BBa_M36011
1
BBa_M36011
Fur-regulated (Fe) Promoter
2011-04-25T11:00:00Z
2015-05-08T01:14:02Z
1. Gunter K, Toupet C, Schupp T. Characterization of an iron-regulated promoter involved in desferrioxamine B synthesis in Streptomyces pilosus: repressor-binding site and homology to the diphtheria toxin gene promoter. Journal of bacteriology. 1993;175(11):3295-302. Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=204726&tool=pmcentrez&rendertype=abstract.
pPS-PCR is a promoter which is controlled by the iron-repressive transcription factor, Fur.
false
false
_848_
0
9646
9
Not in stock
false
Based on deletion analysis of natural S. lividans gene
false
Brent Townshend
annotation2119770
1
SpeI
range2119770
1
159
164
annotation2119767
1
-35
range2119767
1
82
87
annotation2119769
1
start
range2119769
1
112
112
annotation2119768
1
-10
range2119768
1
103
108
annotation2119771
1
Possible repressor region
range2119771
1
102
120
annotation2119772
1
SalI
range2119772
1
95
100
BBa_M36729
1
BBa_M36729
EfeU elemental iron (II) transporter + 5' UTR (medium) + terminator
2011-05-01T11:00:00Z
2015-05-08T01:14:06Z
Basic parts.
This composite part has the EfeU iron transporter downstream from a medium 5' Bicistronic UTR. There is a terminator at the end.
false
false
_848_
0
9545
9
Not in stock
false
We are hoping that this 5' UTR will cause enough expression of the EfeU protein to measure, without producing so much that the organism dies due to excessive iron uptake or other ion imbalances.
false
Tom McLaughlin
component2118528
1
BBa_M36001
component2118529
1
BBa_M36042
component2118530
1
BBa_M36010
annotation2118529
1
BBa_M36042
range2118529
1
48
878
annotation2118528
1
BBa_M36001
range2118528
1
1
47
annotation2118530
1
BBa_M36010
range2118530
1
879
960
BBa_M36001
1
BBa_M36001
5' Bicistronic UTR (medium), does not include ATG start
2011-04-25T11:00:00Z
2015-05-08T01:14:02Z
Vivek Mutalik et al. c/o BIOFAB Emeryville.
5' UTR based on bicistronic junction architecture. First RBS is strong and drives expression of short leader cistron. Second RBS internal to first cistron control translation of gene of interest. Architecture is optimized so that downstream CDS for gene of interest does not have a chance to form a secondary structure with the 5' UTR. See BIOFAB.org for more information.
false
false
_848_
0
52
432
Not in stock
false
Please see long description.
false
Drew Endy
BBa_M36731
1
BBa_M36731
EfeU elemental iron (II) transporter + 5' UTR (medium) + terminator + Fur promoter
2011-05-02T11:00:00Z
2015-05-08T01:14:06Z
Basic parts.
This composite part has our actuator and sensor combined into a single sequence.
false
false
_848_
0
9545
9
Not in stock
false
After the terminator of the actual part, we have the Fur promoter. We're planning to place a universal sensor before this part (to trigger expression of EfeU) and a universal actuator after (to trigger expression of a signal when iron is low).
false
Tom McLaughlin
component2118613
1
BBa_M36011
component2118612
1
BBa_M36729
annotation2118612
1
BBa_M36729
range2118612
1
1
960
annotation2118613
1
BBa_M36011
range2118613
1
961
1124
BBa_M36042
1
BBa_M36042
EfeU elemental iron (II) transporter
2011-04-30T11:00:00Z
2015-05-08T01:14:02Z
From wild-type Nissle 1917 E. coli. The sequence came from the Ecogene entry EG13860.
This is the reconstructed gene for the EfeU iron transporter. This gene is inactive in K-12 strain E. coli, but has been characterized in the Nissle 1917 strain. (Grobe, Scherer et al. PMID: 16987175.)
false
false
_848_
0
9545
9
Not in stock
false
The sequence was conceptually reconstructed from the frame-shifted version. The Ecogene entry has an "N" for the nucleotide which is uncertain, but a comment in that entry says that the correct amino acid is likely glycine. Thus we chose N = G in the final sequence.
false
Tom McLaughlin
annotation2119094
1
Start codon
range2119094
1
1
3
annotation2119177
1
REGLE motif
range2119177
1
28
42
annotation2119195
1
REGLE motif
range2119195
1
385
399
annotation2119197
1
Stop codon
range2119197
1
829
831
annotation2119198
1
Repaired frameshift (see notes)
range2119198
1
106
106
BBa_M36010
1
BBa_M36010
Transcription Terminator (Strong)
2011-04-25T11:00:00Z
2015-05-08T01:14:02Z
Guillaume Cambray et al. c/o BIOFAB Emeryville
E. coli RNA pol transcription terminator designed and tested by Guillaume Cambray at BIOFAB Emeryville. Based on the natural E. coli rnpB T1 terminator.
false
true
_848_
0
52
432
Not in stock
false
please see long description
false
Drew Endy
BBa_M36001_sequence
1
tatagagggtattaataatgtatggattaaagggggaggcataacaa
BBa_M36011_sequence
1
gactgcaaagccggcgctccggtgaacgcttcacggccaatcgctgtgcatccggccacagttgacgggaatcaccccctgtggacttcctcaggtcgacattaggttaggctcacctaagttcatcgccccctgtggtgctcacccccaggagcatcactagt
BBa_M36729_sequence
1
tatagagggtattaataatgtatggattaaagggggaggcataacaaatgtttgttccgtttctcattatgttgcgcgaaggacttgaagccgcgctgattgtcagtttgattgccagctatcttaagcgtacccagcgaggccgatggattggtgtgatgtggattggcgtgttgcttgccgctgcgttgtgcctgggcttgggtatcttcattaacgaaaccaccggcgaatttccgcaaaaagaacaggaactgtttgaaggtatcgtggcggtgatcgccgtggtgatccttacctggatggttttctggatgcgcaaagtgtcgcgcaacgtcaaagtgcaactggaacaggcagtcgatagcgcattgcagcgtggaaatcatcatggctgggcgctggtgatgatggtcttttttgccgttgcaagggaagggctggagtcggtctttttcctgctggcggcatttcaacaagatgtcgggatctggccgccgctgggtgcaatgctcggtcttgctactgccgtggtgctaggcttcctgctctactggggcggtattcgcctcaatcttggtgcattttttaaatggaccagcctgtttattctcttcgtcgccgcagggctggcagctggtgccattcgcgcatttcatgaagccggattgtggaaccactttcaggaaatcgccttcgatatgagtgcggtgctctcaactcactcgctgtttggcacgctgatggaagggatttttggctatcaggaagcgccgagcgtcagcgaagtcgccgtctggtttatttatctcatcccggcgctggtggcatttgctctgccaccacgcgcaggggcgacagcgtctcgctccgcgtaatcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtc
BBa_M36010_sequence
1
tcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtc
BBa_M36731_sequence
1
tatagagggtattaataatgtatggattaaagggggaggcataacaaatgtttgttccgtttctcattatgttgcgcgaaggacttgaagccgcgctgattgtcagtttgattgccagctatcttaagcgtacccagcgaggccgatggattggtgtgatgtggattggcgtgttgcttgccgctgcgttgtgcctgggcttgggtatcttcattaacgaaaccaccggcgaatttccgcaaaaagaacaggaactgtttgaaggtatcgtggcggtgatcgccgtggtgatccttacctggatggttttctggatgcgcaaagtgtcgcgcaacgtcaaagtgcaactggaacaggcagtcgatagcgcattgcagcgtggaaatcatcatggctgggcgctggtgatgatggtcttttttgccgttgcaagggaagggctggagtcggtctttttcctgctggcggcatttcaacaagatgtcgggatctggccgccgctgggtgcaatgctcggtcttgctactgccgtggtgctaggcttcctgctctactggggcggtattcgcctcaatcttggtgcattttttaaatggaccagcctgtttattctcttcgtcgccgcagggctggcagctggtgccattcgcgcatttcatgaagccggattgtggaaccactttcaggaaatcgccttcgatatgagtgcggtgctctcaactcactcgctgtttggcacgctgatggaagggatttttggctatcaggaagcgccgagcgtcagcgaagtcgccgtctggtttatttatctcatcccggcgctggtggcatttgctctgccaccacgcgcaggggcgacagcgtctcgctccgcgtaatcggtcagtttcacctgatttacgtaaaaacccgcttcggcgggtttttgcttttggaggggcagaaagatgaatgactgtcgactgcaaagccggcgctccggtgaacgcttcacggccaatcgctgtgcatccggccacagttgacgggaatcaccccctgtggacttcctcaggtcgacattaggttaggctcacctaagttcatcgccccctgtggtgctcacccccaggagcatcactagt
BBa_M36042_sequence
1
atgtttgttccgtttctcattatgttgcgcgaaggacttgaagccgcgctgattgtcagtttgattgccagctatcttaagcgtacccagcgaggccgatggattggtgtgatgtggattggcgtgttgcttgccgctgcgttgtgcctgggcttgggtatcttcattaacgaaaccaccggcgaatttccgcaaaaagaacaggaactgtttgaaggtatcgtggcggtgatcgccgtggtgatccttacctggatggttttctggatgcgcaaagtgtcgcgcaacgtcaaagtgcaactggaacaggcagtcgatagcgcattgcagcgtggaaatcatcatggctgggcgctggtgatgatggtcttttttgccgttgcaagggaagggctggagtcggtctttttcctgctggcggcatttcaacaagatgtcgggatctggccgccgctgggtgcaatgctcggtcttgctactgccgtggtgctaggcttcctgctctactggggcggtattcgcctcaatcttggtgcattttttaaatggaccagcctgtttattctcttcgtcgccgcagggctggcagctggtgccattcgcgcatttcatgaagccggattgtggaaccactttcaggaaatcgccttcgatatgagtgcggtgctctcaactcactcgctgtttggcacgctgatggaagggatttttggctatcaggaagcgccgagcgtcagcgaagtcgccgtctggtttatttatctcatcccggcgctggtggcatttgctctgccaccacgcgcaggggcgacagcgtctcgctccgcgtaa
igem2sbol
1
iGEM to SBOL conversion
Conversion of the iGEM parts registry to SBOL2.1
Chris J. Myers
James Alastair McLaughlin
2017-03-06T15:00:00.000Z