BBa_K817015
1
BBa_K817015
srnBC toxin-antitoxin cassette
2012-09-17T11:00:00Z
2015-05-08T01:13:28Z
F plasmid
It is type I toxin-antitoxin which belongs to hok/sok homologues, it expresses stable toxin encoded RNA and short lived antitoxin RNA that can neutralize toxin RNA by RNA interaction. It acts as post segregation killing system, which kills bacteria when it loss the DNA(genomic islands, plasmids, mobile gene elements) that contains it. Therefore we use it to reduce plasmid loss rate and make applications without antibiotics selection pressure more feasible.
false
false
_1075_
0
13960
9
In stock
false
This part only functions when there is not the same srnBC present in the same cell(those F' E.coli like JM109 contain srnBC), or it will be neutralize and functionless .
false
Shan Chi Hsieh
annotation2187455
1
srnB'
range2187455
1
278
427
annotation2187454
1
srnB
range2187454
1
221
427
annotation2187453
1
srnC
range2187453
1
173
234
BBa_K817015_sequence
1
gaacaataatttacggtttcgcgctatagctggctcaagttaggttggaccctgaatctccagacaaccaatatctgatcgcgccagtggtggcagttattaagcaacagggaatgtggtattatcgcggcgggtgtctgagcctttctggttcaggcaagacgcaggtaccagaaatgcgaagaccccacttgttaatccattaactcgtgaggtctgcatgaagtaccttaacactactgattgtagcctcttccttgcagagaggtcaaagtttatgacgaaatatgcccttatcgggttgctcgccgtgtgcgctacggtgttgtgtttttcactgatattcagggaacggttatgtgagctgaatattcacaggggaaatacagtggtgcaggtaactctggcctacgaagcacggaagtaagctgccgggcggggacggaagtccccgctttccggaagtgtgaggtatttcaggggcagacacccgacatgccagaaacagccggtcccgcccggggccggcacccaggttcaggcatttcctgcttttcagtcatttcattatcaaaatcacattaaacggtcgtaatcagac
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z