BBa_M36265
1
BBa_M36265
qsc102 promoter
2014-10-22T11:00:00Z
2015-05-08T01:14:04Z
The promoter sequence was obtained from Figure 3 of this paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC95443/pdf/jb005529.pdf
Quorum sensing is a system bacteria use to coordinate behaviors that correlate to cell density. Each species of bacteria produces and senses a unique, diffusable small molecule. This allows bacteria to "count" how many cells of their species are in the vicinity. Pseudomonas Aeruginosa, an opportunistic human pathogen associated with cystic fibrosis, uses two quorum sensing systems, with one of them being LasI/LasR. When LasR interacts with N-(3-oxododecanoyl)-homoserine lactone which is produced by LasI, the complex binds to the promoter of the qsc102 gene and increases expression.
false
false
_848_
0
24142
9
Not in stock
false
N/A
false
Diana Gong
annotation2429161
1
qsc102 promoter
range2429161
1
1
67
BBa_M36265_sequence
1
acctgcccggaagggcaggttgtccctgccgggctgtgacaatttaattcgaccaggcatttcattg
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z