BBa_K618111
1
BBa_K618111
pBAD ompA-Gli1
2011-09-26T11:00:00Z
2015-05-08T01:12:54Z
parts come from iGEM distribution
This is a fusion between ompA and the DNA binding protein Gli-1. It should be present on the outer surface of cells and bind the Gli-! recognition sequence there. This will also allows cells to be anchored to glass slide with the DNA attached.
false
false
_790_
0
8977
9
It's complicated
false
Silver prefix on Gli-1 allowed us to fuse it to ompA in frame.
false
Chris Bate, Ben Park, Marc Ammerlaan
component2144562
1
BBa_K103006
component2144563
1
BBa_K165007
component2144556
1
BBa_K259007
annotation2144556
1
BBa_K259007
range2144556
1
1
360
annotation2144562
1
BBa_K103006
range2144562
1
369
832
annotation2144563
1
BBa_K165007
range2144563
1
841
1365
BBa_J61100
1
BBa_J61100
Ribosome Binding Site Family Member
2007-01-28T12:00:00Z
2015-08-31T02:03:00Z
N/A
{{JCA_Arkin_RBSFamily}}
false
true
_95_
0
483
95
In stock
false
N/A
true
John Anderson
BBa_K103006
1
OmpA
OmpA outer membrane protein A fused to linker; displays proteins on cell surface
2008-09-13T11:00:00Z
2015-05-08T01:08:46Z
One of our basic bricks used to create fusions attached to outer membrane
false
true
_180_
0
2582
9
In stock
true
true
Michael Lower
annotation1990002
1
SacI
range1990002
1
459
464
annotation1993480
1
ATG
range1993480
1
4
6
annotation1990001
1
linker
range1990001
1
439
464
annotation1989999
1
NdeI
range1989999
1
1
7
annotation1990000
1
OmpA
range1990000
1
4
438
BBa_K165007
1
BBa_K165007
Gli-1 DNA-binding domain
2008-10-25T11:00:00Z
2015-05-08T01:10:55Z
-
-
false
false
_267_
0
2512
58
It's complicated
true
-
false
John Szymanski
BBa_R0081
1
AraC O2
Inhibitor (AraC loop attachment with O2 site)
2004-01-29T12:00:00Z
2015-05-08T01:14:15Z
Released HQ 2013
this piece of DNA contains a "dead" part of coding region for AraC, and a functional Operator2 site. when attached to the rest of the promoter region, this part allows for the binding and loop formation that would result in repression of the araC promoter
false
false
_1_
0
24
7
In stock
false
1) changed ATG start codon to TAG stop
2) 6 random deletions upstream of putative araC binding sites to preserve spacing for loop back (BB ends will add 6 base pairs); spacing crucial in matching up O2 and I2 binding sites (turns of DNA helix)
3) designed to attach to R0080 to enable all (positive and negative) regulatory functions, and to form "loop back"
true
Sara Neves (Fighting Darwins)
annotation331787
1
stem_loop
range331787
1
57
72
annotation331785
1
defunct araC
range331785
1
1
78
annotation331786
1
stem_loop
range331786
1
22
37
BBa_K259007
1
BBa_K259007
AraC Promoter fused with RBS
2009-09-08T11:00:00Z
2015-05-08T01:11:42Z
The AraC promoter can be found naturally at 1.52min of the E.coli genome ([http://ecogene.org/geneinfo.php?eg_id=EG10054 EcoGene number EG10054].
The RBS was taken from the designed sequences of RBS by the Anderson family. For more information visit the original part page [http://partsregistry.org/Part:BBa_J61100 here].
This part has the arabinose regulated promoter (AraC/pBAD) upstream of a ribosome binding site. This is ideal for inserting a protein to be expressed downstream of this part as it's expression can be regulated by the presence of the concentration of arabinose in the growing environment/media of the cells.
==What this part actually does==
This composite part includes the AraC/pBAD promoter and a strong ribosome binding site designed from the Anderson family of RBS.
The AraC/pBAD promoter can be used with prokaryotic chassis to regulate expresion of proteins.
When the AraC/pBAD promoter is placed upstream of your canditate translational unit (protein to be expressed) it allows control of the trancription of the said protein. This is done via controlling the concentration of arabinose sugar in the environment/solution of bacterial growth.
Controlling the transcription will not ensure translation. The ribosome binding site is ideally placed a small distance away from the promoter site to ensure that the ribosome will bind and start translating the protein coding sequence found downstream.
false
false
_357_
0
5318
9
It's complicated
false
The part was designed with RFC10 assembly from supplied biobricks of the iGEM2009 distribution.
false
Petros Mina
component2020547
1
BBa_J61100
component2020546
1
BBa_R0080
component2020539
1
BBa_R0081
annotation2020539
1
BBa_R0081
range2020539
1
1
183
annotation2020547
1
BBa_J61100
range2020547
1
349
360
annotation2020546
1
BBa_R0080
range2020546
1
192
340
BBa_R0080
1
AraC
Promoter (AraC regulated)
2004-01-27T12:00:00Z
2015-05-08T01:14:15Z
GenBank: J01641 (www.ncbi.nlm.nih.gov)
Released HQ 2013
AraC operator, truncated to include araO1, araI1, araI2, c-amp1, and c-amp2 sites. This operator should *activate* transcription in the presence of AraC; b/c the operator lacks the araO2 site, there should not be araC-mediated repression.
false
false
_1_
0
24
7
In stock
false
true
Sara Neves (Fighting Darwins)
annotation301462
1
ara1 and ara2
range301462
1
73
101
annotation301458
1
c-amp1
range301458
1
43
72
annotation301456
1
c-amp2
range301456
1
4
29
annotation301457
1
araO1
range301457
1
6
44
annotation308601
1
-35
range308601
1
113
118
annotation308602
1
-10
range308602
1
136
141
BBa_K103006_sequence
1
catatgaaagctactaaactggtactgggcgcggtaatcctgggttctactctgctggcaggttgctccagcaacgctaaaatcgatcagggaattaacccgtatgttggctttgaaatgggttacgactggttaggtcgtatgccgtacaaaggcagcgttgaaaacggtgcatacaaagctcagggcgttcaactgaccgctaaactgggttacccaatcactgacgacctggacatctacactcgtctgggtggcatggtatggcgtgcagacactaaatccaacgtttatggtaaaaaccacgacaccggcgtttctccggtcttcgctggcggtgttgagtacgcgatcactcctgaaatcgctacccgtctggaataccagtggaccaacaacatcggtgacgcacacaccatcggcactcgtccggacaacggcggaggttctggaggagggagctc
BBa_K259007_sequence
1
caggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgctacagacattgccgtcactggtctttactggctcttctcgctaaccaaaccggtaaccgcttattaaagcattctgtaacaaagcgggaccaaagccatgacaaaactactagaggcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccattactagagaaagaggggaca
BBa_J61100_sequence
1
aaagaggggaca
BBa_K618111_sequence
1
caggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgctacagacattgccgtcactggtctttactggctcttctcgctaaccaaaccggtaaccgcttattaaagcattctgtaacaaagcgggaccaaagccatgacaaaactactagaggcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccattactagagaaagaggggacatactagagcatatgaaagctactaaactggtactgggcgcggtaatcctgggttctactctgctggcaggttgctccagcaacgctaaaatcgatcagggaattaacccgtatgttggctttgaaatgggttacgactggttaggtcgtatgccgtacaaaggcagcgttgaaaacggtgcatacaaagctcagggcgttcaactgaccgctaaactgggttacccaatcactgacgacctggacatctacactcgtctgggtggcatggtatggcgtgcagacactaaatccaacgtttatggtaaaaaccacgacaccggcgtttctccggtcttcgctggcggtgttgagtacgcgatcactcctgaaatcgctacccgtctggaataccagtggaccaacaacatcggtgacgcacacaccatcggcactcgtccggacaacggcggaggttctggaggagggagctctactagagaagcgtgagcctgaatctgtgtatgaaactgactgccgttgggatggctgtagccaggaatttgactcccaagagcagctggtgcaccacatcaacagcgagcacatccacggggagcggaaggagttcgtgtgccactgggggggctgctccagggagctgaggcccttcaaagcccagtacatgctggtggttcacatgcgcagacacactggcgagaagccacacaagtgcacgtttgaagggtgccggaagtcatactcacgcctcgaaaacctgaagacgcacctgcggtcacacacgggtgagaagccatacatgtgtgagcacgagggctgtagtaaagccttcagcaatgccagtgaccgagccaagcaccagaatcggacccattccaatgagaagccgtatgtatgtaagctccctggctgcaccaaacgctatacagatcctagctcgctgcgaaaacatgtcaagacagtgcatggtcctgacgcccatgtgaccaaacggcaccgtggggat
BBa_R0081_sequence
1
caggggatcattttgcgcttcagccatacttttcatactcccgccattcagagaagaaaccaattgtccatattgctacagacattgccgtcactggtctttactggctcttctcgctaaccaaaccggtaaccgcttattaaagcattctgtaacaaagcgggaccaaagccatgacaaaac
BBa_K165007_sequence
1
aagcgtgagcctgaatctgtgtatgaaactgactgccgttgggatggctgtagccaggaatttgactcccaagagcagctggtgcaccacatcaacagcgagcacatccacggggagcggaaggagttcgtgtgccactgggggggctgctccagggagctgaggcccttcaaagcccagtacatgctggtggttcacatgcgcagacacactggcgagaagccacacaagtgcacgtttgaagggtgccggaagtcatactcacgcctcgaaaacctgaagacgcacctgcggtcacacacgggtgagaagccatacatgtgtgagcacgagggctgtagtaaagccttcagcaatgccagtgaccgagccaagcaccagaatcggacccattccaatgagaagccgtatgtatgtaagctccctggctgcaccaaacgctatacagatcctagctcgctgcgaaaacatgtcaagacagtgcatggtcctgacgcccatgtgaccaaacggcaccgtggggat
BBa_R0080_sequence
1
gcgtaacaaaagtgtctataatcacggcagaaaagtccacattgattatttgcacggcgtcacactttgctatgccatagcatttttatccataagattagcggatcctacctgacgctttttatcgcaactctctactgtttctccat
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z