BBa_K137005
1
pabA
pabA (from pABA synthesis)
2008-06-19T11:00:00Z
2015-05-08T01:10:08Z
L.lactis genome
pabA is a gene involved in para-aminobenzoic acid (pABA) synthesis from chorismate. PABA is necessary for the synthesis of folate.
false
false
_187_
0
2987
9
It's complicated
false
We decided to clone the pABA synthesis genes separately (even though they reside side by side) because L.lactis uses start codons (ttg) that E.coli cannot, and so we need to change the start codon for pabB to atg.
false
Victoria Hsiao
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_B0012
1
BBa_B0012
TE from coliphageT7
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Derived from the TE terminator of T7 bacteriophage between Genes 1.3 and 1.4 <genbank>V01146</genbank>.
Released HQ 2013
Transcription terminator for the <i>E.coli</i> RNA polymerase.
false
false
_1_
0
24
7
In stock
false
<P> <P>Suggested by Sri Kosuri and Drew Endy as a high efficiency terminator. The 5' end cutoff was placed immediately after the TAA stop codon and the 3' end cutoff was placed just prior to the RBS of Gene 1.4 (before AAGGAG).<P> Use anywhere transcription should be stopped when the gene of interest is upstream of this terminator.
false
Reshma Shetty
annotation7020
1
BBa_B0012
range7020
1
1
41
annotation1687
1
stop
range1687
1
34
34
annotation1690
1
polya
range1690
1
28
41
annotation1686
1
T7 TE
range1686
1
8
27
BBa_K909014
1
BBa_K909014
Constitutive expression of pABA
2012-09-21T11:00:00Z
2015-05-08T01:13:45Z
Kinetic characterization of 4-amino 4-deoxychorismate synthase from Escherichia coli. V K Viswanathan,; J M Green and; B P Nichols.
Released HQ 2013
PABA is derived from the aromatic branch point precursor chorismate in two steps. Aminodeoxychorismate (ADC) synthase converts chorismate and glutamine to ADC and glutamate. The conversion of chorismate and glutamine to ADC and glutamate determines the rate and therefore overexpression of ADC synthase leads to overproduction of pABA.
ADC synthase is composed of two subunits, PabA and PabB. Finally ADC lyase removes pyruvate from ADC, aromatizes the ring, and generates PABA.
false
false
_1174_
0
14088
9
In stock
false
xyz
false
Deborah Huber
component2193593
1
BBa_K137006
component2193590
1
BBa_J23100
component2193597
1
BBa_B0010
component2193599
1
BBa_B0012
component2193596
1
BBa_K137005
component2193595
1
BBa_B0034
component2193592
1
BBa_B0034
annotation2193590
1
BBa_J23100
range2193590
1
1
35
annotation2193599
1
BBa_B0012
range2193599
1
2659
2699
annotation2193593
1
BBa_K137006
range2193593
1
62
1951
annotation2193592
1
BBa_B0034
range2193592
1
44
55
annotation2193595
1
BBa_B0034
range2193595
1
1960
1971
annotation2193596
1
BBa_K137005
range2193596
1
1978
2562
annotation2193597
1
BBa_B0010
range2193597
1
2571
2650
BBa_J23100
1
BBa_J23100
constitutive promoter family member
2006-08-03T11:00:00Z
2015-08-31T04:08:40Z
Isolated from library of promoters
Released HQ 2013
Replace later
false
true
_52_
0
483
95
In stock
true
N/A
true
John Anderson
BBa_K137006
1
BBa_K137006
pabB (from pABA synthesis)
2008-06-19T11:00:00Z
2015-05-08T01:10:08Z
L.lactis genome
PabB from L.lactis is a fusion gene of both the usual pabB and pabC in the pABA synthesis pathway from chorismate.
false
false
_187_
0
2987
9
It's complicated
false
The start codon of pabB in L.lactis is TTG, which cannot be used in E.coli. So we designed the primer such that the first T was omitted and the A from the xba1 primer make an ATG start codon.
false
Victoria Hsiao
annotation1971718
1
Changed T to A
range1971718
1
1
1
BBa_B0010
1
BBa_B0010
T1 from E. coli rrnB
2003-11-19T12:00:00Z
2015-08-31T04:07:20Z
Transcriptional terminator consisting of a 64 bp stem-loop.
false
false
_1_
0
24
7
In stock
false
true
Randy Rettberg
annotation7018
1
BBa_B0010
range7018
1
1
80
annotation4184
1
stem_loop
range4184
1
12
55
BBa_J23100_sequence
1
ttgacggctagctcagtcctaggtacagtgctagc
BBa_B0010_sequence
1
ccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctc
BBa_K137006_sequence
1
atgaaggaatttataataaaaaatacggatatttggaaaattttcctaaaatattatcggtcagatgaagaaattgtttttttacatagtagtcaggtgaccgaaaatgagcattatagtattttagctcataaaccttataaaaaggtttcaaaatataagggtcaagtgttttttaatggtgaaaaaaagaagttcaattttttagatgcggtagatttgctgaaggatgagagagttgaacgacctaaaaattggcctttttatccagaattattgggttttgtaagttatgagcaagatccggcttgttttgcagcttatgatgaagttttactttttgaccatagaacaaaactgttacgtgtcgtgcaatttgaacaaactgatggccaatattggctgactgaatcggaagaaattgaagtggattcagagattgagttcgatgttcagaatggcataggggctgtttttattgaccaaacgaggcaagaatatattgcttcaataaaaaaaatacaagattatatgaaggctggcgatatttatgttgccaatttgacgcaacaatttgaaatttggtccgatcaaaaacctattgatgtttttaagaaaacaaggaaacaaattcctgctcctttctcatcatttttacaatatcctgaatggaaaatgacgcaaatttcaagttctgttgaacgctttgtttctattcataatggagcattaatttcaaaacccattaaaggaacaattgccagaggagaaaatgttgtagctgatagattacaaaagaaaatactttccgacagtagtaaagaacggtctgagttactgatggtgacggatttattgcgtaatgatattgcccgaattagtcaacctttttctttgtctgtccctaaatttgcagaaattgaaactttttctcatgttcatcaactggtgacttcaataaaaagtagaattaaagaagatttgactttttcagaatttatgacggctttatttccgggaggttcaatcacaggtacacctaagaagcgggcaatggagattattaaggaagttgaaaaacaacctagaggaatttatacagggatgcagggttggttaagtcgagaaatggatttggatatgaacatcgtgattcggacattagttcatgacggtgagcattatcagcttggtgtaggcggtggaattacgttcgagagcgaagcagaagcagagttttcagagattttactaaaagcaaaaccctttttagatatattaggcctgaaagatgttccaagtattttatttacaacaggccttgttaaaaatggtgaattgttaaatttagagggtcatgtcaatcgcttgaaaaaacaataccatcatgcagatttggaagaaaaattgagaatatttgcccaaaaggttactgacggggttttacgtatcagtactgacggagattctttgacccctgggattcgtcagttgacccattcaaatgaggcctatcgagttaaactgtcgtcaattaatgacaaacctagtcttttgtctaactttaaactttcaggcccagattttcaaaaggtctttcgtcaggaagtcttagaagcgaaaaaagaagggtttcaagatattctatttcatacagatggtttgatcagtgaattatcaatcggaaattttgtggcaaaaaaggggaatcagtacgaaacgccagccaaatatgctctaaaaggaacttttttagatttatttgcgaaaaatcatacgctaatatataaagatattgcgatttctgatttgaaaacttacgatcgtttttatatgacaaatgctgtcagaggattagttgaaataaaaattgatggaatttcctaataa
BBa_K909014_sequence
1
ttgacggctagctcagtcctaggtacagtgctagctactagagaaagaggagaaatactagatgaaggaatttataataaaaaatacggatatttggaaaattttcctaaaatattatcggtcagatgaagaaattgtttttttacatagtagtcaggtgaccgaaaatgagcattatagtattttagctcataaaccttataaaaaggtttcaaaatataagggtcaagtgttttttaatggtgaaaaaaagaagttcaattttttagatgcggtagatttgctgaaggatgagagagttgaacgacctaaaaattggcctttttatccagaattattgggttttgtaagttatgagcaagatccggcttgttttgcagcttatgatgaagttttactttttgaccatagaacaaaactgttacgtgtcgtgcaatttgaacaaactgatggccaatattggctgactgaatcggaagaaattgaagtggattcagagattgagttcgatgttcagaatggcataggggctgtttttattgaccaaacgaggcaagaatatattgcttcaataaaaaaaatacaagattatatgaaggctggcgatatttatgttgccaatttgacgcaacaatttgaaatttggtccgatcaaaaacctattgatgtttttaagaaaacaaggaaacaaattcctgctcctttctcatcatttttacaatatcctgaatggaaaatgacgcaaatttcaagttctgttgaacgctttgtttctattcataatggagcattaatttcaaaacccattaaaggaacaattgccagaggagaaaatgttgtagctgatagattacaaaagaaaatactttccgacagtagtaaagaacggtctgagttactgatggtgacggatttattgcgtaatgatattgcccgaattagtcaacctttttctttgtctgtccctaaatttgcagaaattgaaactttttctcatgttcatcaactggtgacttcaataaaaagtagaattaaagaagatttgactttttcagaatttatgacggctttatttccgggaggttcaatcacaggtacacctaagaagcgggcaatggagattattaaggaagttgaaaaacaacctagaggaatttatacagggatgcagggttggttaagtcgagaaatggatttggatatgaacatcgtgattcggacattagttcatgacggtgagcattatcagcttggtgtaggcggtggaattacgttcgagagcgaagcagaagcagagttttcagagattttactaaaagcaaaaccctttttagatatattaggcctgaaagatgttccaagtattttatttacaacaggccttgttaaaaatggtgaattgttaaatttagagggtcatgtcaatcgcttgaaaaaacaataccatcatgcagatttggaagaaaaattgagaatatttgcccaaaaggttactgacggggttttacgtatcagtactgacggagattctttgacccctgggattcgtcagttgacccattcaaatgaggcctatcgagttaaactgtcgtcaattaatgacaaacctagtcttttgtctaactttaaactttcaggcccagattttcaaaaggtctttcgtcaggaagtcttagaagcgaaaaaagaagggtttcaagatattctatttcatacagatggtttgatcagtgaattatcaatcggaaattttgtggcaaaaaaggggaatcagtacgaaacgccagccaaatatgctctaaaaggaacttttttagatttatttgcgaaaaatcatacgctaatatataaagatattgcgatttctgatttgaaaacttacgatcgtttttatatgacaaatgctgtcagaggattagttgaaataaaaattgatggaatttcctaataatactagagaaagaggagaaatactagatgaaattgctattaattgataattatgattcttttacttatttgcttgcacagtattttgaggaattagattgtagtgtaacagtggttaatgaccaagataaaatgagtcagaaaattagaatttctccggattttatttgtgaaaattatgatgcgattatcatttctccaggtccaaaaacaccaaaagaagccgtttttagtagggatgtagttcaactatacgctggaaaaattcctatgttaggaatttgcttgggtcagcaagtcattgctgaatgttttggaggaaatgttgttcttggtgagaggccaatgcatggaaaaatttctgtcattcgtcataattatcaaggaatttttaaaggacttccacaaaatttgaaagttgcacgttatcattcgttgattgtcgataaactacctgatgattttgaaattgatgcgcagagtgaggatggtgttattcaggccattcatcagccaaaattaaaattgtgggctttacaatttcacccagaaagtttagttactgaatatggtcatgaaatgttaaataattttttgaaagtggtgtaataatactagagccaggcatcaaataaaacgaaaggctcagtcgaaagactgggcctttcgttttatctgttgtttgtcggtgaacgctctctactagagtcacactggctcaccttcgggtgggcctttctgcgtttata
BBa_B0034_sequence
1
aaagaggagaaa
BBa_K137005_sequence
1
atgaaattgctattaattgataattatgattcttttacttatttgcttgcacagtattttgaggaattagattgtagtgtaacagtggttaatgaccaagataaaatgagtcagaaaattagaatttctccggattttatttgtgaaaattatgatgcgattatcatttctccaggtccaaaaacaccaaaagaagccgtttttagtagggatgtagttcaactatacgctggaaaaattcctatgttaggaatttgcttgggtcagcaagtcattgctgaatgttttggaggaaatgttgttcttggtgagaggccaatgcatggaaaaatttctgtcattcgtcataattatcaaggaatttttaaaggacttccacaaaatttgaaagttgcacgttatcattcgttgattgtcgataaactacctgatgattttgaaattgatgcgcagagtgaggatggtgttattcaggccattcatcagccaaaattaaaattgtgggctttacaatttcacccagaaagtttagttactgaatatggtcatgaaatgttaaataattttttgaaagtggtgtaataa
BBa_B0012_sequence
1
tcacactggctcaccttcgggtgggcctttctgcgtttata
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z