BBa_K917012
1
BBa_K917012
pLac promoter plus napC quinol dehydrogenase gene
2012-09-23T11:00:00Z
2015-05-08T01:13:46Z
pLac gene comes from E. coli BL21 genomic DNA
napC was cloned from Escherichia coli JM109 chromosome.
This part consists of the standard registry lac promoter (BBa_J33207) plus Escherichia coli tetraheme quinol dehydrogenase napC with native RBS (BBa_K917003).
false
false
_1182_
0
13804
9
In stock
true
no special notes
false
Jakub Krakowiak
component2195981
1
BBa_K917003
component2195977
1
BBa_J33207
annotation2195977
1
BBa_J33207
range2195977
1
1
600
annotation2195981
1
BBa_K917003
range2195981
1
609
1239
BBa_J33207
1
BBa_J33207
lac promoter and lacZ
2006-10-26T11:00:00Z
2015-08-31T04:08:46Z
The DNA was amplified from E. coli BL21 genomic DNA using primers based on published sequence (Genbank accession J01636, gi:146575). The annotation shown here is based on that associated with this Genbank entry. The sequence shown here is derived by sequencing the construct.
This part (submitted in pSB1A2) consists of the lac promoter and lacZ' gene, encoding the N-terminal 76 amino acid residues of LacZ, sufficient to complement the lacZ-delta-M15 mutation for blue-white selection on Xgal plates. A SacI site has been introduced at the 3' end, overlapping the XbaI site of the Biobrick prefix. This is designed to be used as a cloning vector for making new biobricks. PCR primers can be designed with a SacI site in one primer and an SpeI site in the other. This removes the necessity for an excessively long non-complementary tail on one primer bearing either the full biobrick prefix or suffix. The PCR product can then be digested with SacI and SpeI for insertion into this plasmid, replacing the Plac-lacZ' cassette. Recombinant plasmids will then be white on IPTG/Xgal plates, whereas any that still contain the original insert will be blue. We have used this strategy to prepare several biobricks, including BBa_J33204, which contains the xylE gene encoding catechol-2,3-dioxygenase. (For making biobricks that contain lacZ', BBa_J33204 can be used in the same way; in this case, clones with plasmids that still contain xylE will turn yellow on addition of a drop of 10 mM catechol.)
false
false
_63_
0
837
63
It's complicated
true
Note that the SacI site overlaps the SpeI site. The Biobrick prefix ends ...TCTAGAG. When this is added to the CTC at the start of the sequence shown here, the SacI site, GAGCTC, is generated.
false
Chris French
annotation1907859
1
-10
range1907859
1
320
325
annotation1907858
1
lacZ'
range1907858
1
370
600
annotation1907857
1
rbs
range1907857
1
359
362
annotation1907856
1
LacI binding site
range1907856
1
332
352
annotation1907860
1
-35
range1907860
1
297
302
annotation1907854
1
SacI
range1907854
1
1
3
annotation1907855
1
CAP binding site
range1907855
1
248
285
BBa_K917003
1
BBa_K917003
E coli quinol dehydrogenase napC
2012-08-09T11:00:00Z
2015-05-08T01:13:46Z
Escherichia coli JM109 chromosomal DNA
This part consists of Escherichia coli tetraheme quinol dehydrogenase napC with native RBS. NapC is located in the inner membrane and acts as part of E coli electron transport system.
false
false
_1182_
0
13804
9
In stock
true
Part obtained by PCR amplification of E coli JM109 gene
false
Jakub Krakowiak
annotation2179463
1
Start codon
range2179463
1
14
16
annotation2179465
1
RBS
range2179465
1
3
8
annotation2179464
1
Stop codon
range2179464
1
614
616
BBa_J33207_sequence
1
ctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtgaaattgtgagcggataacaatttcacacaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtga
BBa_K917003_sequence
1
ataagaggttattatgggaaattctgaccgtaagcctggtctgattaagcgcctgtggaaatggtggcgtacccccagccgtctggcgctggggacgctgctgttgatcggttttgttggcggcatcgtcttctggggtggctttaacaccgggatggaaaaagccaataccgaagagttctgcattagctgccacgaaatgcgcaacacggtgtatcaggaatacatggattccgtgcactacaacaaccgtagcggcgtccgtgcgacctgtccggattgtcacgttccgcacgagtttgtgccgaagatgatacgcaagctcaaagcaagtaaagagctgtatggtaaaatttttggcgttattgacacgccgcagaaatttgaagctcatcgtctgacgatggcacagaatgagtggcggcgcatgaaggacaataactcgcaggagtgccgtaactgtcacaacttcgagtatatggatacaaccgcccagaaatcggttgccgcgaagatgcatgaccaggcggtgaaagatgggcaaacctgtattgattgccataaagggatagcgcacaagctgcccgatatgcgtgaagtcgagccaggtttttaacagggttattgcgtg
BBa_K917012_sequence
1
ctcatgttatatcccgccgttaaccaccatcaaacaggattttcgcctgctggggcaaaccagcgtggaccgcttgctgcaactctctcagggccaggcggtgaagggcaatcagctgttgcccgtctcactggtgaaaagaaaaaccaccctggcgcccaatacgcaaaccgcctctccccgcgcgttggccgattcattaatgcagctggcacgacaggtttcccgactggaaagcgggcagtgagcgcaacgcaattaatgtgagttagctcactcattaggcaccccaggctttacactttatgcttccggctcgtatgttgtgtgaaattgtgagcggataacaatttcacacaggaaacagctatgaccatgattacggattcactggccgtcgttttacaacgtcgtgactgggaaaaccctggcgttacccaacttaatcgccttgcagcacatccccctttcgccagctggcgtaatagcgaagaggcccgcaccgatcgcccttcccaacagttgcgcagcctgaatggcgaatggcgctttgcctggtttccggcaccagaagcggtgccggaaagctggctggagtgatactagagataagaggttattatgggaaattctgaccgtaagcctggtctgattaagcgcctgtggaaatggtggcgtacccccagccgtctggcgctggggacgctgctgttgatcggttttgttggcggcatcgtcttctggggtggctttaacaccgggatggaaaaagccaataccgaagagttctgcattagctgccacgaaatgcgcaacacggtgtatcaggaatacatggattccgtgcactacaacaaccgtagcggcgtccgtgcgacctgtccggattgtcacgttccgcacgagtttgtgccgaagatgatacgcaagctcaaagcaagtaaagagctgtatggtaaaatttttggcgttattgacacgccgcagaaatttgaagctcatcgtctgacgatggcacagaatgagtggcggcgcatgaaggacaataactcgcaggagtgccgtaactgtcacaacttcgagtatatggatacaaccgcccagaaatcggttgccgcgaagatgcatgaccaggcggtgaaagatgggcaaacctgtattgattgccataaagggatagcgcacaagctgcccgatatgcgtgaagtcgagccaggtttttaacagggttattgcgtg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z