BBa_K644000
1
BBa_K644000
Extracellular Domain of E-Cadherin (Mouse)
2011-08-30T11:00:00Z
2015-05-08T01:12:58Z
Mus musculus (mouse)
Cadherin is an adhesive transmembrane and calcium dependent protein that is expressed in many mammalian tissue cells and plays a role in keeping tissues together. It has a domain that anchors the protein to the cytoskeleton of the mammalian cells, an intercellular domain, and five extracellular domain repeats. With the presence of calcium ions, the extracellalur domains become rigid and are able to form homodimers with the same type of cadherin or form heterodimers with different types of cadherin, hence creating cell to cell adhesion.
false
false
_820_
0
10307
9
It's complicated
false
Our E-cadherin only contains the extracellular gene sequence because we only needed the extracellular region for our project. Since the E-cadherin gene sequence has an EcoRI restriction endonuclease site, we had to use the Gibson Assembly to clone our E-cadherin gene into the BioBrick plasmid (pSB1C3).
false
Kingsley Lim
BBa_K644000_sequence
1
ctcagaagacagaaacgagactgggtcatccctcccatcagctgccccgaaaatgaaaagggtgagttcccaaagaacctggttcagatcaaatccaacagggacaaagaaacaaaggttttctacagcatcaccggccaaggagctgacaaaccccccgttggcgttttcatcattgagagggagacaggctggctgaaagtgacacagcctctggatagagaagccattgccaagtacatcctctattctcatgccgtgtcatcaaatggggaagcggtggaggatcccatggagatagtgatcacagtgacagatcagaatgacaacaggccagagtttacccaggaggtgtttgagggatccgttgcagaaggcgctgttccaggaacctccgtgatgaaggtctcagccaccgatgcagacgatgacgtcaacacctacaacgctgccatcgcctacaccatcgtcagccaggatcctgagctgcctcacaaaaacatgttcactgtcaatagggacaccggggtcatcagtgtgctcacctctgggctggaccgagagagttaccctacatacactctggtggttcaggctgctgaccttcaaggcgaaggcttgagcacaacagccaaggctgtgatcactgtcaaggatattaatgacaacgctcctgtcttcaacccgagcacgtatcagggtcaagtgcctgagaatgaggtcaatgcccggatcgccacactcaaagtgaccgatgatgatgcccccaacactccggcgtggaaagctgtgtacaccgtagtcaacgatcctgaccagcagttcgttgtcgtcacagaccccacgaccaatgatggcattttgaaaacagccaagggcttggattttgaggccaagcagcaatacatccttcatgtgagagtggagaacgaggaaccctttgaggggtctcttgtcccttccacagccactgtcactgtggacgtggtagacgtgaatgaagcccccatctttatgcctgcggagaggagagtcgaagtgcccgaagactttggtgtgggtcaggaaatcacatcttataccgctcgagagccggacacgttcatggatcagaagatcacgtatcggatttggagggacactgccaactggctggagattaacccagagactggtgccattttcacgcgcgctgagatggacagagaagacgctgagcatgtgaagaacagcacatatgtagctctcatcatcgccacagatgatggttcacccattgccactggcacgggcactcttctcctggtcctgttagacgtcaatgacaacgctcccatcccagaacctcgaaacatgcagttctgccagaggaacccacagcctcatatcatcaccatcttggatccagaccttccccccaacacgtccccctttactgctgagctaacccatggggccagcgtcaactggaccattgagtataatgacgcagctcaagaatctctcattttgcaaccaagaaaggacttagagattggcgaatacaaaatccatctcaagctcgcggataaccagaacaaagaccaggtgaccacgttggacgtccatgtgtgtgactgtgaagggacggtcaacaactgcatgaaggcgggaatcgtggcagcaggattgcaagttcctgccatcctcggaatccttggagggatcctc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z