BBa_M36221
1
arsB
Ars B gene
2011-12-06T12:00:00Z
2015-05-08T01:14:03Z
fd
Arsenite permease, inner membrane protein responsible for forming the anion-conducting channel
false
false
_848_
0
11057
9
Not in stock
false
nbn
false
Lan Terry Xu, Martha Roman, Cyonna Holmes
annotation2166445
1
Restriction Site BsmBI
range2166445
1
268
274
annotation2166447
1
Restriction Site BsaI
range2166447
1
735
741
annotation2166412
1
start codon ATG
range2166412
1
1
3
BBa_B1002
1
BBa_B1002
Terminator (artificial, small, %T~=85%)
2006-08-29T11:00:00Z
2015-08-31T04:07:21Z
antiquity
Artifical terminator, estimated %T~=85
false
true
_41_
0
745
41
In stock
false
Bidirectional, with the reverse estimated to be less effective than the forward. Has a polyA tail of 6 residues.
true
Haiyao Huang
annotation1898415
1
Poly A tail
range1898415
1
4
9
annotation1898414
1
Poly A tail
range1898414
1
25
31
annotation1898413
1
stem loop
range1898413
1
10
25
annotation1898412
1
B1002
range1898412
1
1
34
BBa_M36220
1
arsA
arsA gene
2011-12-06T12:00:00Z
2015-05-08T01:14:03Z
Genecopoeia. http://www.genecopoeia.com/gene/hs-asna1.html 27 October 2011.
This part, ArsA, comes from a homolog optimized for Homo sapien
jaDHKSGdf
false
false
_848_
0
11057
9
Not in stock
false
asdgdfhfh
false
Designed by Terry Xu, Martha Roman, Cyonna Holmes
annotation2166411
1
Start codon ATG
range2166411
1
1
3
annotation2166446
1
Mutation: Restriction site BsmbI removal
range2166446
1
475
480
annotation2166444
1
Mutation:Restriction site BbsI removal
range2166444
1
313
318
BBa_M36222
1
BBa_M36222
ArsAction: Arsenite Removal Device (input: PoPs Signal, output: removal device)
2011-12-06T12:00:00Z
2015-05-08T01:14:04Z
asfasdfasdfas
The arsenic removal device is designed to prolong cell survival and decrease the rate of cell death due to arsenite toxicity. Our device does this by removing arsenite from the comprimsed cell using a two part removal method. The first coding sequence, arsA, is an ATPase that localizes to the membrane of the cell and confers energy to ArsB. ArsB uses this energy to form an ion efflux pump designed to drive arsenite out of the cell. This device is to be used as an actuator and it responds to the universal PoPs signal. The genes used are specific to the arsenic family and can only be used to create a pump that removes the ion form of arsenic (arsenite).
false
false
_848_
0
11057
9
Not in stock
false
In designing this part, we had to take into consideration the form of arsenic we wanted to remove. Removing arsenic from a cell called for the insertion of another coding sequence that coded for the gene, arsC. This addition would have significantly increased the total base pair count of our device. Instead, we decided to have our device remove arsenite. Furthermore, the ars family of genes is usually regulated by the arsR operon, but we did not including a coding sequence for arsR in our design. Because we designed our actuator to respond to the PoPS signal, we decided that inclusion of the arsR operon as a regulatory operon would be redundant. Therefore, we removed it.
Also, it was necessary to codon optimize each part of our device in order to ensure successful transformation and use in the K-12 strain of E. Coli.
false
Designed by Cyonna Holmes, Martha Roman, Terry Xu
component2166693
1
BBa_B1002
component2166684
1
BBa_B0035
component2166679
1
BBa_B0034
component2166688
1
BBa_M36221
component2166683
1
BBa_M36220
annotation2166684
1
BBa_B0035
range2166684
1
1227
1240
annotation2166688
1
BBa_M36221
range2166688
1
1247
2512
annotation2166693
1
BBa_B1002
range2166693
1
2521
2554
annotation2166683
1
BBa_M36220
range2166683
1
19
1218
annotation2166679
1
BBa_B0034
range2166679
1
1
12
BBa_B0035
1
BBa_B0035
RBS (B0030 derivative)
2004-01-27T12:00:00Z
2015-08-31T04:07:20Z
-- No description --
false
false
_1_
0
24
7
Not in stock
false
false
Jason Kelly
BBa_B0034
1
BBa_B0034
RBS (Elowitz 1999) -- defines RBS efficiency
2003-01-31T12:00:00Z
2015-08-31T04:07:20Z
Released HQ 2013
RBS based on Elowitz repressilator.
false
true
_1_
0
24
7
In stock
false
Varies from -6 to +1 region from original sequence to accomodate BioBricks suffix. <p>No secondary structures are formed in the given RBS region. Users should check for secondary structures induced in the RBS by upstream and downstream elements in the +50 to -50 region, as such structures will greatly affect the strength of the RBS.
Contact info for this part: <a href="mailto:(bchow@media.mit.edu)">Brian Chow</a>
true
Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr IAP, 2003.
annotation23325
1
conserved
range23325
1
5
8
BBa_B1002_sequence
1
cgcaaaaaaccccgcttcggcggggttttttcgc
BBa_B0034_sequence
1
aaagaggagaaa
BBa_B0035_sequence
1
attaaagaggagaa
BBa_M36221_sequence
1
atgctgctggcgggtgctatcttcgtgctgactatcgttctggtgatttggcagccgaaaggtctgggcattggctggtcggcgactctgggcgctgtgctggctctggtgaccggcgtggtgcacccgggtgacatcccagtagtttggaacatcgtatggaatgccacggcggcttttattgcggttattatcatctccctgctgttggacgaaagcggtttcttcgaatgggctgccctgcagcgttggggtaacggtcgtgggcttttcacctggattgtgctgctgggcgcggccgttgcagcgctgtttgcgaacgatggtgctgcactgattctgaccccgatcgtcattgcgacgctgctggagctgggtttctcgaaaggtactaccctggcgttcgtaatggctgcgggctttatcgcggacactgcatctttaccgctgatcgtatctaacctggtgagcatcgtatctgcggacttcttcggcctgggttttcgcgagtacgcttctgtaatggtcccagtggacattgctgcaatcgttgcgactctcgtgatgctgcacctgtacttccgtaaggatatccctcagaactacgatatggcactgctgaaatcgccggcggaggctatcaaagatccggctacgttcaagacgggttgggtcgtactgctgctcctgctggtaggtcttttcgtgcttgaaccgctgggtatccctgcaatcgcagcggtaggtgcgctgatccttttcgttgtcgcaaaacgcggccacgctatcaacactggcaaggtactgcgtggtgctccgtggcagattgtgatcttctctctgggtatgtatcttgtcgtgtacggcctgcgtaacgcgggactgactgagtacctgtccggcgtgctgaacgttctggccgacaacggtctgtgggctgccactctgggcactggtttcctgaccgcgttcctgtcgagcattatgaacaacatgccgacggtgctggttggtgccctgtccattgacggctcaactgcgtccggtgtgatcaaagaagcgatggtatacgcaaacgtgatcggttgcgatttgggcccgaaaatcactccaattggttctctggcgaccctgctgtggctgcacgtactttcccagaaaaacatgaccatcagctggggttattactttcgtaccgggattatcatgacccttccagtactgttcgttactctggccgcgctggcgctctccttcactctgtaa
BBa_M36220_sequence
1
atgctgctcgatgtagaaccgctggaaccgaccctctcgaacattatcgagcagcgctctcttaaatggatcttcgttggcggtaaaggtggcgtaggtaagaccacctgctcttgctctctggcagttcagctgtccaaaggtcgcgagtccgtgctcatcatctcgaccgatccggcccacaacatttcggacgcgttcgatcagaaatttagtaaagttccaaccaaggttaagggctacgataacctctttgctatggagatcgacccaagcctcggtgtcgcggatgtgccggacgaattcttcgagaacatgctgtctatgggaaaaaaaatgatgcaggaggcaatgtccgcgttcccgggtatcgatgaagccatgagctacgcggaagtcatgcgtctggttaaaggtatgaacttcagcgttgtggtattcgataccgcgccaaccggtcataccctgctgaatttcccgaccattgttgaacgtggtctgggtcgcctgatgcagatcaaaaatcagatcagtccattcatttcacagatgtgcaacatgctgggtctgggtgacatgaacgcggatcagcttgcatccaaactggaggaaacccttcctgttatccgtagcgttagcgaacaatttaaagatccggaacaaacgacttttatttgcgtttgtatcgcggaattcctgtccctgtacgaaaccgaacgtctgatccaggaactggccaaatgtaaaattgacacccataacatcatcgtaaatcagctggtgttccctgacccggaaaaaccgtgcaaaatgtgtgaagcccgtcataagatccaggccaagtaccttgaccagatggaagatttgtacgaagatttccacatcgtgaagctgccgctgctgccgcacgaagttcgcggcgcggacaaagttaacactttctctgcgctgctgttagaaccgtacaaaccgccgtctgcgcagtagcacagctgccaaccgcagccactgccttttcatactcacccgccgcctagcccaccgccgcatggccgcgtgtgtaccaaatccccgccgtaataccgtggcagtcacctgggccgtcgtcaaggtggtgtacactcaccgtggtgggggtggtggggcgcggtagtggccccgtatctgtctcacctgctgctgtttaacaaatgaagttaa
BBa_M36222_sequence
1
aaagaggagaaatactagatgctgctcgatgtagaaccgctggaaccgaccctctcgaacattatcgagcagcgctctcttaaatggatcttcgttggcggtaaaggtggcgtaggtaagaccacctgctcttgctctctggcagttcagctgtccaaaggtcgcgagtccgtgctcatcatctcgaccgatccggcccacaacatttcggacgcgttcgatcagaaatttagtaaagttccaaccaaggttaagggctacgataacctctttgctatggagatcgacccaagcctcggtgtcgcggatgtgccggacgaattcttcgagaacatgctgtctatgggaaaaaaaatgatgcaggaggcaatgtccgcgttcccgggtatcgatgaagccatgagctacgcggaagtcatgcgtctggttaaaggtatgaacttcagcgttgtggtattcgataccgcgccaaccggtcataccctgctgaatttcccgaccattgttgaacgtggtctgggtcgcctgatgcagatcaaaaatcagatcagtccattcatttcacagatgtgcaacatgctgggtctgggtgacatgaacgcggatcagcttgcatccaaactggaggaaacccttcctgttatccgtagcgttagcgaacaatttaaagatccggaacaaacgacttttatttgcgtttgtatcgcggaattcctgtccctgtacgaaaccgaacgtctgatccaggaactggccaaatgtaaaattgacacccataacatcatcgtaaatcagctggtgttccctgacccggaaaaaccgtgcaaaatgtgtgaagcccgtcataagatccaggccaagtaccttgaccagatggaagatttgtacgaagatttccacatcgtgaagctgccgctgctgccgcacgaagttcgcggcgcggacaaagttaacactttctctgcgctgctgttagaaccgtacaaaccgccgtctgcgcagtagcacagctgccaaccgcagccactgccttttcatactcacccgccgcctagcccaccgccgcatggccgcgtgtgtaccaaatccccgccgtaataccgtggcagtcacctgggccgtcgtcaaggtggtgtacactcaccgtggtgggggtggtggggcgcggtagtggccccgtatctgtctcacctgctgctgtttaacaaatgaagttaatactagagattaaagaggagaatactagatgctgctggcgggtgctatcttcgtgctgactatcgttctggtgatttggcagccgaaaggtctgggcattggctggtcggcgactctgggcgctgtgctggctctggtgaccggcgtggtgcacccgggtgacatcccagtagtttggaacatcgtatggaatgccacggcggcttttattgcggttattatcatctccctgctgttggacgaaagcggtttcttcgaatgggctgccctgcagcgttggggtaacggtcgtgggcttttcacctggattgtgctgctgggcgcggccgttgcagcgctgtttgcgaacgatggtgctgcactgattctgaccccgatcgtcattgcgacgctgctggagctgggtttctcgaaaggtactaccctggcgttcgtaatggctgcgggctttatcgcggacactgcatctttaccgctgatcgtatctaacctggtgagcatcgtatctgcggacttcttcggcctgggttttcgcgagtacgcttctgtaatggtcccagtggacattgctgcaatcgttgcgactctcgtgatgctgcacctgtacttccgtaaggatatccctcagaactacgatatggcactgctgaaatcgccggcggaggctatcaaagatccggctacgttcaagacgggttgggtcgtactgctgctcctgctggtaggtcttttcgtgcttgaaccgctgggtatccctgcaatcgcagcggtaggtgcgctgatccttttcgttgtcgcaaaacgcggccacgctatcaacactggcaaggtactgcgtggtgctccgtggcagattgtgatcttctctctgggtatgtatcttgtcgtgtacggcctgcgtaacgcgggactgactgagtacctgtccggcgtgctgaacgttctggccgacaacggtctgtgggctgccactctgggcactggtttcctgaccgcgttcctgtcgagcattatgaacaacatgccgacggtgctggttggtgccctgtccattgacggctcaactgcgtccggtgtgatcaaagaagcgatggtatacgcaaacgtgatcggttgcgatttgggcccgaaaatcactccaattggttctctggcgaccctgctgtggctgcacgtactttcccagaaaaacatgaccatcagctggggttattactttcgtaccgggattatcatgacccttccagtactgttcgttactctggccgcgctggcgctctccttcactctgtaatactagagcgcaaaaaaccccgcttcggcggggttttttcgc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
James Alastair McLaughlin
Chris J. Myers
2017-03-06T15:00:00.000Z