BBa_K602003
1
BBa_K602003
<i>Deinococcus radiodurans</i> RecA
2011-10-02T11:00:00Z
2015-05-08T01:12:50Z
Obtained by PCR from genomic DNA.
Component of the DNA double-strand break repair mechanism in <i>Deinococcus radiodurans</i>. Binds preferentially to dsDNA even in the presence of ssDNA, unlike <i>E. coli</i> RecA. Essential for radiotolerance of <i>D. radiodurans</i>.
false
false
_774_
0
7851
9
It's complicated
false
We have designed part according to BBF RFC 54, which modifies the prefix and suffix to allow for the use of shorter PCR cloning primers but can be assembled in the usual way (i.e. Standard Assembly, RFC 10).
false
Toshiyuki Otake, Youfeng Lin, Shuhei Yasumoto, Takahiro Saka, Rie Takino, Shaothing Teoh
annotation2151607
1
stop
range2151607
1
1090
1095
annotation2151606
1
start
range2151606
1
1
3
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_K602020
1
BBa_K602020
<i>D. radiodurans</i> PprM+RecA expression device
2011-10-26T11:00:00Z
2015-05-08T01:12:50Z
Standard assembly of the component parts.
<i>D. radiodurans</i> PprM and RecA, each with own LacI promoter and RBS. Constitutively expresses these two proteins and should increase DNA damage repair capability and radioresistance of host <i>E. coli</i>.
false
false
_774_
0
10901
9
It's complicated
true
N/A
false
Toshiyuki Otake, Youfeng Lin, Shuhei Yasumoto, Takahiro Saka, Rie Takino, Shaothing Teoh
component2160860
1
BBa_B0034
component2160872
1
BBa_B0034
component2160875
1
BBa_K602003
component2160863
1
BBa_K602002
component2160864
1
BBa_R0010
component2160852
1
BBa_R0010
annotation2160875
1
BBa_K602003
range2160875
1
866
1960
annotation2160863
1
BBa_K602002
range2160863
1
227
631
annotation2160852
1
BBa_R0010
range2160852
1
1
200
annotation2160860
1
BBa_B0034
range2160860
1
209
220
annotation2160864
1
BBa_R0010
range2160864
1
640
839
annotation2160872
1
BBa_B0034
range2160872
1
848
859
BBa_K602002
1
BBa_K602002
<i>Deinococcus radiodurans</i> PprM
2011-10-02T11:00:00Z
2015-05-08T01:12:50Z
Obtained by PCR from genomic DNA.
Regulatory protein acting downstream of PprI in the DNA damage response of <i>Deinococcus radiodurans</i>. Homolog of cold shock protein (Csp).
false
false
_774_
0
7851
9
In stock
false
We have designed part according to BBF RFC 54, which modifies the prefix and suffix to allow for the use of shorter PCR cloning primers but can be assembled in the usual way (i.e. Standard Assembly, RFC 10).
false
Toshiyuki Otake, Youfeng Lin, Shuhei Yasumoto, Takahiro Saka, Rie Takino, Shaothing Teoh
annotation2151511
1
start
range2151511
1
1
3
annotation2151512
1
stop
range2151512
1
400
405
BBa_R0010
1
LacI
promoter (lacI regulated)
2003-01-31T12:00:00Z
2015-05-08T01:14:14Z
The Plac insert was PCR'd from the MG1655 strain of E.coli K12.
Released HQ 2013
Inverting regulatory region controlled by LacI (<bb_part>BBa_C0010</bb_part>, <bb_part>BBa_C0011</bb_part>, etc.) <p> The pLac regulatory region is a 243 base-pair sequence with standard BioBrick prefix and suffix sections on its ends. It contains two protein binding sites: CAP, which is generally present in E.coli and is assocciated with cell health and availability of glucose., and LacI, the Lac inhibitor <bb_part>BBa_C0010</bb_part> which binds in an dimerized cooperative manner to inhibit the transcription of the protein that follows. In the presence of lactose or IPTG, an analog of lactose, LacI is unable to correctly bind and inhibit transcription. This allows <bb_part>BBa_R0010</bb_part> to be used as a inverter or as a detector of lactose or IPTG.
false
true
_1_
0
24
7
In stock
false
<P> <P><P> LacI binds to this regulator. This part is incompatible with species containing active LacI coding regions. Lactose and IPTG disable the operation of LacI and this regulator. This part is incompatible with environments containing lactose or lactose analogs.
true
annotation1961227
1
start
range1961227
1
173
173
annotation1961223
1
CAP binding site
range1961223
1
89
126
annotation1961222
1
BBa_R0010
range1961222
1
1
200
annotation1961225
1
-10
range1961225
1
161
166
annotation1961226
1
LacI binding site
range1961226
1
166
200
annotation1961224
1
-35
range1961224
1
137
142
annotation1961221
1
end of LacI coding region (inactive)
range1961221
1
1
88
BBa_K602003_sequence
1
atgagcaaggacgccaccaaagaaatctccgcccccaccgacgccaaggaacgcagcaaggccatcgaaacagccatgagccagatcgaaaaggccttcggcaagggctcgatcatgaaactgggcgccgagagcaaactcgacgtgcaggtcgtcagcaccggcagcctcagccttgacctcgcactgggcgtgggcggcattccgcgtggccgcatcaccgagatctacggccccgagtcgggcggcaagaccaccctggccctcgccatcgtcgcgcaggcccagaaagcgggcggcacctgtgcgtttatcgacgccgagcacgcgctcgacccggtgtacgcccgcgccctgggcgtgaacaccgacgaactgctggtgtcgcagcccgacaacggcgagcaggcgctcgaaatcatggaactgctggtgcgttcgggcgcgattgatgtggtggtcgtggactcggtggctgctctgaccccccgcgccgaaatcgagggcgacatgggcgacagcctgcccggtcttcaggcccgcctgatgtcgcaggcgctgcgcaagctgacggcgattctctccaagaccggcaccgccgccatcttcatcaaccaggttcgcgagaaaatcggcgtgatgtacggcaaccccgaaaccaccaccgggggccgggcgctgaagttctacgccagcgtgcgcctcgacgtgcgtaagatcggccagcccaccaaggtcggcaacgacgcggtcgccaacaccgtcaagatcaagaccgtgaagaacaaggtcgccgcccccttcaaggaagtcgaactcgcgctggtctacggcaagggcttcgaccagctcagcgacctcgtgggcctggccgccgacatggacatcatcaagaaggccggcagcttctactcctacggcgacgagcgcatcggccagggcaaggaaaagaccatcgcctacatcgccgagcgccccgagatggagcaggaaatccgcgaccgcgtgatggccgccatccgcgcgggcaacgcgggcgaagcaccggccctggcccccgcgcctgccgcgcccgaagccgccgaagcgtaataa
BBa_R0010_sequence
1
caatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacaca
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K602020_sequence
1
caatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacacatactagagaaagaggagaaatactagatgtgccgagtttcgattgttggtggcggtggcccctatcttgcctctcgttcaacaccagcagagaacttgaagggacatgccgggaaaagagcaacagcggcatgtggccttttgttggtgagagcaaggagatttgagatggcaactggaagagtgaagtggttcaacgcggaaaaaggcttcggctttatcgagacggaaggcagcgccgatgtattcgcgcactacagcgcgatcaactcctcgggcttccgcaagctcaacgaaggtgacgaagtcgagttcgaaattgaacccggtcagaacggcaaaggcccccaggccaagaacatcgtggtgaccaaggcagcccccgcgcccgcctatggtgaccgcccccgccgcgacgaccgctggtaataatactagagcaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtggaattgtgagcggataacaatttcacacatactagagaaagaggagaaatactagatgagcaaggacgccaccaaagaaatctccgcccccaccgacgccaaggaacgcagcaaggccatcgaaacagccatgagccagatcgaaaaggccttcggcaagggctcgatcatgaaactgggcgccgagagcaaactcgacgtgcaggtcgtcagcaccggcagcctcagccttgacctcgcactgggcgtgggcggcattccgcgtggccgcatcaccgagatctacggccccgagtcgggcggcaagaccaccctggccctcgccatcgtcgcgcaggcccagaaagcgggcggcacctgtgcgtttatcgacgccgagcacgcgctcgacccggtgtacgcccgcgccctgggcgtgaacaccgacgaactgctggtgtcgcagcccgacaacggcgagcaggcgctcgaaatcatggaactgctggtgcgttcgggcgcgattgatgtggtggtcgtggactcggtggctgctctgaccccccgcgccgaaatcgagggcgacatgggcgacagcctgcccggtcttcaggcccgcctgatgtcgcaggcgctgcgcaagctgacggcgattctctccaagaccggcaccgccgccatcttcatcaaccaggttcgcgagaaaatcggcgtgatgtacggcaaccccgaaaccaccaccgggggccgggcgctgaagttctacgccagcgtgcgcctcgacgtgcgtaagatcggccagcccaccaaggtcggcaacgacgcggtcgccaacaccgtcaagatcaagaccgtgaagaacaaggtcgccgcccccttcaaggaagtcgaactcgcgctggtctacggcaagggcttcgaccagctcagcgacctcgtgggcctggccgccgacatggacatcatcaagaaggccggcagcttctactcctacggcgacgagcgcatcggccagggcaaggaaaagaccatcgcctacatcgccgagcgccccgagatggagcaggaaatccgcgaccgcgtgatggccgccatccgcgcgggcaacgcgggcgaagcaccggccctggcccccgcgcctgccgcgcccgaagccgccgaagcgtaataa
BBa_K602002_sequence
1
atgtgccgagtttcgattgttggtggcggtggcccctatcttgcctctcgttcaacaccagcagagaacttgaagggacatgccgggaaaagagcaacagcggcatgtggccttttgttggtgagagcaaggagatttgagatggcaactggaagagtgaagtggttcaacgcggaaaaaggcttcggctttatcgagacggaaggcagcgccgatgtattcgcgcactacagcgcgatcaactcctcgggcttccgcaagctcaacgaaggtgacgaagtcgagttcgaaattgaacccggtcagaacggcaaaggcccccaggccaagaacatcgtggtgaccaaggcagcccccgcgcccgcctatggtgaccgcccccgccgcgacgaccgctggtaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z