BBa_M36291
1
BBa_M36291
Transcription terminator (apFAB391) (99% efficient)
2011-12-09T12:00:00Z
2015-05-08T01:14:04Z
BIOFAB.org
This part is a transcription terminator.
false
false
_848_
0
11080
9
Not in stock
false
none.
false
Victoria Robles, Kyung Ri Park, Ken Xiong
BBa_M36363
1
BBa_M36363
PoPS -> DbjA
2013-10-24T11:00:00Z
2015-05-08T01:14:04Z
DbjA haloalkane dehalogenase is from the Bradyrhizobium japonicum USDA110 genome. The 5' BCD UTR and terminator are both from the BIOFAB database.
This composite part is an actuator that converts PoPS into production of the DbjA haloalkane dehalogenase. This device has a low strength 5' BCD UTR and a strong terminator.
false
false
_848_
0
19036
9
Not in stock
false
The 5' BCD UTR was not originally intended to be weak, but an error in selection led to the use of the incorrect BCD part.
false
Will Connors, Ethan Li, and Shirbi Ish-Shalom
component2370621
1
BBa_M36361
component2370622
1
BBa_M36362
component2370623
1
BBa_M36291
annotation2370623
1
BBa_M36291
range2370623
1
1031
1112
annotation2370621
1
BBa_M36361
range2370621
1
1
83
annotation2370622
1
BBa_M36362
range2370622
1
90
1022
BBa_M36361
1
BBa_M36361
5' Bicistronic UTR (apFAB866, GENE10_BCD2), No ATG Start
2013-10-24T11:00:00Z
2015-05-08T01:14:04Z
This part was sourced from the Supplemental Table 1 of Mutalik, et al., where it was constructed as a candidate sequence-independent BCD.
5' UTR based on bicistronic junction architecture, composed of a GENE10 SD1 context and a BCD2 SD2 region. Has low strength.
false
false
_848_
0
19036
9
Not in stock
false
This sequence was copied verbatim.
false
Ethan Li
BBa_M36362
1
BBa_M36362
DbjA Haloalkane Dehalogenase
2013-10-24T11:00:00Z
2015-05-08T01:14:04Z
This part was sourced from the genomic sequence of the soil bacterium Bradyrhizobium japonicum USDA110, at Accession NP_767727 and Gene ID 27376198. No mutations were made.
This part encodes an enzyme with dehalogenase activity for haloalkane substrates. DbjA catalyzes the cleavage of carbon-halogen bonds to form a primary alcohol and a halide. DbjA generally has higher overall activity than other haloalkane dehalogenases. Unlike most other known haloalkane dehalogenases, DbjA has very high activity on 2-bromo-1-chloropropane and chlorocyclopentane, and it has significant activity towards 1,2-dichloropropane (http://www.biochemj.org/bj/435/0345/bj4350345.htm).
ATG and TAA stop codons are included, so this part can just be flanked by a 5' UTR translation initiator and a 3' transcription terminator for use.
false
false
_848_
0
19036
9
Not in stock
false
The amino acid sequence was backtranslated through Gene Designer's genetic algorithm (Maximum Generations: 100; Maximum Mutation Rate: 0.05; Minimum Best Individual Selection Rate: 0.9; Population Size: 50; Number of Progeny: 25) into a codon set optimized for Escherichia coli K12. This algorithm was given additional parameters to avoid BbsI, BsmBI, and BsaI restriction sites (at a weight of 1), hairpins (at a weight of 1), and repeats of at least 10 bp (at a weight of 1). A TAA stop codon was then added at the end of the resulting DNA sequence.
false
Will Connors, Ethan Li, and Shirbi Ish-Shalom
BBa_M36361_sequence
1
aataattttgtttaactttaagaaggaggtatatccatggctagcatgactaaacatcttaatcatgctaaggaggttttcta
BBa_M36362_sequence
1
atgtctaaaccgattgaaattgagattcggcgtgctccggtcttgggcagctcgatggcctatcgtgagactggtgcacaggatgctcccgttgtgctgttcctccacggcaatccgacctctagccatatttggcgcaacatcctgccactggttagtcccgttgctcactgcattgcgccggatctgattggtttcggccaatccggtaaaccggatattgcgtaccgctttttcgaccatgtccgttatttagacgcctttatcgaacagcgcggcgttacatcagcatatctggtggcgcaggactggggtaccgcgctggcgtttcatctggcagcgcgccgccccgactttgttcgtggactcgcctttatggaattcattcgcccgatgccgacgtggcaggacttccaccatacagaagtggccgaggaacaggatcacgcggaagctgcccgtgctgtgtttcgaaaattccgcacgccgggagagggagaagcaatgattcttgaagcaaacgccttcgtcgaaagggtgttaccgggcggcatcgtacgcaaactgggtgacgaggaaatggccccatatcgtactccgttcccgaccccggagagccgccgaccggtgttagcctttccacgtgagttgccgatagctggcgaaccggctgacgtttacgaggctcttcagtcggcgcatgcggccttggcggcgagttcttaccccaaactgttatttaccggagaaccaggcgccctggtgtcgccggaatttgcggagcgttttgcagcgtcgttaactcgttgcgcattgattcgccttggcgcgggcctgcattacctgcaagaggatcatgctgatgcgataggccgctccgtggcgggctggattgccggcattgaagccgtccgcccgcagcttgccgcgtaa
BBa_M36291_sequence
1
tcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtc
BBa_M36363_sequence
1
aataattttgtttaactttaagaaggaggtatatccatggctagcatgactaaacatcttaatcatgctaaggaggttttctatactagatgtctaaaccgattgaaattgagattcggcgtgctccggtcttgggcagctcgatggcctatcgtgagactggtgcacaggatgctcccgttgtgctgttcctccacggcaatccgacctctagccatatttggcgcaacatcctgccactggttagtcccgttgctcactgcattgcgccggatctgattggtttcggccaatccggtaaaccggatattgcgtaccgctttttcgaccatgtccgttatttagacgcctttatcgaacagcgcggcgttacatcagcatatctggtggcgcaggactggggtaccgcgctggcgtttcatctggcagcgcgccgccccgactttgttcgtggactcgcctttatggaattcattcgcccgatgccgacgtggcaggacttccaccatacagaagtggccgaggaacaggatcacgcggaagctgcccgtgctgtgtttcgaaaattccgcacgccgggagagggagaagcaatgattcttgaagcaaacgccttcgtcgaaagggtgttaccgggcggcatcgtacgcaaactgggtgacgaggaaatggccccatatcgtactccgttcccgaccccggagagccgccgaccggtgttagcctttccacgtgagttgccgatagctggcgaaccggctgacgtttacgaggctcttcagtcggcgcatgcggccttggcggcgagttcttaccccaaactgttatttaccggagaaccaggcgccctggtgtcgccggaatttgcggagcgttttgcagcgtcgttaactcgttgcgcattgattcgccttggcgcgggcctgcattacctgcaagaggatcatgctgatgcgataggccgctccgtggcgggctggattgccggcattgaagccgtccgcccgcagcttgccgcgtaatactagagtcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtc
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z