BBa_K748000 1 BBa_K748000 AgrA protein coding sequence. AgrA is the main component of S.aureus agr quorum sensing system. 2012-09-14T11:00:00Z 2015-05-08T01:13:12Z Staphylococcus aureus genomic sequence Staphylococcus aureus AgrA, the transcriptional component of a quorum sensing system and global regulator of virulence that up-regulates secreted virulence factors and down-regulates cell wall-associated proteins, can bind in both the P2 and P3 promoter regions of the agr locus. The composite of AgrC and AIP then leads to phosphorylation of AgrA. AgrA in its phosphorylated sate activates transcription from both P2 and P3, leading to the production of GFP and 3OC6HSL. Thus we can detect the presence of S.aureus expediently by observing the expression of GFP. false false _999_ 0 8564 9 It's complicated false As a AIP sensor system, agrA should work with agrC. false Lei Qiao BBa_K748000_sequence 1 atggaaattgcattagcaacagataatccatatgaagttttagaacaagcaaaaaatatgaatgatattggttgttattttttagatattcaattatcaacagatattaatggtattaaattaggttcagaaattcgtaaacatgatccagttggtaatattatttttgttacatcacattcagaattaacatatttaacatttgtttataaagttgcagcaatggattttatttttaaagatgatccagcagaattacgtacacgtattattgattgtttagaaacagcacatacacgtttacaattattatcaaaagataattcagttgaaacaattgaattaaaacgtggttcaaattcagtttatgttcaatatgatgatattatgttttttgaatcatcaacaaaatcacatcgtttaattgcacatttagataatcgtcaaattgaattttatggtaatttaaaagaattatcacaattagatgatcgtttttttcgttgtcataattcatttgttgttaatcgtcataatattgaatcaattgattcaaaagaacgtattgtttattttaaaaataaagaacattgttatgcatcagttcgtaatgttaaaaaaatttaataa igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z