BBa_K364202
1
BBa_K364202
hBAX
2010-08-09T11:00:00Z
2015-05-08T01:12:14Z
Human BAX (of the Bcl-2 gene family)
Coding sequence of Bax (Bcl-2-associated X) protein which is a pro-apoptotic meber of the Bcl-2 protein family. It contains four BH (Bcl-2 homology) domains, can form homo- and heterodimers and plays essential role in the formation of MOMP (Mitochondrial outer membrane permeabilization) leading to apoptosis which is the most frequent type of PCD (Programmed cell death).
false
false
_486_
0
6885
9
It's complicated
true
Compatible with RFC-10 and RFC-25.
false
Endre K??roly Krist??f
annotation2077557
1
BH3 domain
range2077557
1
177
219
annotation2077560
1
Transmembrane domain
range2077560
1
516
573
annotation2077558
1
BH1 domain
range2077558
1
294
354
annotation2077559
1
BH2 domain
range2077559
1
450
495
BBa_K364302
1
BBa_K364302
PolyA
2010-08-10T11:00:00Z
2015-05-08T01:12:14Z
Arteficial
The PolyA tail of mRNA has multiple adenilates which is important for the nuclear export, translation and stability of mRNA in eukaryotes.
false
false
_486_
0
6885
9
It's complicated
true
Compatible with RFC-10 and RFC-25.
false
Endre K??roly Krist??f
BBa_K626000
1
BBa_K626000
TRE-Bax-PolyA in PSB1A3 (expression vector)
2011-08-31T11:00:00Z
2015-05-08T01:12:56Z
Artificial and human BAX.
Expression vector from standard BioBrick parts, expressing human pro-apoptotic protein BAX.
false
false
_486_798_
0
6885
9
It's complicated
true
Compatible with RFC-10 and RFC-25.
false
Endre K??roly Krist??f
component2125758
1
BBa_K364304
component2125763
1
BBa_K364202
component2125764
1
BBa_K364302
annotation2125764
1
BBa_K364302
range2125764
1
911
1101
annotation2125758
1
BBa_K364304
range2125758
1
1
321
annotation2125763
1
BBa_K364202
range2125763
1
330
902
BBa_K364304
1
BBa_K364304
TRE-CMV
2010-08-12T11:00:00Z
2015-05-08T01:12:14Z
Arteficial
The Tetracycline Response Element (TRE) is recognized and bound by the Tetracycline repressor (TetR) protein. The TRE consists of 7 repeats separated by spacer sequences and placed upstream of CMV minimal promoter that has basal expession in the abscence of bound TetR. Tetracycline derivatives (e.g. doxycycline) bind TetR and render it incapable of binding to TRE, thereby forcing the expression of target genes.
false
false
_486_
0
6885
9
It's complicated
true
Compatible with RFC-25 and RFC-10.
false
Endre K??roly Krist??f
annotation2077766
1
4th tetO
range2077766
1
116
134
annotation2077763
1
1st tetO
range2077763
1
9
27
annotation2077767
1
5th tetO
range2077767
1
152
170
annotation2077768
1
6th tetO
range2077768
1
187
205
annotation2077769
1
7th tetO
range2077769
1
223
241
annotation2077762
1
minimal P-CMV
range2077762
1
255
315
annotation2077764
1
2nd tetO
range2077764
1
45
63
annotation2077761
1
TRE
range2077761
1
1
249
annotation2077765
1
3rd tetO
range2077765
1
80
98
BBa_K364304_sequence
1
tcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttatccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgaggtaggcgtgtacggtgggaggcctatataagcagagctcgtttagtgaaccgtcagatcgcctgga
BBa_K364302_sequence
1
ggatcataatcagccataccacatttgtagaggttttacttgctttaaaaaacctcccacacctccccctgaacctgaaacataaaatgaatgcaattgttgttgttaacttgtttattgcagcttataatggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcct
BBa_K364202_sequence
1
gacggcagcggcgagcagccccgcggcggcggccccaccagcagcgagcagatcatgaagaccggcgccctgctgctccagggcttcatccaggaccgcgcaggccgcatgggcggcgaggcccccgagctggccctggaccccgtgccccaggacgccagcaccaagaagctgagcgagtgcctgaagcgcatcggcgacgagctggacagcaacatggagctccagcgcatgatcgccgccgtggacaccgacagcccccgcgaggtgttcttccgcgtggccgccgacatgttcagcgacggcaacttcaactggggccgcgtggtggccctgttctacttcgccagcaagctggtgctgaaggccctgtgcaccaaggtgcccgagctgatccgcaccatcatgggctggaccctggacttcctgcgcgagcgcctgctgggctggatccaggaccagggcggctgggacggcctgctgagctacttcggcacccccacctggcagaccgtgaccatcttcgtggcaggcgtgctgaccgccagcctgaccatctggaagaagatgggc
BBa_K626000_sequence
1
tcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgagtttatccctatcagtgatagagaacgtatgtcgagtttactccctatcagtgatagagaacgtatgtcgaggtaggcgtgtacggtgggaggcctatataagcagagctcgtttagtgaaccgtcagatcgcctggatactagaggacggcagcggcgagcagccccgcggcggcggccccaccagcagcgagcagatcatgaagaccggcgccctgctgctccagggcttcatccaggaccgcgcaggccgcatgggcggcgaggcccccgagctggccctggaccccgtgccccaggacgccagcaccaagaagctgagcgagtgcctgaagcgcatcggcgacgagctggacagcaacatggagctccagcgcatgatcgccgccgtggacaccgacagcccccgcgaggtgttcttccgcgtggccgccgacatgttcagcgacggcaacttcaactggggccgcgtggtggccctgttctacttcgccagcaagctggtgctgaaggccctgtgcaccaaggtgcccgagctgatccgcaccatcatgggctggaccctggacttcctgcgcgagcgcctgctgggctggatccaggaccagggcggctgggacggcctgctgagctacttcggcacccccacctggcagaccgtgaccatcttcgtggcaggcgtgctgaccgccagcctgaccatctggaagaagatgggctactagagggatcataatcagccataccacatttgtagaggttttacttgctttaaaaaacctcccacacctccccctgaacctgaaacataaaatgaatgcaattgttgttgttaacttgtttattgcagcttataatggttacaaataaagcaatagcatcacaaatttcacaaataaagcatttttttcactgcct
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z