BBa_M13507
1
BBa_M13507
M13KO7 gene VII RBS
2006-12-14T12:00:00Z
2015-05-08T01:13:56Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban
This RBS is part of the bacteriophage M13 genome, initiating translation of the gene VII message (BBa_M13007). The part aligns with base pairs 1092-1107 in M13K07 genome. It was identified as the RBS for gene VII message by Wezenbeek et al in Gene (1980) 11: 129-148
false
true
_45_
0
314
1
Not in stock
false
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban
false
Natalie Kuldell
BBa_M13509
1
BBa_M13509
M13Ko7 gene IX RBS
2006-12-14T12:00:00Z
2015-05-08T01:13:56Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban
This RBS is part of the bacteriophage M13 genome, initiating translation of the gene IX message (BBa_M13009). The part aligns with base pairs 1190-1205 in M13K07 genome. It was identified as the RBS for gene IX message by Wezenbeek et al in Gene (1980) 11: 129-148
false
false
_45_
0
314
1
Not in stock
false
none
false
Natalie Kuldell
BBa_M13007
1
BBa_M13007
M13K07 gene VII
2006-12-11T12:00:00Z
2015-05-08T01:13:55Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban.
This gene is part of the bacteriophage M13 genome. It encodes a protein that is presented with p9 to initiate phage assembly at the blunt end of the phage coat. Approximately 5 copies of each protein are presented on mature phage. Without p9 or p7, no phage is produced. p7 is one of the smallest ribosomally translated proteins with described function. It is hydrophobic and the N-terminus is negatively charged, suggesting a C-terminus inside orientation.
false
true
_45_
0
314
1
Not in stock
false
stop codon overlaps with p9 start codon in M13 genome.
false
Natalie Kuldell
BBa_M31539
1
BBa_M31539
These are the genes in M13K07 responsible for forming the 'tip' of the phage.
2007-02-28T12:00:00Z
2015-05-08T01:14:00Z
Though the genes exist in nature in M13K07, they do not yet exist in this separate form.
These are the genes in M13K07 responsible for forming the 'tip' of the phage.
false
false
_102_
0
1380
102
Not in stock
false
This abstraction is useful for analysis of complex functions, but there are still interactions at the base pair level that need to be resolved before it can be implemented.
false
Matt Gethers
component2220337
1
BBa_M31535
component2220334
1
BBa_M31534
annotation2220337
1
BBa_M31535
range2220337
1
125
239
annotation2220334
1
BBa_M31534
range2220334
1
1
124
BBa_M31535
1
BBa_M31535
This is gene IX of M13K07 (RBS, and ORF)
2007-02-28T12:00:00Z
2015-05-08T01:14:00Z
Though the gene and its regulatory sequences exist in nature in M13K07, they do not yet exist in this separate form.
When designing a phage, it is much more practical and effective to think of DNA in functional units than strings of regulatory and coding regions. This part combines the transcriptional and translational regions with the ORF to form a functional (where function is defined as the output of the gene).
false
true
_102_
0
1380
102
Not in stock
false
When removed from its place in the genome that has been determined by evolution, we can't be sure the change will be tolerated. There may be cross-talk between copied and separated elements with significant homology. Because we have removed and maintained entire portions of genes in the formation of separate genomic entities, there is also the possibility of expression of these 'partial' genes. I will address this by placing transcriptional terminators and hair pins between genes.
false
Matt Gethers
component1917942
1
BBa_M13009
component1917941
1
BBa_M13509
annotation1917942
1
BBa_M13009
range1917942
1
17
115
annotation1917941
1
BBa_M13509
range1917941
1
1
16
BBa_M31534
1
BBa_M31534
This is gene VII of M13K07 (RBS, and ORF)
2007-02-28T12:00:00Z
2015-05-08T01:14:00Z
Though the gene and its regulatory sequences exist in nature in M13K07, they do not yet exist in this separate form.
When designing a phage, it is much more practical and effective to think of DNA in functional units than strings of regulatory and coding regions. This part combines the transcriptional and translational regions with the ORF to form a functional (where function is defined as the output of the gene).
false
false
_102_
0
1380
102
Not in stock
false
When removed from its place in the genome that has been determined by evolution, we can't be sure the change will be tolerated. There may be cross-talk between copied and separated elements with significant homology. Because we have removed and maintained entire portions of genes in the formation of separate genomic entities, there is also the possibility of expression of these 'partial' genes. I will address this by placing transcriptional terminators and hair pins between genes.
false
Matt Gethers
component1917915
1
BBa_M13507
component1917916
1
BBa_M13007
annotation1917915
1
BBa_M13507
range1917915
1
1
16
annotation1917916
1
BBa_M13007
range1917916
1
23
124
BBa_M13009
1
BBa_M13009
M13K07 gene IX
2006-12-11T12:00:00Z
2015-05-08T01:13:55Z
New England Biolabs M13K07. Sequenced in 2002 by L. Panganaban.
This gene is part of the bacteriophage M13 genome. It encodes a protein that is presented with p7 to initiate phage assembly at the blunt end of the phage coat. Approximately 5 copies of each protein are presented on mature phage. In the absence of p9 or p7, no phage is produced. p9 is one of the smallest ribosomally translated proteins with described function. N-terminal display is possible, and some positively charged residues are seen at the C-terminal end of the protein, suggesting a "C-terminus inside" orientation.
false
true
_45_
0
314
1
Not in stock
false
start codon overlaps with stop codon of g7 upstream and
stop codon overlaps with start codon of g8 downstream.
false
Natalie Kuldell
BBa_M31539_sequence
1
gttccggctaagtaactactagatggagcaggtcgcggatttcgacacaatttatcaggcgatgatacaaatctccgttgtactttgtttcgcgcttggtataatcgctgggggtcaaagatgatcgctgggggtcaaagatgagtgttttagtgtattctttcgcctctttcgttttaggttggtgccttcgtagtggcattacgtattttacccgtttaatggaaacttcctcatga
BBa_M13007_sequence
1
atggagcaggtcgcggatttcgacacaatttatcaggcgatgatacaaatctccgttgtactttgtttcgcgcttggtataatcgctgggggtcaaagatga
BBa_M31535_sequence
1
tcgctgggggtcaaagatgagtgttttagtgtattctttcgcctctttcgttttaggttggtgccttcgtagtggcattacgtattttacccgtttaatggaaacttcctcatga
BBa_M13009_sequence
1
atgagtgttttagtgtattctttcgcctctttcgttttaggttggtgccttcgtagtggcattacgtattttacccgtttaatggaaacttcctcatga
BBa_M13507_sequence
1
gttccggctaagtaac
BBa_M13509_sequence
1
tcgctgggggtcaaag
BBa_M31534_sequence
1
gttccggctaagtaactactagatggagcaggtcgcggatttcgacacaatttatcaggcgatgatacaaatctccgttgtactttgtttcgcgcttggtataatcgctgggggtcaaagatga
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z