoter and lac-operon. It contains three LacI binding sites and remains repressed in LacIq strains where LacI is expressed in high levels. It is inducible by IPTG, and recognizable by E.coli RNA polymerase. Compared to the T7 promoters, T5-lac promoter doesn't require the co-expression of phage polymerase.
false
false
_763_
0
7929
9
In stock
false
The most common DH5alpha and TOP10 used in assembly are not LacI-constitutive (LacIq) strains. Thus, any ORF placed downstream to this promoter will be massively transcribed. Therefore, it's recommended to employ low-copy number plasmids or even LacIq strains when adding genes to this promoter.
false
Erik Lundin
annotation2135658
1
lacOi site
range2135658
1
94
123
annotation2135659
1
-35 signal
range2135659
1
63
68
annotation2127135
1
T5-lac promoter
range2127135
1
1
126
annotation2135656
1
lacO1 site
range2135656
1
1
26
annotation2135657
1
lacO1 site
range2135657
1
69
86
annotation2135661
1
-10 signal
range2135661
1
87
93
BBa_K592008_sequence
1
tgtggaattgtgagcggataacaattacgagcttcatgcacagtgaaatcatgaaaaatttatttgctttgtgagcggataacaattataatatgtggaattgtgagcgctcacaattccacaacg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z