BBa_K957015
1
BBa_K957015
Naphthalene Dioxygenase (From Pseudomonas NAH7 plasmid)
2012-10-27T11:00:00Z
2015-05-08T01:13:49Z
Psueomonas putida NAH7 plasmid.
Provided by Dr. Eugene L. Madsen, Cornell University Department of Microbiology
When the nah operon from the NAH7 Pseudomonas plasmid is heterologously expressed in E. coli, the cells have the ability to synthesize indigo from tryptophan [1].
E. coli contains the enzyme tryptophanase, which splits the indole group from the peptide backbone. Naphthalene dioxygenase, from the nah operon, then creates a compound which will spontaneously eliminate water and be air oxidized into indigo as the final product.
[1] Ensley, B., Ratzkin, B., Osslund, T., Simon, M., Wackett, L., & Gibson, D. (1983). Expression of naphthalene oxidation genes in Escherichia coli results in the biosynthesis of indigo. Science, 222(4620), 167-9.
false
false
_1228_
0
13504
9
Not in stock
false
Internal PstI cutsite deleted w/ mutagenic PCR.
false
Dylan Patrick Webster
BBa_K957015_sequence
1
taagccggatttatggaacttctcatacagccaaacaatcgcctcattagctttagtcccggcgccaaccttctggaagtgcttcgcgaaaacggtgtcgctatttcctacagttgtatgtctgggcgttgcggaacctgccgctgtcgggttacagatggcagtgtaattgattcgggggcgggaagcgggttaccaaacctcgtggacgagcattatgtgctcgcctgtcagtcagtacttactcacaattgcgcgatcgaaatcccagaaaccgacgaaatcgtcacccacccggcgagaatcatcaagggcactgtggtcgccgtcgagtcgcccactcacgatatccgtcgcctacgcgtacgcctcgctaagcccttcgagttctcacccggacagtacgcgacattgcagttcagtcctgagcatgcgcgtccgtattcaatggcaggtctgccagatgaccaagaaatggagttccacatacgcaaggtgccgggtgggcgcgtaacggagtatgttttcgagcacgtccgcgaaggtacaagcatcaagttgagcgggccacttggtacggcttatttgcgtcagaaccacaccgggccgatgctctgtgtgggcggtgggaccggactagcaccggtgctgtcgattgttcgcggcgcgctgaagttgggtatgacaaaccccatcctcctttatttcggagtgcgcagtcagcaagacctctacgacgcagagcgattgcacaaactcgccgctgatcaccctcaactgaccgtacacacggtaatcgcaatgggcccgattaatgagagtcagcgagccggtctagttaccgatgtgatcgaaaaagacatcatttcgctggctgggtggagggcctacctgtgcggcgcaccagcgatggttgaagcgctttgcaccgttaccaagcatcttggaatatcacccgaacatatttatgccgatgccttctatcccggtggaatctgaatagtccctttccctgcacctctgtccatcgaggactcatcaggaggatactcaaataagcgcaaataataacagtcgcgtcagtatttgcggcagcgaaatggtttccctctccctcatttaccccatctgaggatagttttatgacagaaaaatggattgaagcagtcgccctttctgacatcccagaaggtgatgtcctcggcgtgactgtcgagggcaaggagctggcgttgtacgaagtggaaggcgaaatctacgctaccgacaacctgtgcacgcatggtgccgcccgcatgagcgatggttatctcgaggggcgagaaatcgaatgccccttgcatcaaggtcggtttgacgtttgtacaggcagagccctctgcgcccccgtgacagagaacatcaaaacatatgcagtcaagattgagaacctgcgcgtaatgattgatttgagcggagagttttaataggaggtaccccggaccctagcgcgtaactaccccaattccatcttttttaggtgaaaacatgaattacaaaaacaaaatattggtgagtgaatctgggctgacccaaaagcacctgattcatggcgatgaagaacttttccagcacgaactgagaaccatttttgcgcggaactggctttttctcactcatgacagcctgattccatcccccggcgactatgttaccgcaaaaatgggtattgacgaggtcatcgtctctcggcagagcgacggttcgattcgtgccttcctgaacgtttgtcggcaccgtggcaagacgctggttaacgcggaagccggcaatgccaaaggtttcgtttgcagctatcacggctggggcttcggctccaacggtgagctccagagcgttccattcgaaaaagagctgtacggcgagtcgctcaacaaaaaatgtctggggttgaaagaagtcgctcgcgtggagagcttccatggcttcatctatggttgcttcgatcaggaggcccctcctcttatggactatctgggtgacgctgcttggtacctagagcccatcttcaaacattcaggcggtttagaactggtcggtcctccaggcaaggttgtgatcaaggccaactggaaggcacccgcggaaaactttgtgggggatgcataccacgtgggttggacgcacgcgtcttcgcttcgctcgggagagtctatcttcgcgtcgctcgctggcaacgcagtgctgccccctgaaggtgcaggcttgcaaatgacctccaaatacggcagcggcatgggtgtgttgtgggacggatattcaggcgtgcatagcgcagacttggttccggagttgatggcattcggcggctctaagcaggaaaggctgaacaaagaaattggcgatgttcgcgcccggatttatcgcagccacctcaactgcaccgttttcccgaacaacagcatgctgacctgctcgggtgttttcaaagtatggaacccgatcgacgcaaacaccaccgaggtctggacctacgccattgtcgaaaaagacatgcccgaggatctcaagcgccgcttggccgactcggttcagcgtacgtttgggcctgctggcttctgggaaagcgacgacaatgacaatatggaaacagcgtcgcaaaacggcaagaaatatcaatccagagatagtgatctgctttcaaaccttggtttcggtaaggacgtatacggcgacgcggtctatcctggcgtcgtcggcaaatcggcgatcggcgagaccagttatcgtggtttctaccgggcttaccaggcacacgtcagcagctccaactgggctgagttcgaggatgcctctagtacttggcataccgaactgacgaagactactgatcgctaacagacgagtcgaccatgatgatcaatattcaagaagacaagctggtctccgcccacgacgcccaagagtttcttcgtttcttcaattgccacgacgcggctttgcaacaagaagccaccacgctgctgaaccgggaagcgcatctgttggacattcaggcttaccgggcttggttagagcactgcgtggggtcagaggttcaatatcaggtcatttcacgcgaactgcgcgccgcttccgagcgccgttataagctcaatgaagccatgaacgtttacaacgaaaattttcagcaactgaaagttcgaatcgagcatcaactggatccgcaaaactggagcaacagcccgaagctgcgctttactcgcttcatcaccaatgtccaggccgcaagggacgtagatgacgaagagctacttcacatccgctccaacgtcattctgcaccgggcacgacgtggcaatcaggtcgatgtcttctacgccgcccgggaagacaaatggaaacgtggcgaaggtggagtgcgaaaattggtccagcgattcgtggattacccagagcgcatacttcagacgcacaatctgatggtctttctgtgatccag
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z