BBa_K976000 1 FGFR-1 Fibroblast Growth Factor-1 Receptor Coding Sequence 2013-06-09T11:00:00Z 2015-05-08T01:13:49Z The part has been derived from a genomic sequence provisioned by the Ensembl Database. The Fibroblast Growth Factor-1 Receptor (FGFR-1) is a receptor that is commonly found in melanocytes and is involved with melanocyte differentiation, migration, and division. Malignant melanoma is characterized by abnormally high ligand expression of Fibroblast Growth Factor-2 (FGF2), otherwise known as the Basic Fibroblast Growth Factor (BFGF). The FGFR-1 receptor as a high affinity towards binding to the FGF2 ligand present upon the surface of potentially malignant melanocytes, and therefore may be utilized to detect presence of malignant melanoma tumor. false false _1269_ 0 15167 9 Not in stock false The start codon sequence has been added to the FGFR-1 coding sequence. false Amna Sohail annotation2329993 1 Ig-like C2-type 3 Domain range2329993 1 765 1071 annotation2329945 1 Cytoplasmic Domain range2329945 1 1194 2466 annotation2329943 1 Topological Extracellular Domain range2329943 1 66 1128 annotation2329994 1 Protein Kinase Domain range2329994 1 1434 2301 annotation2329946 1 Ig-like C2-type 1 Domain range2329946 1 75 357 annotation2329944 1 Helical Transmembrane Domain range2329944 1 1131 1191 annotation2329947 1 Ig-like C2-type 2 Domain range2329947 1 474 738 BBa_K976000_sequence 1 atgtggtcctggaaatgtttgttgttttgggcggtcttggtcaccgcgaccttgtgtaccgcgcgtccttcccctaccttgcctgagcaagcgcaaccttggggggcgcctgtcgaggtcgagtcctttttggtccatcctggggacttgttgcaattgcgttgtcgtttgcgtgacgacgtccaatccatcaactggttgcgtgacggggtccaattggcggagtccaaccgtacccgtatcaccggggaggaggtcgaggtccaagactccgtccctgcggactccgggttgtatgcgtgtgtcacctcctccccttccgggtccgacaccacctatttttccgtcaacgtctccgacgcgttgccttcctccgaggacgacgacgacgacgacgactcctcctccgaggagaaagaaaccgacaacaccaaacctaaccgtatgcctgtcgcgccttattggacctcccctgagaaaatggagaaaaaattgcatgcggtccctgcggcgaaaaccgtcaaatttaaatgtccttcctccgggacccctaaccctaccttgcgttggttgaaaaacgggaaagagtttaaacctgaccatcgtatcggggggtataaagtccgttatgcgacctggtccatcatcatggactccgtcgtcccttccgacaaagggaactatacctgtatcgtcgagaacgagtatgggtccatcaaccatacctatcaattggacgtcgtcgagcgttcccctcatcgtcctatcttgcaagcggggttgcctgcgaacaaaaccgtcgcgttggggtccaacgtcgagtttatgtgtaaagtctattccgaccctcaacctcatatccaatggttgaaacatatcgaggtcaacgggtccaaaatcgggcctgacaacttgccttatgtccaaatcttgaaaaccgcgggggtcaacaccaccgacaaagagatggaggtcttgcatttgcgtaacgtctcctttgaggacgcgggggagtatacctgtttggcggggaactccatcgggttgtcccatcattccgcgtggttgaccgtcttggaggcgttggaggagcgtcctgcggtcatgacctcccctttgtatttggagatcatcatctattgtaccggggcgtttttgatctcctgtatggtcgagtccgtcatcgtctataaaatgaaatccgggaccaaaaaatccgactttcattcccaaatggcggtccataaattggcgaaatccatccctttgcgtcgtcaagtcaccgtctccgcggactcctccgcgtccatgaactccggggtcttgttggtccgtccttcccgtttgtcctcctccgggacccctatgttggcgggagtctccgagtatgagttgcctgaggaccctcgttgggagttgcctcgtgaccgtttggtcttggggaaacctttgggggaggggtgttttgggcaagtcgtcttggcggaggcgatcgggttggacaaagacaaacctaaccgtgtcaccaaagtcgcggtcaaaatgttgaaatccgacgcgaccgagaaagacttgtccgacttgatctccgagatggagatgatgaaaatgatcgggaaacataaaaacatcatcaacttgttgggggcgtgtacccaagacgggcctttgtatgtcatcgtcgagtatgcgtccaaagggaacttgcgtgagtatttgcaagcgcgtcgtcctcctgggttggagtattgttataacccttcccataaccctgaggagcaattgtcctccaaagacttagtctcctgtgcgtatcaagtcgcgcgtgggatggagtatttggcgtccaaaaaatgtatccatcgtgacttggcggcgcgtaacgtcttggtcaccgaggacaacgtcatgaaaatcgcggactttgggttggcgcgtgacatccatcatatcgactattataaaaaaaccaccaacgggcgtttgcctgtcaaatggatggcgcctgaggcgttgtttgaccgtatctatacccatcaatccgacgtctggtcctttggggtcttgttgtgggaaatctttaccttgggggggtccccttatcctggggtccctgtcgaggagttgtttaaattgttgaaagaggggcatcgtatggacaaaccttccaactgtaccaacgagttgtatatgatgatgcgtgactgttggcatgcggtcccttcccaacgtcctacctttaaacaattggtcgaggacttggaccgtatcgtcgcgttgacctccaaccaagagtatttggacttgtccatgcctttggaccaatattccccttcctttcctgacacccgttcctccacctgttcctccggggaggactccgtcttttcccatgagcctttgcctgaggagccttgtttgcctcgtcatcctgcgcaattggcgaacggggggttgaaacgtcgt igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 James Alastair McLaughlin Chris J. Myers 2017-03-06T15:00:00.000Z