BBa_K836004
1
gpS
Lysis inhibitor from Enterobacteria phage lambda (codon usage optimized for R. opacus)
2012-09-19T11:00:00Z
2015-05-08T01:13:32Z
The amino sequence was obtained from Uniprot (http://www.uniprot.org/uniprot/P03705#section_seq lysis inhibitor isoform). The codon optimization for R. opacus (avoiding standard restriction sites EcoRI, PstI, XbaI and SpeI) was made using the free software GeneDesigner from DNA 2.0.
This protein is the one in charge to avoid the formation of pores in the inner membrane of the bacterial cell. It has been optimized for expression in R. opacus. A weak RBS for Gram positive bacteria was used (http://partsregistry.org/Part:BBa_K090506:Design)in order to obtain low concentration of the protein.
false
false
_1095_
0
11819
9
Not in stock
false
We wanted a low concentration of this protein since medium to large concentrations could affect or completely inhibit the lysis device. Basal but constitutive expression of this protein is needed to avoid the formation of pores in the design lysis device.
false
Ricardo Alvarado
annotation2187517
1
Lambda antiholin
range2187517
1
18
338
annotation2187515
1
BBa_K090506
range2187515
1
1
11
annotation2187516
1
Scar
range2187516
1
12
17
BBa_K836004_sequence
1
agaggtggtgttactagatgaaaatgcctgagaaacatgacctgctcgccgcaatcctggcagccaaggaacagggcattggcgccatcctggccttcgcgatggcgtatctccgcggtcggtacaacggcggagccttcaccaagaccgtcatcgacgcaaccatgtgcgcgatcatcgcatggttcatcagagatctcctggacttcgccggactgtcgtccaatctcgcctacatcacaagtgtgttcatcgggtacatcggcacggactccatcggctcgctgatcaagcggttcgccgccaagaaggcgggggttgaagacggtcgcaaccaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z