BBa_K861120
1
BBa_K861120
BcsZ, endo-1,4-D-glucanase
2012-09-06T11:00:00Z
2015-06-17T01:21:47Z
Escherichia coli str. K-12 substr. MG1655
BcsA, BcsB, BcsZ and BcsC are involved in biosynthesis of cellulose, a characteristic of the rdar morphotype.The bcsZ gene encodes an endo-1,4-D-glucanase which belongs to glycosyl hydrolase family 8 . First 21 aa are predicted to be a type I signal peptide.The activity of BcsZ is required for optimal synthesis and membrane translocation of cellulose.
false
false
_1121_
0
4206
12357
9
It's complicated
false
None
false
Xian Xia
BBa_K861171
1
Pcar
Pcar, synthetic promoter repressed by CRP
2012-09-06T11:00:00Z
2015-05-08T01:13:36Z
Escherichia coli str. K-12 substr. MG1655
This is a promoter designed for the Eschaerichia coli . It includes the CRP-binding site and the RNA polymerase-binding site which have a overlap of several base pairs.So because of the steric hindrance between CRP and RNA polymerase,gene downstream of the promoter will be repressed at high concentration of CRP.In the cells ,low glucose concentration results in increased activity by adenylate cyclase. cAMP binds to the cAMP receptor protein, which, in its bound form, is able to bind tightly to the specific DNA site in the promoter and repress the gene downstream.On the contrary,high glucose concentration will result in the expression of the promoter.
false
false
_1121_
0
12357
9
In stock
true
None
false
Kuanwei Sheng
annotation2183482
1
Consensus CRP binding site
range2183482
1
15
36
BBa_B0024
1
BBa_B0024
double terminator (B0012-B0011), reversed
2003-12-02T12:00:00Z
2015-08-31T04:07:20Z
-- No description --
false
false
_1_
0
24
7
In stock
false
true
Caitlin Conboy
BBa_K861122
1
BBa_K861122
BcsZ generator repressed by CRP (directly)
2012-09-06T11:00:00Z
2015-05-08T01:13:35Z
Escherichia coli str. K-12 substr. MG1655
BcsZ is controlled by promoter PII which can be repressed by CRP-cAMP complex.So the expression of BcsZ will be repressed at high concentration of CRP-cAMP complex.On the contrary,BcsZ can be expressed at low concentration of CRP-cAMP complex.
false
false
_1121_
0
12357
9
It's complicated
false
None
false
Xian Xia
component2181993
1
BBa_K861121
component2181987
1
BBa_K861171
annotation2181993
1
BBa_K861121
range2181993
1
45
1275
annotation2181987
1
BBa_K861171
range2181987
1
1
36
BBa_B0030
1
BBa_B0030
RBS.1 (strong) -- modified from R. Weiss
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
Strong RBS based on Ron Weiss thesis. Strength is considered relative to <bb_part>BBa_B0031</bb_part>, <bb_part>BBa_B0032</bb_part>, <bb_part>BBa_B0033</bb_part>.
false
true
_44_46_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix ("orig" in figure 4-14 of Ron Weiss thesis). <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation1702
1
RBS
range1702
1
8
12
annotation1701
1
RBS-1\Strong
range1701
1
1
15
annotation7025
1
BBa_B0030
range7025
1
1
15
BBa_K861121
1
BBa_K861121
BcsZ with RBS and terminator
2012-09-06T11:00:00Z
2015-05-08T01:13:35Z
Escherichia coli str. K-12 substr. MG1655
BcsA, BcsB, BcsZ and BcsC are involved in biosynthesis of cellulose, a characteristic of the rdar morphotype.The bcsZ gene encodes an endo-1,4-D-glucanase which belongs to glycosyl hydrolase family 8 . First 21 aa are predicted to be a type I signal peptide.The activity of BcsZ is required for optimal synthesis and membrane translocation of cellulose.This device contains BcsZ with a RBS and a terminator.
false
false
_1121_
0
12357
9
It's complicated
false
None
false
Xian Xia
component2181949
1
BBa_B0030
component2181951
1
BBa_K861120
component2181952
1
BBa_B0024
annotation2181949
1
BBa_B0030
range2181949
1
1
15
annotation2181951
1
BBa_K861120
range2181951
1
22
1128
annotation2181952
1
BBa_B0024
range2181952
1
1137
1231
BBa_B0024_sequence
1
aaataataaaaaagccggattaataatctggctttttatattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagtgtga
BBa_K861121_sequence
1
attaaagaggagaaatactagatgaatgtgttgcgtagtggaatcgtgacgatgctgctgctggctgcctttagtgttcaggcagcctgtacctggcctgcctgggagcagtttaaaaaggattacatcagtcaggaagggcgcgtcatcgaccccagcgacgcgcgcaaaatcaccacctccgaagggcaaagttacggcatgttctctgccctggcggctaacgaccgtgcagctttcgataatattctcgactggacgcagaacaatctcgctcagggttctttaaaagaacgtttgcccgcctggctgtggggcaagaaagagaacagtaagtgggaagtgctggacagcaattcggcctccgatggtgatgtctggatggcctggtcgttgctggaggcggggcgtttgtggaaagagcagcgttataccgacatcggcagcgcgttgctaaaacgtatcgcgcgggaggaagtggtgacggtgcctgggctgggttccatgttgttaccgggcaaagtgggttttgctgaggataacagctggcgttttaaccccagctacctgccgccgacgctggcgcagtatttcacccgctttggcgcgccgtggaccacgctgcgcgaaaccaatcaacgtttattgctggaaaccgccccgaaaggtttttcgccagactgggtgcgctatgagaaagacaaaggctggcagctaaaagccgaaaaaacattgatcagcagctacgacgctatccgcgtttacatgtgggtaggcatgatgcctgacagcgatccgcaaaaagcgcggatgctcaaccggtttaaaccgatggcgacattcactgagaaaaacggttatccgccggaaaaagtggatgtggctacggggaaagcgcagggtaaaggaccagtcggtttttctgccgccatgctgccctttttacaaaaccgcgatgcgcaggccgttcagcgccagcgcgtggccgataactttcccggcagcgatgcctattacaactatgtgctgaccctgtttggacaaggctgggatcaacaccgtttccgcttctcgacaaaaggtgagttattacctgactggggccaggaatgcgcaaattcacactaatactagagaaataataaaaaagccggattaataatctggctttttatattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagtgtga
BBa_K861171_sequence
1
ttgacagctagctcaaatgtgatttaaatcacattt
BBa_B0030_sequence
1
attaaagaggagaaa
BBa_K861120_sequence
1
atgaatgtgttgcgtagtggaatcgtgacgatgctgctgctggctgcctttagtgttcaggcagcctgtacctggcctgcctgggagcagtttaaaaaggattacatcagtcaggaagggcgcgtcatcgaccccagcgacgcgcgcaaaatcaccacctccgaagggcaaagttacggcatgttctctgccctggcggctaacgaccgtgcagctttcgataatattctcgactggacgcagaacaatctcgctcagggttctttaaaagaacgtttgcccgcctggctgtggggcaagaaagagaacagtaagtgggaagtgctggacagcaattcggcctccgatggtgatgtctggatggcctggtcgttgctggaggcggggcgtttgtggaaagagcagcgttataccgacatcggcagcgcgttgctaaaacgtatcgcgcgggaggaagtggtgacggtgcctgggctgggttccatgttgttaccgggcaaagtgggttttgctgaggataacagctggcgttttaaccccagctacctgccgccgacgctggcgcagtatttcacccgctttggcgcgccgtggaccacgctgcgcgaaaccaatcaacgtttattgctggaaaccgccccgaaaggtttttcgccagactgggtgcgctatgagaaagacaaaggctggcagctaaaagccgaaaaaacattgatcagcagctacgacgctatccgcgtttacatgtgggtaggcatgatgcctgacagcgatccgcaaaaagcgcggatgctcaaccggtttaaaccgatggcgacattcactgagaaaaacggttatccgccggaaaaagtggatgtggctacggggaaagcgcagggtaaaggaccagtcggtttttctgccgccatgctgccctttttacaaaaccgcgatgcgcaggccgttcagcgccagcgcgtggccgataactttcccggcagcgatgcctattacaactatgtgctgaccctgtttggacaaggctgggatcaacaccgtttccgcttctcgacaaaaggtgagttattacctgactggggccaggaatgcgcaaattcacactaa
BBa_K861122_sequence
1
ttgacagctagctcaaatgtgatttaaatcacattttactagagattaaagaggagaaatactagatgaatgtgttgcgtagtggaatcgtgacgatgctgctgctggctgcctttagtgttcaggcagcctgtacctggcctgcctgggagcagtttaaaaaggattacatcagtcaggaagggcgcgtcatcgaccccagcgacgcgcgcaaaatcaccacctccgaagggcaaagttacggcatgttctctgccctggcggctaacgaccgtgcagctttcgataatattctcgactggacgcagaacaatctcgctcagggttctttaaaagaacgtttgcccgcctggctgtggggcaagaaagagaacagtaagtgggaagtgctggacagcaattcggcctccgatggtgatgtctggatggcctggtcgttgctggaggcggggcgtttgtggaaagagcagcgttataccgacatcggcagcgcgttgctaaaacgtatcgcgcgggaggaagtggtgacggtgcctgggctgggttccatgttgttaccgggcaaagtgggttttgctgaggataacagctggcgttttaaccccagctacctgccgccgacgctggcgcagtatttcacccgctttggcgcgccgtggaccacgctgcgcgaaaccaatcaacgtttattgctggaaaccgccccgaaaggtttttcgccagactgggtgcgctatgagaaagacaaaggctggcagctaaaagccgaaaaaacattgatcagcagctacgacgctatccgcgtttacatgtgggtaggcatgatgcctgacagcgatccgcaaaaagcgcggatgctcaaccggtttaaaccgatggcgacattcactgagaaaaacggttatccgccggaaaaagtggatgtggctacggggaaagcgcagggtaaaggaccagtcggtttttctgccgccatgctgccctttttacaaaaccgcgatgcgcaggccgttcagcgccagcgcgtggccgataactttcccggcagcgatgcctattacaactatgtgctgaccctgtttggacaaggctgggatcaacaccgtttccgcttctcgacaaaaggtgagttattacctgactggggccaggaatgcgcaaattcacactaatactagagaaataataaaaaagccggattaataatctggctttttatattctctctctagtatataaacgcagaaaggcccacccgaaggtgagccagtgtga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z