BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_M33353
1
BBa_M33353
CDS for TodT protein
2010-06-05T11:00:00Z
2015-05-08T01:14:02Z
This is a genomic sequence from Pseudomonas putida. The was obtained from GenBank (Y18245.1; http://www.ncbi.nlm.nih.gov/nuccore/4914628).
Pseudomonas putida possesses a two-component regulatory system (TCS) which can sense changes in the toluene level of the environment. TodS and TodT proteins control the expression of genes involved in the degradation of toluene, benzene, and ethylbenzene via the toluene dioxygenase pathway. In response to toluene and other aromatic hydrocarbons, the TodS/TodT TCS mediate a single promoter termed pTod, which transcribes the catabolic genes involved in the toluene dioxygenase pathway. TodT is phosphorylated by the protein kinase TodS, and it can also increase the autophosphorylation activity of TodS. Once TodT is activated, it binds to a site on the pTod promoter approximately 107 base pairs upstream from the RNA polymerase-binding site. DNA bending caused by integration host factor (IHF) enables contact between TodT and RNA polymerase, initiating transcription.
This part should be used in conjunction with BBa_M33351, the Ptod promoter, and BBa_M33350/BBa_M33352, the todS protein sequence.
false
false
_577_
0
6925
9
Not in stock
false
Restriction sites for EcorI, XbaI, SpeI, and PstI were removed from the sequence.
false
Alejandro Virrueta
annotation2070243
1
todT
range2070243
1
1
684
BBa_M33354
1
BBa_M33354
RBS+CDS for TodT protein
2010-06-05T11:00:00Z
2015-05-08T01:14:02Z
This is a genomic sequence from Pseudomonas putida. The was obtained from GenBank at http://www.ncbi.nlm.nih.gov/nuccore/4914628 (Y18245.1; todT coordinates: 14162..14845).
Pseudomonas putida possesses a two-component regulatory system (TCS) which can sense changes in the toluene level of the environment. TodS and TodT proteins control the expression of genes involved in the degradation of toluene, benzene, and ethylbenzene via the toluene dioxygenase pathway. In response to toluene and other aromatic hydrocarbons, the TodS/TodT TCS mediate a single promoter termed pTod, which transcribes the catabolic genes involved in the toluene dioxygenase pathway. TodT is phosphorylated by the protein kinase TodS, and it can also increase the autophosphorylation activity of TodS. Once TodT is activated, it binds to a site on the pTod promoter approximately 107 base pairs upstream from the RNA polymerase-binding site. DNA bending caused by integration host factor (IHF) enables contact between TodT and RNA polymerase, initiating transcription.
This part should be used in conjunction with BBa_M33351, the Ptod promoter, and BBa_M33350/BBa_M33352, the todS protein sequence.
false
false
_577_
0
6925
9
Not in stock
false
Made 1 silent mutation for XbaI, to ensure compliance with Assembly Standard 10. We also modified the stop codon to TAA, and added a strong ribosome binding site (BBa_B0034).
false
Alejandro Virrueta
component2070245
1
BBa_B0034
component2070247
1
BBa_M33353
annotation2070247
1
BBa_M33353
range2070247
1
19
702
annotation2070245
1
BBa_B0034
range2070245
1
1
12
BBa_B0034_sequence
1
aaagaggagaaa
BBa_M33353_sequence
1
atgcccgcccgctgggggtgcttgtttcctggtaagtatccctgccagacagggctccggcacatgagtgatcgggcatctgttatctatatcctcgatgacgacaatgcagtactggaagcactgagcagcttggtgcgttcaatcggcctgagtgtcgagtgtttttcatccgctagcgtattcctgaacgatgtcaatcgctctgcctgtggctgtctaattttggatgtccgtatgcccgagatgagcgggttggatgtgcaacgacaactgaaagagcttggcgagcaaatccccattatttttatcagcggccacggtgatattccgatggcagtcaaagcgatcaaggcgggtgcggtagacttcttcactaaaccttttcgagaagaggagctgcttggcgctattcgcgccgcgctgaagttggcgccccagcagagatcaaacgctccccgagtcagcgagcttaaagagaattacgaaagcctcagcaaacgcgagcaacaggtgcttaagttcgtcttgcgaggatatctaaacaagcagacggccctagagcttgatatatcggaagcaacagtgaaagtgcaccgccataatatcatgaggaaaatgaaagtatcttcaatccaggatctggttcgagtaactgagcggctcaaggatagcctggaataa
BBa_M33354_sequence
1
aaagaggagaaatactagatgcccgcccgctgggggtgcttgtttcctggtaagtatccctgccagacagggctccggcacatgagtgatcgggcatctgttatctatatcctcgatgacgacaatgcagtactggaagcactgagcagcttggtgcgttcaatcggcctgagtgtcgagtgtttttcatccgctagcgtattcctgaacgatgtcaatcgctctgcctgtggctgtctaattttggatgtccgtatgcccgagatgagcgggttggatgtgcaacgacaactgaaagagcttggcgagcaaatccccattatttttatcagcggccacggtgatattccgatggcagtcaaagcgatcaaggcgggtgcggtagacttcttcactaaaccttttcgagaagaggagctgcttggcgctattcgcgccgcgctgaagttggcgccccagcagagatcaaacgctccccgagtcagcgagcttaaagagaattacgaaagcctcagcaaacgcgagcaacaggtgcttaagttcgtcttgcgaggatatctaaacaagcagacggccctagagcttgatatatcggaagcaacagtgaaagtgcaccgccataatatcatgaggaaaatgaaagtatcttcaatccaggatctggttcgagtaactgagcggctcaaggatagcctggaataa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z