BBa_M11005 1 BBa_M11005 comE3 Competence locus E from H. pylori 2009-04-11T11:00:00Z 2015-05-08T01:13:52Z This part is derived from the organism Helicobatcer pylori strain 26695, and is available as part of the complete Helicobacter genome. The reference sequence for this gene may be accessed on NCBI using the accession number: NP_208153. This coding region is responsible for the generation of a DNA binding competence protein suspected to be partly responsible for the natural competence and genetic diversity observed in Helicobacter Pylori strains. Knockout studies of this gene (HP ORF 1361) have demonstrated greatly diminished cell transformation capability when a mutated form of the comE3 gene is present (Yu-Ching Yeh et al., 2003). This gene could be useful in preparing organisms to be naturally competent for greater ease of genetic transformation studies/antibiotic resistance studies, particularly involving H. pylori. It is important to note, however, that this gene has been found to be lethal to E. coli when it is expressed (Yu-Ching Yeh et al., 2003). false false _302_ 0 4567 302 Not in stock false This sequence was not modified in any way from that given under the NCBI accession number of NP_208153. false Eric Monson annotation2002297 1 Stop range2002297 1 1252 1254 annotation2002296 1 Start range2002296 1 1 3 BBa_M11005_sequence 1 gtgtgtggggtgtttttaagccttttattggcgattaacctttatttagaatacttgaattaccaaaagcttgatttttcaaaacctacaagtttgagcgctcaaatcttgttgcaataccctaaaactaaagatcaaaaaacctattttgttttaaagctccaatcaaaaaacatgatcttttacaccaccattaaagagcctttaaaaaacctccaataccgccatgcgcaattttttggcaaaatcaaaccttgctcgttcttagagtctctaaaatcatgcttttttcaaacttattctttttctttaacacgaaaacaggatttcaaatcgcattggcgccatttcattgacagcgctcatgaaaacgctttggtgggtaatttatatcgcgcgttatttataggggatagcttaaataaagacttaagggatagggctaacgcgctagggatcaaccacttactagccattagcgggttccatttagggattttgagcgttagcgtgtattttctttcctctcttttttatacccccttacaaaaacgctatttcccttataggaacgctttttatgatataggggttttggtgtgggtttttttgctggggtatttgttgctactagattttttaccctcttttttcagggcgtttttaatgggcttattagggtttttggcatgcttttttggggtaaggcttttgagttttaaacttttgattttagcgtgctgtatcgccatagcgttactccctaaattgctttttagcgtggggtttttgctttctgtttgtggggtgtggtatatcttcttgtttttaaaacacactcaaattttttttaaaacctcttcttttttgatgcgatcttttcaagccataagcttaagcgcgctggtgtttttgaacatgctcattatcgtgcatgcctttttccctatgttttcgccctaccagctctttagcattcctttaggcttgatttttatcgtgtttttccctttgagtttgttcttgcatgcggtgggtttggggtctttgttggatcgccttttaagcatgcctttaacaatccctacgatttcggttccttcgcccttatggcttttaggggtgcatttatttttaacgattttaagcgcgcgtttttttaaagtttatttaagcatgaatgttttaagtgcgggctttttcttgtattgttgctatcaatatattataatgcctagcttaattgtaggttag igem2sbol 1 iGEM to SBOL conversion Conversion of the iGEM parts registry to SBOL2.1 Chris J. Myers James Alastair McLaughlin 2017-03-06T15:00:00.000Z