BBa_K619895
1
BBa_K619895
mutated prfA-UTR thermosensor from Listeria monocytogenes
2011-09-26T11:00:00Z
2015-05-08T01:12:54Z
prfA-UTR from Listeria monocytogenes
This is the prfA-UTR thermosensor mutated to produce a thermosensor with increassed expression at both 30 and 37 degrees. On can still detect an increase in expression when switching from 30 to 37 degrees. Characterization of its dynamic range is underway. The part was made by TAQ-mediated random mutagenesis of our "wild-type" thermosensor (BBa-19889) and subsequent screening using a lacZ reporter. There are other thermosensors entered into the IGEM database with different dynamic ranges obtained from this screen. To use this thermosensor, be sure to clone in frame with the indicated initiating ATG.
false
false
_791_
0
8978
9
It's complicated
false
Our "wild-type" thermosensor (BBa-19889) Shine-Delagarno has been optimized for expression in E. coli. Otherwise, the "wild-type" sequence is identical to the thermosensor sequence from Listeria monocytogenes.
false
Julianne Grose
annotation2144645
1
rbs
range2144645
1
113
118
annotation2144646
1
start
range2144646
1
125
127
BBa_K619895_sequence
1
tgcagtttagcgtgcggctgcagtttagcgtgactttctttcaacagctaacaattgttgttactgcctaatgtttttagggtattttaaaaaagggcgataaaaaacgattggaggatgagacatgaacgctcaaaagc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z