BBa_M13507
1
BBa_M13507
M13KO7 gene VII RBS
2006-12-14T12:00:00Z
2015-05-08T01:13:56Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban
This RBS is part of the bacteriophage M13 genome, initiating translation of the gene VII message (BBa_M13007). The part aligns with base pairs 1092-1107 in M13K07 genome. It was identified as the RBS for gene VII message by Wezenbeek et al in Gene (1980) 11: 129-148
false
true
_45_
0
314
1
Not in stock
false
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban
false
Natalie Kuldell
BBa_M31534
1
BBa_M31534
This is gene VII of M13K07 (RBS, and ORF)
2007-02-28T12:00:00Z
2015-05-08T01:14:00Z
Though the gene and its regulatory sequences exist in nature in M13K07, they do not yet exist in this separate form.
When designing a phage, it is much more practical and effective to think of DNA in functional units than strings of regulatory and coding regions. This part combines the transcriptional and translational regions with the ORF to form a functional (where function is defined as the output of the gene).
false
false
_102_
0
1380
102
Not in stock
false
When removed from its place in the genome that has been determined by evolution, we can't be sure the change will be tolerated. There may be cross-talk between copied and separated elements with significant homology. Because we have removed and maintained entire portions of genes in the formation of separate genomic entities, there is also the possibility of expression of these 'partial' genes. I will address this by placing transcriptional terminators and hair pins between genes.
false
Matt Gethers
component1917916
1
BBa_M13007
component1917915
1
BBa_M13507
annotation1917915
1
BBa_M13507
range1917915
1
1
16
annotation1917916
1
BBa_M13007
range1917916
1
23
124
BBa_M13007
1
BBa_M13007
M13K07 gene VII
2006-12-11T12:00:00Z
2015-05-08T01:13:55Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban.
This gene is part of the bacteriophage M13 genome. It encodes a protein that is presented with p9 to initiate phage assembly at the blunt end of the phage coat. Approximately 5 copies of each protein are presented on mature phage. Without p9 or p7, no phage is produced. p7 is one of the smallest ribosomally translated proteins with described function. It is hydrophobic and the N-terminus is negatively charged, suggesting a C-terminus inside orientation.
false
true
_45_
0
314
1
Not in stock
false
stop codon overlaps with p9 start codon in M13 genome.
false
Natalie Kuldell
BBa_M13007_sequence
1
atggagcaggtcgcggatttcgacacaatttatcaggcgatgatacaaatctccgttgtactttgtttcgcgcttggtataatcgctgggggtcaaagatga
BBa_M13507_sequence
1
gttccggctaagtaac
BBa_M31534_sequence
1
gttccggctaagtaactactagatggagcaggtcgcggatttcgacacaatttatcaggcgatgatacaaatctccgttgtactttgtttcgcgcttggtataatcgctgggggtcaaagatga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z