BBa_K619889
1
BBa_K619889
prfA-UTR, RNA thermosensor from Listeria monocytogenes
2011-09-25T11:00:00Z
2015-05-08T01:12:54Z
The source of the DNA sequence is Listeria monocytogenes prfA-UTR, however we constructed this part by simply ordering DNA oligos and annealing them.
This part contains prfA-UTR, an RNA thermosensor from Listeria monocytogenes originally characterized by Johansson et al. Cell 110:551561. The secondary structure of this RNA forms at hairpin at 30'C which masks the ribosomal binding site and initiating ATG. At 37'C this hairpin melts allowing ribosomes to bind and translation to proceed. Be sure that your gene fusion is in frame since the initiating ATG for translation is encoded in this DNA (see diagram from paper). Sequence just before initiating ATG is GAGACATG where the ATG in this sequence is the initiating ATG.
false
true
_791_
0
8978
9
It's complicated
false
false
Julianne Grose
annotation2146685
1
rbs
range2146685
1
113
118
annotation2146686
1
start
range2146686
1
125
127
BBa_K619889_sequence
1
tgcagtttagcgtgcggctgcagtttagcgtgactttctttcaacagctaacaattgttgttactgcctaatgtttttagggtattttaaaaaagggcgataaaaaacgattggaggatgagacatgaacgctcaaaagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z