BBa_K976001 1 FRS2 Fibroblast Growth Factor Receptor Substrate 2 2013-06-19T11:00:00Z 2015-05-08T01:13:49Z Source: UniProt Database Organism: Homo sapiens The Fibroblast Growth Factor Receptor Substrate 2, or FRS2 protein is a lipid based membrane-anchored docking protein that forms a fusion protein complex with the Fibroblast Growth Factor Receptor-1 (FGFR-1) to regulate downstream signal transduction. In melanocytes, this docking protein mediates signal transduction to pathways as the MAPK pathway that are involved in melanocyte proliferation, differentiation, and migration. FRS2 may be useful in its ability to mediate downstream signaling as the FGF2 ligand binds to FGFR-1. false false _1269_ 0 15167 9 Not in stock false No particular design considerations were dealt with. false Amna Sohail BBa_K976001_sequence 1 atggggtcctgttgttcctgtcctgacaaagacaccgtccctgacaaccatcgtaacaaatttaaagtcatcaacgtcgacgacgacgggaacgagttggggtccgggatcatggagttgaccgacaccgagttgatcttgtatacccgtaaacgtgactccgtcaaatggcattatttgtgtttgcgtcgttatgggtatgactccaacttgttttcctttgagtccgggcgtcgttgtcaaaccgggcaagggatctttgcgtttaaatgtgcgcgtgcggaggagttgtttaacatgttgcaagagatcatgcaaaacaactccatcaacgtcgtcgaggagcctgtcgtcgagcgtaacaaccatcaaaccgagttggaggtccctcgtacccctcgtacccctaccacccctgggtttgcggcgcaaaacttgcctaacgggtatcctcgttatccttcctttggggacgcgtcctcccatccttcctcccgtcatccttccgtcgggtccgcgcgtttgccttccgtcggggaggagtccacccatcctttgttggtcgcggaggagcaagtccatacctatgtcaacaccaccggggtccaagaggagcgtaaaaaccgtacctccgtccatgtccctttggaggcgcgtgtctccaacgcggagtcctccacccctaaagaggagccttcctccatcgaggaccgtgaccctcaaatcttgttggagcctgagggggtcaaatttgtcttggggcctacccctgtccaaaaacaattgatggagaaagagaaattggagcaattggggcgtgaccaagtctccgggtccggggcgaacaacaccgagtgggacaccgggtatgactccgacgagcgtcgtgacgcgccttccgtcaacaaattggtctatgagaacatcaacgggttgtccatcccttccgcgtccggggtccgtcgtgggcgtttgacctccacctccacctccgacacccaaaacatcaacaactccgcgcaacgtcgtaccgcgttgttgaactatgagaacttgccttccttgcctcctgtctgggaggcgcgtaaattgtcccgtgacgaggacgacaacttggggcctaaaaccccttccttgaacgggtatcataacaacttggaccctatgcataactatgtcaacaccgagaacgtcaccgtccctgcgtccgcgcataaaatcgagtattcccgtcgtcgtgactgtacccctaccgtctttaactttgacatccgtcgtccttccttggagcatcgtcaattgaactatatccaagtcgacttggagggggggtccgactccgacaaccctcaaacccctaaaacccctaccacccctttgcctcaaacccctttgcgtcgtaccgagttgtatgcggtcatcgacatcgagcgtaccgcggcgatgtccaacttgcaaaaagcgttgcctcgtgacgacgggacctcccgtaaaacccgtcataactccaccgacttgcctatg igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z