BBa_K619890
1
BBa_K619890
mutated prfA thermosensor from listeria
2011-09-26T11:00:00Z
2015-05-08T01:12:54Z
This is the prfA-UTR from Listeria monocytogenes.
This is the prfA-UTR from Listeria monocytogenes which has been randomly mutated to produce a thermosensor this a more discrete dynamic range. In contrast to the our wild type thermosensor (part BBa_K619889) which activates translation from a 30 to 37 degree shift, this thermosensor activates transcription from a 35 to 37 degree shift. This mutation was isolated by randomly mutagenizing part BBa_K619889 and monitoring a lacZ output.
false
false
_791_
0
8978
9
It's complicated
false
see BBa_K619889, the Shine-Delagarno was mutated from GGGGGA to GGAGGA in order to optimize expression in E. coli, otherwise the thermosensor is the original sequence of prfA-UTR from Listeria monocytogenes.
false
Julianne Grose
annotation2144637
1
start
range2144637
1
125
127
annotation2144636
1
rbs
range2144636
1
113
118
BBa_K619890_sequence
1
tgcagtttagcgtgcggctgcagtttagcgtgactttctttcaacggctaacaatcgttgttactgcctaaagtttttagggtattttaaaaaagggcgataaaaaacgattggaggatgagacatgaacgctcaaaagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z